High Backscattering Waveguides
US-2016356709-A1 · Dec 8, 2016 · US
US8934103B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8934103-B2 |
| Application number | US-201213663069-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 29, 2012 |
| Priority date | Dec 22, 2011 |
| Publication date | Jan 13, 2015 |
| Grant date | Jan 13, 2015 |
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Systems and methods described herein employ multiple phase-contrast images with various relative phase shifts between light diffracted by a sample and light not diffracted by the sample to produce a quantitative phase image. The produced quantitative phase image may have sufficient contrast for label-free auto-segmentation of cell bodies and nuclei.
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The invention claimed is: 1. A system for phase contrast imaging of a sample comprising: a light source for illuminating the sample, wherein a first beam splitter generates from the light source at least a first beam of light and a second beam of light, wherein a first optical element is configured to collect light from the first beam of light that is not diffracted by the sample, and wherein a second optical element is configured to collect light from the second beam of light tha…
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