Inhibitors of tyk2
US-2024425484-A1 · Dec 26, 2024 · US
Pyridazine compounds, compositions and methods
US8933076B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8933076-B2 |
| Application number | US-201213491986-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 8, 2012 |
| Priority date | Nov 2, 2004 |
| Publication date | Jan 13, 2015 |
| Grant date | Jan 13, 2015 |
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Abstract
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The invention relates to novel chemical compounds, compositions and methods of making and using the same. In particular, the invention provides pyridazine compounds and/or related heterocyclic derivatives, compositions comprising the same, and methods of making and using pyridazine compounds and/or related heterocyclic derivatives and compositions comprising the same, for modulation of cellular pathways (e.g., signal transduction pathways), for treatment or prevention of inflammatory diseases (e.g., Alzheimer's disease), for, research, drug screening, and therapeutic applications.
First claim
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What is claimed is: 1. A method for reducing neuroinflammation to treat a disease or condition which presents neuroinflammation in a subject comprising administering to the subject a compound of the formula Ib: wherein: R 1 is a piperazinyl radical which is substituted with a pyrimidinyl or pyridinyl radical; R 2 and R 3 are independently hydrogen, hydroxyl, alkyl,…
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Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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- What does patent US8933076B2 cover?
- The invention relates to novel chemical compounds, compositions and methods of making and using the same. In particular, the invention provides pyridazine compounds and/or related heterocyclic derivatives, compositions comprising the same, and methods of making and using pyridazine compounds and/or related heterocyclic derivatives and compositions comprising the same, for modulation of cellular…
- Who is the assignee on this patent?
- Watterson D Martin, Van Eldik Linda, Haiech Jacques, and 8 more
- What technology area does this patent fall under?
- Primary CPC classification C07D401/12. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jan 13 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).