Tetrazines/trans-cyclooctenes in solid phase synthesis of labeled peptides
US-2015359913-A1 · Dec 17, 2015 · US
Radioiodination method
US8940274B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8940274-B2 |
| Application number | US-201113988880-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 23, 2011 |
| Priority date | Nov 23, 2010 |
| Publication date | Jan 27, 2015 |
| Grant date | Jan 27, 2015 |
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Abstract
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The present invention provides a novel method of labelling biological targeting molecules (BTMs) of interest with radioiodine. Also provided are functionalised BTMs useful in the method, as well as methods of preparing such functionalised BTMs under mild conditions.
First claim
Opening claim text (preview).
The invention claimed is: 1. A method of radioiodination of a biological targeting moiety, said method comprising: (i) provision of a functionalised BTM of Formula (Ia) or (Ib): (ii) reaction of the functionalised BTM of either Formula (Ia) or (Ib) with radioactive iodide ion in the presence of an oxidising agent, to give the desired radioiodinated product as a conjugate of…
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- A61K51/0453Primary
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
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Frequently asked questions
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- What does patent US8940274B2 cover?
- The present invention provides a novel method of labelling biological targeting molecules (BTMs) of interest with radioiodine. Also provided are functionalised BTMs useful in the method, as well as methods of preparing such functionalised BTMs under mild conditions.
- Who is the assignee on this patent?
- Avory Michelle, Wadsworth Harry John, Nairne Robert James Domett, and 1 more
- What technology area does this patent fall under?
- Primary CPC classification A61K51/0453. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Jan 27 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).