Volumetric Imaging
US-2024418652-A1 · Dec 19, 2024 · US
US8933418B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8933418-B2 |
| Application number | US-201213541174-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 3, 2012 |
| Priority date | Jul 11, 2011 |
| Publication date | Jan 13, 2015 |
| Grant date | Jan 13, 2015 |
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A sample observation apparatus includes excitation light irradiation unit to irradiate sample with excitation light; excitation light modulator to modulate spatial intensity distribution of the excitation light on the sample; excitation light modulation control unit to control the excitation light modulator according to modulation control signal; photo detection unit to detect light emission from the sample and to generate a detection signal; image generation unit to generate image data of the sample according to the modulation control signal and the detection signal; modulation control signal generation unit to generate the modulation control signal such that Nyquist frequency of the image data will be larger than cut-off frequency in the spatial intensity distribution of the excitation light on the sample; and image processing unit to emphasize high-frequency component that exceeds the cut-off frequency included in the image data.
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What is claimed is: 1. A sample observation apparatus comprising: an excitation light irradiation unit to irradiate a sample with an excitation light; an excitation light modulation unit to modulate a spatial intensity distribution of the excitation light on the sample; an excitation light modulation control unit to control the excitation light modulation unit according to a modulation control signal; a photo detection unit to detect light emission from the sample caused by…
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