Pesticidal compositions and processes related thereto
US-9215870-B2 · Dec 22, 2015 · US
US8937181B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8937181-B2 |
| Application number | US-29678807-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 13, 2007 |
| Priority date | Apr 13, 2006 |
| Publication date | Jan 20, 2015 |
| Grant date | Jan 20, 2015 |
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The invention relates to azetidinyl, pyrrolidinyl, piperidinyl, and hexahydroazepinyl compounds of Formula (I): and pharmaceutically acceptable salts, prodrugs, or solvates thereof, wherein R 1 -R 3 , Z, p and q are defined as set forth in the specification. The invention is also directed to the use compounds of Formula (I) to treat, prevent or ameliorate a disorder responsive to the blockade of calcium channels, and particularly N-type calcium channels. Compounds of the present invention are especially useful for treating pain.
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What is claimed is: 1. A compound having the Formula I: or a pharmaceutically acceptable salt thereof, wherein: R 1 and R 2 are each independently selected from the group consisting of hydrogen, alkyl, haloalkyl, halogen, alkoxy, haloalkoxy, cyano, nitro, amino, aminoalkyl, alkylamino, dialkylamino, and hydroxy; R 3 is selected from the group consisting of alkyl, alkenyl,…
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