Method of preparing oligomeric compounds using modified coupling protocols
US-2015368288-A1 · Dec 24, 2015 · US
US8927520B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8927520-B2 |
| Application number | US-201113976826-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 22, 2011 |
| Priority date | Dec 27, 2010 |
| Publication date | Jan 6, 2015 |
| Grant date | Jan 6, 2015 |
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The present invention relates to compounds of formula (I): wherein Rj, R2, R3, R4, Xi, X2, X3 and Z are as defined in claim 1. The compounds are useful in the prevention and/or treatment of bacterial infections.
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The invention claimed is: 1. A compound of formula (A): or a tautomer, stereoisomer, mixture of stereoisomers, or pharmaceutically acceptable salt thereof, wherein R 1 is H, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, or C 2 -C 6 alkynyl; an alkyl, alkenyl, or alkynyl group in R 1 if present is optionally substituted by SR 5 , NR 5 R 5A , or OR 5 ; R 2…
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