Blood purification column
US-2015374898-A1 · Dec 31, 2015 · US
US2025367357A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2025367357-A1 |
| Application number | US-202418951022-A |
| Country | US |
| Kind code | A1 |
| Filing date | Nov 18, 2024 |
| Priority date | May 30, 2024 |
| Publication date | Dec 4, 2025 |
| Grant date | — |
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A resin is formed through a ring-opening reaction of dextran sulfate sodium salt and a modified polyether sulfone. The modified polyether sulfone is formed by a reaction of polyether sulfone and an epoxy compound containing a carbon-carbon double bond. The resin may serve as an adsorption material, which can be a porous film or a porous hollow fiber. The adsorption material can be in contact with blood to lower LDL-C concentration in the blood.
Opening claim text (preview).
What is claimed is: 1 . A resin, formed through a ring-opening reaction of dextran sulfate sodium salt and a modified polyether sulfone, wherein the modified polyether sulfone is formed by a reaction of polyether sulfone and an epoxy compound containing a carbon-carbon double bond. 2 . The resin as claimed in claim 1 , wherein the polyether sulfone and the epoxy compound containing a carbon-carbon double bond have a weight ratio of 100:20 to 100:30. 3 . The resin as claimed in claim 1 , wherein the modified polyether sulfone and the dextran sulfate sodium salt have a weight ratio of 100:1 to 100:1500. 4 . The resin as claimed in claim 1 , wherein a repeating unit of the polyether sulfone is or a combination thereof. 5 . The resin as claimed in claim 1 , wherein the polyether sulfone has a weight average molecular weight of 55,000 g/mol to 75,000 g/mol. 6 . The resin as claimed in claim 1 , wherein the dextran sulfate sodium salt has a weight average molecular weight of 5000 g/mol to 10000 g/mol. 7 . The resin as claimed in claim 1 , wherein the epoxy compound containing a carbon-carbon double bond is or a combination thereof. 8 . An adsorption material, comprising the resin as claimed in claim 1 , wherein the adsorption material is in a form of a porous film or a porous hollow fiber. 9 . The adsorption material as claimed in claim 8 , wherein the adsorption material has a porosity of 60% to 90%. 10 . The adsorption material as claimed in claim 8 , wherein the porous film has a thickness of 20 micrometers to 60 micrometers. 11 . The adsorption material as claimed in claim 8 , wherein the porous hollow fiber has an inner diameter of 300 micrometers to 600 micrometers, and the porous hollow fiber has a thickness of 80 micrometers to 150 micrometers. 12 . A method of lowering low-density lipoprotein cholesterol concentration in blood, comprising: bringing blood into contact with the adsorption material as claimed in claim 8 to lower low-density lipoprotein cholesterol concentration in the blood.
Lipoids · CPC title
by absorption (A61M1/3675 takes precedence) · CPC title
Polyethersulfones · CPC title
with monohydroxy compounds · CPC title
by esterified hydroxyl radicals · CPC title
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