Systems and methods for assessing images

Patent metadata

Field	Value
Publication number	US-8929630-B2
Application number	US-74815810-A
Country	US
Kind code	B2
Filing date	Mar 26, 2010
Priority date	Mar 27, 2009
Publication date	Jan 6, 2015
Grant date	Jan 6, 2015

Abstract

Disclosed are systems and methods for assessing images in applications such as microscopic scanning of a slide having light emitting objects. In certain embodiments, such scanning can involve objects such as sequencing beads disposed on the slide to facilitate biological analysis such as nucleic acid sequencing. Also disclosed are certain embodiments where images of light emitting objects are assessed for image quality so as to facilitate a feedback response such as a corrective action. In certain embodiments, such assessment and correction can be performed in real-time during the scanning process, and can include re-acquisition of the assessed image. Also disclosed are certain embodiments where such assessment and correction can be triggered dynamically during the scan, or before start of the scan, so as to enhance the scanning performance, including scanning time and throughput.

First claim

What is claimed is:

1. A nucleic acid sequencing system, comprising:
a reaction chamber including a surface with one or more nucleic acid molecules disposed on said surface,
wherein said surface is populated with a plurality of labeled oligonucleotide probes arranged in a plurality of panels, and
wherein said plurality of oligonucleotide probes generate detectable signals and query the sequence of at least a portion of said one or more nucleic acid molecules;
an imaging syst…

Assignees

• Fu Haoning
• Life Technologies Corp

Inventors

• Fu Haoning

Classifications

• G01N21/6428 Primary

  Physics · mapped topic

• G06T7/0012

  Physics · mapped topic

• G01N2021/6441

  Physics · mapped topic

• G01N21/6456 Primary

  Physics · mapped topic

• G06T2207/30072

  Physics · mapped topic