Channel chip

Patent metadata

Field	Value
Publication number	US-2025381572-A1
Application number	US-202318881083-A
Country	US
Kind code	A1
Filing date	Jul 7, 2023
Priority date	Jul 21, 2022
Publication date	Dec 18, 2025
Grant date	—

Abstract

A channel chip includes a plurality of filter layers, a first common supply passage, a common channel, and a dielectrophoretic layer. The plurality of filter layers each have an HDF. The first common supply passage supplies a sample liquid to the HDFs of the plurality of filter layers. The liquid that has passed through the plurality of HDFs passes through the common channel. The dielectrophoretic layer includes electrodes for causing dielectrophoresis of dielectric particles contained in a liquid passing through the common channel. The plurality of filter layers and the dielectrophoretic layer are stacked.

First claim

1 . A channel chip comprising:
a plurality of filter layers each having a hydrodynamic filter; a common supply passage that supplies a sample liquid to the hydrodynamic filters of the plurality of filter layers; a common channel through which a liquid that has passed through the plurality of hydrodynamic filters passes; and a dielectrophoretic layer having electrodes that cause dielectrophoresis of dielectric particles contained in the liquid passing through the common channel, wherein the plurality of filter layers and the dielectrophoretic layer are stacked.

2 . The channel chip according to claim 1 , wherein the plurality of filter layers include a first filter layer stacked on the dielectrophoretic layer and one or more second filter layer stacked on the first filter layer, and
the common channel is disposed in the first filter layer.

3 . The channel chip according to claim 2 , wherein the plurality of filter layers include a plurality of the second filter layers,
the channel chip includes a plurality of outlet-side connection channels connecting outlets of the hydrodynamic filters of the plurality of second filter layers and the common channel, and the plurality of outlet-side connection channels extend to the first filter layer and are connected to the common channel without joining together in the plurality of second filter layers.

4 . The channel chip according to claim 1 , wherein each of the filter layers has the plurality of hydrodynamic filters.

5 . The channel chip according to claim 4 , wherein the plurality of hydrodynamic filters of each of the filter layers are disposed symmetrically with respect to the common channel.

6 . The channel chip according to claim 4 , wherein the channel chip includes a plurality of inlet-side connection channels that connect the common supply passage and inlets of the plurality of hydrodynamic filters in each of the filter layers, and
in each of the filter layers, the plurality of inlet-side connection channels has substantially the same channel length.

7 . The channel chip according to claim 4 , further comprising a first recovery passage and a pair of second recovery passages connected to a downstream portion of the common channel,
wherein the pair of second recovery passages are disposed such as to sandwich the first recovery passage, and the dielectric particles separated from the liquid that has passed through the hydrodynamic filter flow through the first recovery passage.

Assignees

• Screen Holdings Co Ltd

Inventors

• Urakawa Satoshi
• Sanada Masakazu

Classifications

• B03C2201/26

  for use in medical or biological applications · CPC title

• B01L2400/0424

  Dielectrophoretic forces · CPC title

• B01L2300/0864

  comprising only one inlet and multiple receiving wells, e.g. for separation, splitting · CPC title

• B01L2300/0681

  Filter · CPC title

• B01L3/502753

  characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation · CPC title