Methods and nucleic acid molecules for aav vector selection
US-2024417717-A1 · Dec 19, 2024 · US
US8940290B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8940290-B2 |
| Application number | US-200913126557-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 29, 2009 |
| Priority date | Oct 31, 2008 |
| Publication date | Jan 27, 2015 |
| Grant date | Jan 27, 2015 |
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A recombinant vector comprises simian adenovirus 43, 45, 46, 47, 48, 49 or 50 sequences and a heterologous gene under the control of regulatory sequences. A cell line which expresses simian adenovirus 43, 45, 46, 47, 48, 49 or 50 gene(s) is also disclosed. Methods of using the vectors and cell lines are provided.
Opening claim text (preview).
The invention claimed is: 1. An adenovirus having a capsid comprising a hexon protein, a penton protein, and fiber protein, said hexon protein being a hexon protein of SAdV-46 comprising amino acids 1 to 959 of SEQ ID NO: 79; said capsid encapsidating a heterologous molecule comprising a gene operably linked to expression control sequences which direct transcription, translation, and/or expression thereof in a host cell. 2. The adenovirus according to claim…
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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