Ion focusing

Patent metadata

Field	Value
Publication number	US-2025391650-A1
Application number	US-202519316356-A
Country	US
Kind code	A1
Filing date	Sep 2, 2025
Priority date	Jun 6, 2012
Publication date	Dec 25, 2025
Grant date	—

Abstract

The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing ions that includes an electrode having a cavity, at least one inlet within the electrode configured to operatively couple with an ionization source, such that discharge generated by the ionization source is injected into the cavity of the electrode, and an outlet. The cavity in the electrode is shaped such that upon application of voltage to the electrode, ions within the cavity are focused and directed to the outlet, which is positioned such that a proximal end of the outlet receives the focused ions and a distal end of the outlet is open to ambient pressure.

First claim

1 - 20 . (canceled)

21 . A method for collecting compounds comprising amino acids, the apparatus comprising,
providing an apparatus comprising: an electrode comprising a cavity, an inlet, and an outlet; injecting a discharge comprising compounds comprising amino acids from an emitter into the cavity via the inlet in the cavity, wherein the cavity in the electrode is shaped such that upon application of voltage to the electrode, the compounds comprising amino acids within the cavity are focused and directed to the outlet, which is positioned such that a proximal end of the outlet receives a focused beam and a distal end of the outlet is open to ambient pressure; and collecting in a concentrated form the compounds comprising amino acids.

22 . The method according to claim 21 , wherein the interior of the cavity comprises an ellipsoidal shape.

23 . The method according to claim 22 , wherein the cavity is pressurized.

24 . The method according to claim 22 , wherein the outlet is connected to the electrode.

25 . The method according to claim 22 , wherein the outlet is spaced from the electrode.

26 . The method according to claim 22 , wherein the outlet is grounded.

27 . The method according to claim 21 , further comprising a gas inlet.

28 . The method according to claim 21 , further comprising a plurality of ring electrodes positioned within an interior portion of the cavity such that they are aligned with the outlet, wherein the electrodes are arranged in order of decreasing inner diameter with respect to the outlet.

29 . The method according to claim 21 , wherein the collected compounds comprising amino acids generate crystalline material.

30 . The method according to claim 21 , wherein the collected compounds comprising amino acids are subsequently analyzed.

Assignees

• Purdue Research Foundation

Inventors

• Cooks Robert Graham
• Baird Zane
• Peng Wen-Ping

Classifications

• H01J49/26

  Mass spectrometers or separator tubes · CPC title

• H01J49/165

  Electrospray ionisation · CPC title

• H01J49/10

  Ion sources; Ion guns · CPC title

• H01J49/06

  Electron- or ion-optical arrangements · CPC title

• H01J49/067 Primary

  Ion lenses, apertures, skimmers · CPC title