Use of fatty acids for microbiome benefit and compositions comprising the same

Patent metadata

Field	Value
Publication number	US-2026060908-A1
Application number	US-202319101606-A
Country	US
Kind code	A1
Filing date	Jul 3, 2023
Priority date	Aug 8, 2022
Publication date	Mar 5, 2026
Grant date	—

Abstract

The present invention relates to use of specific group of fatty acids and compositions comprising them for delivering microbiome benefit to skin. This benefit ensures that the skin is protected against undesirable bacteria. The present invention delivers the benefit by the selective fatty acids i.e one having C18 carbons atoms or more. preferably one having C20 carbon atoms or more acting as prebiotics for skin commensal bacteria like S. epidermidis and S Hominis . The efficacy is improved by combining fatty acids with poly hydric alcohol like glycerol and/or by combining with fatty acid esters like glycerol monostearate. Combination of certain unsaturated fatty acids is also seen to interact synergistically to provide this benefit.

First claim

1 .- 8 . (canceled)

9 . A composition comprising:
(i) 0.2 to 10 wt % C20 to C24 fatty acid, (ii) 0.25 to 80 wt % of a surfactant; and (iii) a cosmetically acceptable carrier,
wherein the composition comprises less than 1 wt %, of a C10 to C18 fatty acid.

10 . A composition comprising:
(i) 0.2 to 10 wt % C16 to C18 fatty acid, (ii) a polyhydric alcohol; (iii) 0.25 to 80 wt % of a surfactant; and (iv) a cosmetically acceptable carrier;
wherein the composition comprises less than 1 wt %, of a C10 to C14 fatty acid.

11 . The composition as claimed in claim 10 , wherein the C16 to C18 fatty acid comprises a mixture of oleic acid and linoleic acid.

12 . The composition as claimed in claim 9 , wherein the composition is a leave-on product in the form of a cream, lotion, or gel.

13 . The composition as claimed in claim 9 , wherein the surfactant is selected from one or more of a synthetic anionic or amphoteric surfactant.

14 . The composition as claimed in claim 9 further comprising a fatty acid ester.

15 . The composition as claimed in claim 9 , wherein the composition comprises less than 0.1 wt % of the C10 to C18 fatty acid.

16 . The composition as claimed in claim 9 , wherein the composition is a wash-off product.

17 . The composition as claimed in claim 16 , wherein the surfactant comprises alkyl taurate.

18 . The composition as claimed in claim 10 , wherein the polyhydric alcohol is glycerol.

19 . The composition as claimed in claim 10 , wherein the composition comprises less than 0.1 wt % of the C10 to C14 fatty acid.

20 . The composition as claimed in claim 10 , wherein the composition is a leave-on product in the form of a cream, lotion, or gel.

21 . The composition as claimed in claim 10 , wherein the composition is a wash-off product.

22 . The composition as claimed in claim 21 , wherein the surfactant comprises alkyl taurate.

23 . The composition as claimed in claim 10 , wherein the surfactant is selected from one or more of a synthetic anionic or amphoteric surfactant.

24 . The composition as claimed in claim 14 , wherein the fatty acid ester is glycerol monostearate.

25 . The composition as claimed in claim 10 further comprising a fatty acid ester.

26 . The composition as claimed in claim 25 , wherein the fatty acid ester is glycerol monostearate.

Assignees

• Conopco Inc Dba Unilever

Inventors

• Dasgupta Anindya
• Kumaran Srikala

Classifications

• A61Q19/10

  Washing or bathing preparations · CPC title

• A61Q17/00

  Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings · CPC title

• A61K2800/596

  Mixtures of surface active compounds · CPC title

• A61K2800/5922

  At least two compounds being classified in the same subclass of A61K8/18 · CPC title

• A61K8/345

  containing more than one hydroxy group · CPC title