Explant Plug Devices for Use in VAD Explantation

Patent metadata

Field	Value
Publication number	US-2026069856-A1
Application number	US-202519389771-A
Country	US
Kind code	A1
Filing date	Nov 14, 2025
Priority date	May 17, 2023
Publication date	Mar 12, 2026
Grant date	—

Abstract

Explant plug devices for attachment to a ventricular cuff during explantation of a ventricular assist device. An explant plug device includes a blood flow blocking component and a retention clip. The blood flow blocking component is configured to be mounted to the ventricular cuff to block flow of blood out of the ventricle via the ventricular cuff. The retention clip is coupled with the blood flow blocking component. The retention clip is repositionable relative to the blood flow blocking component from a retracted position that accommodates mounting of the blood flow blocking component to the ventricular cuff and a retention position that retains the blood flow blocking component to the ventricular cuff.

First claim

1 . An explant plug device mountable to a ventricular cuff in fluid communication with a ventricle to block blood from flowing out of the ventricle through a blood flow channel of the ventricular cuff, the explant plug device comprising:
a seal assembly configured for insertion into the blood flow channel and blocking blood flow through the blood flow channel; and a retention assembly comprising one or more retention members and a spring assembly coupled with the one or more retention members, wherein the retention assembly is reconfigurable between an insertion configuration and a retention configuration, wherein each of the one or more retention members in the insertion configuration is positioned to accommodate insertion of the retention assembly into the blood flow channel of the ventricular cuff, and wherein the spring assembly in the retention configuration is configured to hold each of the one or more retention members in engagement with an inner surface of the ventricular cuff that defines the blood flow channel.

2 . The explant plug device of claim 1 , wherein:
the spring assembly comprises one or more preloaded springs; and the preloaded springs are configured to hold each of the one or more retention members in engagement with the inner surface of the ventricular cuff in the retention configuration.

3 . The explant plug device of claim 2 , wherein:
the one or more retention members comprise a first retention member and a second retention member; the first retention member is configured for engaging a first annular portion of the inner surface in the retention configuration; the second retention member is configured for engaging a second annular portion of the inner surface in the retention configuration; and the second annular portion of the inner surface is disposed opposite to the first annular portion of the inner surface.

4 . The explant plug device of claim 1 , wherein:
the retention assembly comprises a frame member to which the seal assembly is attached; and each of the one or more retention members is coupled with the frame member to accommodate movement of the retention member relative to the frame member.

5 - 7 . (canceled)

8 . The explant plug device of claim 1 , wherein the seal assembly is configured to extend into the ventricle.

9 . The explant plug device of claim 1 , wherein:
the seal assembly comprises a base assembly, a ventricle opening member, and an adjustment assembly; the base assembly is mounted to the retention assembly and configured for blocking blood flow through the blood flow channel; the ventricle opening member is configured for filling an opening in a ventricular wall to which the ventricular cuff is attached; the ventricle opening member is coupled to the base assembly via the adjustment assembly; and the adjustment assembly is operable to adjust a distance between the ventricle opening member and the base assembly.

10 - 40 . (canceled)

41 . An explant plug device mountable to a ventricular cuff in fluid communication with a ventricle to block blood from flowing out of the ventricle through the ventricular cuff, wherein the ventricular cuff comprises an outwardly facing annular flange, an outwardly facing annular groove, and a blood flow channel for an inlet cannula of a blood pump, the explant plug device comprising:
a blood flow blocking component configured to be mounted to the ventricular cuff to block flow of blood out of the ventricle via the ventricular cuff; and a retention clip coupled with the blood flow blocking component, wherein the retention clip is repositionable relative to the blood flow blocking component from a retracted position that accommodates mounting of the blood flow blocking component to the ventricular cuff and a retention position that engages the outwardly facing annular flange to retain the blood flow blocking component to the ventricular cuff.

42 . The explant plug device of claim 41 , wherein the retention clip comprises retention clip arms that extend within retention clip arm passages of the blood flow blocking component and into the outwardly facing annular groove when the retention clip is in the retention position.

43 . The explant plug device of claim 42 , wherein, when the blood flow blocking component is not mounted onto the ventricular cuff, the retention clip is blocked from being repositioned to the retention position from the retracted position.

44 . The explant plug device of claim 43 , further comprising a lockout component pivotally coupled with the retention clip, wherein:
the lockout component is held in a blocking orientation relative to the retention clip in which the lockout component blocks the retention clip from being repositioned to the retention position from the retracted position when the blood flow blocking component is not mounted onto the ventricular cuff; and mounting of the blood flow blocking component to the ventricular cuff reorients the lockout component relative to the retention clip from the blocking orientation to a non-blocking orientation that accommodates repositioning of the retention clip to the retention position from the retracted position.

45 . The explant plug device of claim 44 , wherein the retention clip comprises a spring arm that engages the lockout component to hold the lockout component in the blocking orientation when the blood flow blocking component is not mounted onto the ventricular cuff.

46 . The explant plug device of claim 44 , further comprising a recess, wherein:
the recess is configured to accommodate a protruding portion of the lockout component; and the recess is configured to engage the protruding portion of the lockout component to block the retention clip from being repositioned to the retention position from the retracted position when the lockout component is in the blocking orientation.

47 . The explant plug device of claim 43 , further comprising a stop component, wherein:
the stop component is biased to a blocking position when the blood flow blocking component is not mounted to the ventricular cuff; the stop component in the blocking position is configured to engage the retention clip to block repositioning of the retention clip to the retention position from the retracted position; and mounting of the blood flow blocking component to the ventricular cuff repositions the stop component from the blocking position to a non-blocking position that accommodates repositioning of the retention clip to the retention position from the retracted position.

48 . The explant plug device of claim 47 , further comprising a stop component spring that biases the stop component to the blocking position when the blood flow blocking component is not mounted to the ventricular cuff, and wherein the stop component is configured to be engaged by the ventricular cuff during mounting of the blood flow blocking component to the ventricular cuff to displace the stop component from the blocking position to the non-blocking position.

49 . The explant plug device of claim 43 , further comprising a two-part cam mechanism mounted to the retention clip, wherein:
the two-part cam mechanism is biased to a blocking configuration when the blood flow blocking component is not mounted to the ventricular cuff; the two-part cam mechanism in the blocking configuration is configured to block repositioning of the retention clip to the retention position from the retracted position; and mounting of the blood flow blocking component to the ventricular cuff reconfigures the two-part cam mechanism from the blocking configura

Assignees

• Tc1 Llc

Inventors

• Harjes Daniel I
• Keen Rachel
• Ramos Rebecca
• Franklin Stephen
• Cashton Samantha
• Afanasewicz Elizabeth
• Nagle Grey
• Grace Christopher

Classifications

• A61M60/178 Primary

  drawing blood from a ventricle and returning the blood to the arterial system via a cannula external to the ventricle, e.g. left or right ventricular assist devices · CPC title

• A61B17/0057

  Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect (sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009) · CPC title

• A61M60/90

  Details not provided for in groups A61M60/40, A61M60/50 or A61M60/80 · CPC title

• A61M60/861

  Connections or anchorings for connecting or anchoring pumps or pumping devices to parts of the patient's body · CPC title

• A61M60/863 Primary

  Apex rings · CPC title