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Medical device coatings for releasing a therapeutic agent at multiple rates
US8932345B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8932345-B2 |
| Application number | US-2549508-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 4, 2008 |
| Priority date | Feb 7, 2007 |
| Publication date | Jan 13, 2015 |
| Grant date | Jan 13, 2015 |
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Abstract
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Medical device coatings are provided that simultaneously release a therapeutic agent at different rates from different portions of the medical device coating. In a first embodiment, medical device coatings are provided that include particles comprising a therapeutic agent with two or more different particles sizes within a single layer on a surface of the implantable device. In a second embodiment, medical device coatings are provided having a higher concentration of the therapeutic agent in a first region of the coating than in a second region of the coating. In a third embodiment, medical device coatings are provided that are formed by certain coating processes wherein the droplet size of a spray coating solution is changed during the coating process. These coating processes preferably include applying a solution comprising a therapeutic agent and a suitable solvent to a surface of an implantable medical device. In a fourth embodiment, methods of treatment are provided that include implanting a coated medical device.
First claim
Opening claim text (preview).
We claim: 1. An implantable medical device having a coating on an abluminal surface extending from a proximal end to a distal end, the coating formed by the steps of: spraying droplets having a first average liquid droplet size and comprising a solution of a volatile solvent and a taxane therapeutic agent onto a first region of the abluminal surface; evaporating the volatile solvent to form a coating of the taxane therapeutic agent on the first region; spraying droplets having…
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Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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Frequently asked questions
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- What does patent US8932345B2 cover?
- Medical device coatings are provided that simultaneously release a therapeutic agent at different rates from different portions of the medical device coating. In a first embodiment, medical device coatings are provided that include particles comprising a therapeutic agent with two or more different particles sizes within a single layer on a surface of the implantable device. In a second embodim…
- Who is the assignee on this patent?
- Moore William F, Shirley Gary Bradford, Cook Medical Technologies Llc
- What technology area does this patent fall under?
- Primary CPC classification A61L27/34. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Jan 13 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).