Eye mounted device for therapeutic agent release
US-12167978-B2 · Dec 17, 2024 · US
US8927005B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8927005-B2 |
| Application number | US-201313741103-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 14, 2013 |
| Priority date | Feb 9, 2005 |
| Publication date | Jan 6, 2015 |
| Grant date | Jan 6, 2015 |
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Described herein are liquid formulations which deliver a variety of therapeutic agents, including but not limited to rapamycin, to a subject for an extended period of time; liquid formulations which form a non-dispersed mass when placed in an aqueous medium of a subject; liquid formulations, comprising a therapeutic agent and a plurality of polymers; and methods for delivering therapeutic agents to a subject for an extended period of time using the liquid formulations. The liquid formulation may be placed in an aqueous medium of a subject, including but not limited to via intraocular or periocular administration. A method may be used to administer rapamycin to treat or prevent angiogenesis, choroidal neovascularization, or age-related macular degeneration in a subject.
Opening claim text (preview).
The invention claimed is: 1. A method for treating uveitis in a human subject, the method comprising administering to the human subject by periocular injection a volume of a liquid formulation comprising an effective amount of a therapeutic agent to treat uveitis in the human subject for at least one month, wherein the liquid formulation comprises between 0.5% (w/w) to 6.0% (w/w) of the therapeutic agent, between 80% (w/w) to 99% (w/w) of polyethylene glycol, and ethanol, the…
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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