Fluid injector system with improved ratio performance

Patent metadata

Field	Value
Publication number	US-2026027295-A1
Application number	US-202519343381-A
Country	US
Kind code	A1
Filing date	Sep 29, 2025
Priority date	Feb 23, 2021
Publication date	Jan 29, 2026
Grant date	—

Abstract

A fluid injector system includes a control device operatively associated with a first drive component configured to pressurize and inject a first fluid and a second drive component configured to pressurize and inject a second fluid. The control device includes at least one processor programmed or configured to: during a first phase of a multi-phase injection protocol, actuate at least the first drive component to inject the first phase; during the first phase of the injection protocol and prior to transitioning to a second phase of the injection protocol, actuate the second drive component to pressurize the second fluid relative to a pressure of the first fluid; and during the second phase of the injection protocol, actuate the second drive component to inject at least the second fluid so that a desired steady-state ratio of the first fluid and the second fluid in the second phase is reached.

First claim

We claim:

1 . A computer program product for performing an injection protocol using a fluid injector system, the injection protocol including at least a first phase and a second phase subsequent to the first phase, the computer program product comprising:
non-transitory computer readable media comprising one or more instructions that, when executed by at least one processor of the fluid injector system, cause the at least one processor to:
during the first phase of the injection protocol, actuate at least a first drive component of the fluid injector system to inject the first phase including a first fluid through a fluid conduit;
during the first phase of the injection protocol prior to transitioning to the second phase of the injection protocol, actuate a second drive component of the fluid injector system to pressurize a second fluid relative to a pressure of a first fluid in the fluid conduit; and
during the second phase of the injection protocol, actuate the second drive component to inject at least the second fluid through the fluid conduit so that a desired steady-state ratio of the first fluid and the second fluid in the second phase is reached.

2 . The computer program product of claim 1 , wherein the first fluid comprises a contrast medium and the second fluid comprises a diluent.

3 . The computer program product of claim 1 , wherein the desired steady-state ratio of the first fluid and the second fluid in the second phase is reached at a quicker rate than if the second drive component is not actuated prior to transitioning to the second phase of the injection protocol.

4 . The computer program product of claim 1 , wherein the one or more instructions, when executed by the at least one processor of the fluid injector system, further cause the at least one processor to: during the first phase of the injection protocol prior to transitioning to the second phase of the injection protocol, cease actuation or reduce a speed of the first drive component.

5 . The computer program product of claim 1 , wherein the one or more instructions, when executed by at least one processor of the fluid injector system, further cause the at least one processor to: during the second phase of the injection protocol, adjust a speed of the first drive component to inject the first fluid at a flow rate to reach the desired steady-state ratio of the first fluid and the second fluid through the fluid conduit during the second phase of the injection protocol.

6 . The computer program product of claim 1 , wherein the fluid injector system further comprises at least a first valve controlling fluid communication between the fluid conduit and a first reservoir containing the first fluid, and a second valve controlling fluid communication between the second reservoir and the fluid conduit, and
wherein the one or more instructions, when executed by at least one processor of the fluid injector system, further cause the at least one processor to close the second valve prior to pressurizing the second fluid relative to the pressure of the first fluid in the fluid conduit.

7 . The computer program product of claim 6 , wherein the one or more instructions, when executed by at least one processor of the fluid injector system, further cause the at least one processor to: open the second valve isolating the second fluid reservoir from the first fluid reservoir and the fluid conduit during a transition from the first phase of the injection protocol to the second phase of the injection protocol.

8 . The computer program product of claim 1 , wherein pressurizing the second fluid relative to the pressure of the first fluid comprises selecting a pressure ratio of the pressure of the first fluid and a pressure of the second fluid to reach the desired steady-state flow ratio of the first fluid and the second fluid for the second phase.

9 . The computer program product of claim 1 , wherein pressurizing the second fluid relative to the pressure of the first fluid comprises gradually increasing a pressure of the second fluid such that, at a transition from the first phase of the injection protocol to the second phase of the injection protocol, the pressure of the second fluid is substantially equal to the pressure of the first fluid.

10 . The computer program product of claim 1 , the one or more instructions, when executed by at least one processor of the fluid injector system, further cause the at least one processor to: during the first phase of the injection protocol prior to transitioning to the second phase of the injection protocol, adjusting at least one property of the injection protocol to prevent backflow of the first fluid into the second fluid reservoir.

11 . The computer program product of claim 10 , wherein adjusting at least one property of the injection protocol comprises at least one of: advancing the second drive component at a constant speed, linearly increasing a speed of the second drive component, and exponentially increasing the speed of the second drive component.

12 . A method of performing an injection protocol comprising at least a first phase and a second phase using a fluid injector system, the second phase subsequent to the first phase, the method comprising:
providing a control device operatively associated with a first drive component and a second drive component, the first drive component configured to pressurize and inject a first fluid from a first fluid reservoir through a fluid conduit, the second drive component configured to pressurize and inject a second fluid from a second fluid reservoir through the fluid conduit, actuating at least one of the first drive component and the second drive component to inject at least one of the first fluid and the second fluid through the fluid conduit at a first desired steady-state ratio during the first phase of the injection protocol; actuating the first drive component and the second drive component to inject the first fluid and the second fluid through the fluid conduit such that a volumetric ratio of the second fluid displaced from the second fluid reservoir relative to the first fluid displaced from the first fluid reservoir exceeds a second desired steady-state ratio during an initial portion of the second phase of the injection protocol; and actuating at least one of the first drive component and the second drive component to reduce the volumetric ratio until the volumetric ratio reaches the second desired steady-state ratio of the first fluid and the second fluid in the second phase subsequent to the initial portion of the second phase.

13 . The method of claim 12 , wherein the first fluid comprises a contrast medium and the second fluid comprises a diluent.

14 . The method of claim 12 , wherein the second desired steady-state ratio of the first fluid and the second fluid in the second phase is reached at a quicker rate than if the actuation of the first drive component and the second drive component to inject the first fluid and the second fluid through the fluid conduit such that a volumetric ratio of the second fluid displaced from the second fluid reservoir relative to the first fluid displaced from the first fluid reservoir does not exceed a second desired steady-state ratio.

15 . The method of claim 12 , further comprising ceasing actuation or reduce a speed of the first drive component during the first phase of the injection protocol prior to transitioning to the second phase of the injection protocol.

16 . The method of claim 12 , wherein the fluid injector system further comprises at least a first valve controlling fluid com

Assignees

• Bayer Healthcare Llc

Inventors

• Chaya Amy
• Spohn Michael
• Mcdermott Michael
• Barone William

Classifications

• A61M2205/52

  with memories providing a history of measured variating parameters of apparatus or patient · CPC title

• A61M2005/14208

  with a programmable infusion control system, characterised by the infusion program · CPC title

• A61M5/1422

  with double acting or multiple pistons · CPC title

• A61M5/1408 Primary

  in parallel, e.g. manifolds, sequencing valves (access sites A61M39/02; tube connectors A61M39/10) · CPC title

• A61M5/16827 Primary

  controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths (infusion of multiple fluids without using a controller A61M5/1407) · CPC title