Magnetic particle operation device
US-2021129158-A1 · May 6, 2021 · US
US2025319476A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2025319476-A1 |
| Application number | US-202419002883-A |
| Country | US |
| Kind code | A1 |
| Filing date | Dec 27, 2024 |
| Priority date | Dec 28, 2023 |
| Publication date | Oct 16, 2025 |
| Grant date | — |
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A magnetic substance separation device is configured for attracting magnetic substances in a sample within a sample container. The magnetic substance separation device includes a casing and at least one magnetic component assembly. The casing has at least one accommodation compartment. The at least one magnetic component assembly is disposed in the at least one accommodation compartment, and the at least one magnetic component assembly includes at least four cubic magnetic components. In addition, the at least four cubic magnetic components are linearly arranged with different magnetization directions, allowing magnetic field lines of the at least one magnetic component assembly to concentrate on one side, such that the at least one magnetic component assembly forms at least one strong magnetic surface on the casing. The at least one strong magnetic surface is configured to attract the magnetic substances in the sample within the sample container.
Opening claim text (preview).
What is claimed is: 1 . A magnetic substance separation device configured for attracting magnetic substances in a sample within a sample container, and the magnetic substance separation device comprising: a casing having at least one accommodation compartment; and at least one magnetic component assembly disposed in the at least one accommodation compartment, and the at least one magnetic component assembly comprising at least four cubic magnetic components; wherein the at least four cubic magnetic components are linearly arranged with different magnetization directions, allowing magnetic field lines of the at least one magnetic component assembly to concentrate on one side, such that the at least one magnetic component assembly forms at least one strong magnetic surface on the casing, and the at least one strong magnetic surface is configured to attract the magnetic substances in the sample within the sample container. 2 . The magnetic substance separation device according to claim 1 , wherein the at least four cubic magnetic components are arranged in Halbach array. 3 . The magnetic substance separation device according to claim 1 , wherein the at least one magnetic component assembly further forms a weak magnetic surface on the casing, and the weak magnetic surface and the at least one strong magnetic surface are located on opposite sides of the casing. 4 . The magnetic substance separation device according to claim 1 , wherein the at least one magnetic component assembly comprises a plurality of magnetic component assemblies, the at least one accommodation compartment comprises a plurality of accommodation compartments, and the plurality of magnetic component assemblies are respectively disposed in the plurality of accommodation compartments. 5 . The magnetic substance separation device according to claim 4 , wherein the at least four cubic magnetic components in one of the plurality of accommodation compartments are arranged in alignment or in an offset configuration relative to the at least four cubic magnetic components in another of the plurality of accommodation compartments. 6 . The magnetic substance separation device according to claim 4 , wherein each two adjacent cubic magnetic components within the same accommodation compartment are in physical contact with each other. 7 . The magnetic substance separation device according to claim 4 , wherein the casing has a plurality of partitions, the plurality of partitions are respectively disposed between two adjacent accommodation compartments, a thickness of each of the plurality of partitions ranges from 1.0 mm to 10.0 mm, and a thickness of the casing at the at least one strong magnetic surface ranges from 1.0 mm to 10.0 mm. 8 . The magnetic substance separation device according to claim 1 , wherein the at least one magnetic component assembly is in physical contact with an inner peripheral surface of the at least one accommodation compartment. 9 . The magnetic substance separation device according to claim 1 , wherein a side length of each cubic magnetic component ranges from 1 mm to 15 mm. 10 . The magnetic substance separation device according to claim 1 , further comprising a holder disposed on the casing, wherein the holder is configured to secure the sample container onto the at least one strong magnetic surface of the casing. 11 . The magnetic substance separation device according to claim 10 , wherein the holder includes a central post disposed in a central region of the at least one strong magnetic surface, the sample container is a flexible tube, and the central post is configured for the sample container to be wound around. 12 . The magnetic substance separation device according to claim 11 , wherein the holder further comprises a cover disposed on the casing, forming an accommodation space between the cover and the at least one strong magnetic surface, the cover has a first passage hole and a second passage hole that are connected to the accommodation space, the central post is disposed to pass through the cover, the central post has a winding groove, the first passage hole is configured for the sample container to pass through and extend into the accommodation space, the winding groove is located in the accommodation space and configured for the sample container to be wound around, and the second passage hole is configured for the sample container to pass through and extend out of the accommodation space. 13 . The magnetic substance separation device according to claim 1 , wherein the at least one magnetic component assembly comprises a plurality of magnetic component assemblies, the at least one accommodation compartment comprises a plurality of accommodation compartments, and the plurality of magnetic component assemblies are respectively disposed in the plurality of accommodation compartments; and wherein the plurality of accommodation compartments are configured in a dual-layer arrangement, the at least one strong magnetic surface comprises two strong magnetic surfaces, and the two strong magnetic surfaces are located on opposite surfaces of the casing. 14 . The magnetic substance separation device according to claim 13 , wherein the casing is plate-shaped, the sample container is a flexible tube, and the casing is configured for the sample container to be wound around. 15 . The magnetic substance separation device according to claim 1 , wherein the casing is cylindrical, the casing has an outer peripheral surface, the at least one accommodation compartment is arranged near the outer peripheral surface, and the at least one strong magnetic surface is located on the outer peripheral surface of the casing. 16 . The magnetic substance separation device according to claim 15 , wherein the sample container is a flexible tube, and the casing is configured for the sample container to be wound around. 17 . The magnetic substance separation device according to claim 15 , further comprising a holder, wherein the holder is disposed on the casing, and the holder is configured to secure the sample container onto the at least one strong magnetic surface of the casing; and wherein the holder is a quick-release outer cover, the holder comprises a support base and at least one extension arm, the support base is detachably disposed on an end surface of the casing, the at least one extension arm is connected to the support base and suspended above the at least one strong magnetic surface, the sample container is a flexible tube, and the at least one extension arm is configured for the sample container to be wound around. 18 . The magnetic substance separation device according to claim 1 , wherein the casing is cylindrical, the casing has an inner peripheral surface, the at least one accommodation compartment is arranged near the inner peripheral surface, and the at least one strong magnetic surface is located on the inner peripheral surface of the casing. 19 . The magnetic substance separation device according to claim 18 , further comprising a holder, wherein the inner peripheral surface of the casing surrounds and forms an accommodation space, and the holder is configured to secure the sample container onto the at least one strong magnetic surface of the casing; and wherein the holder is a quick-release shaft, the holder is detachably disposed in the accommodation space, the sample container is a flexible tube, and the holder is configured for the sample container to be wound around.
acting directly on the substance being separated · CPC title
acting on the medium containing the substance being separated, e.g. magneto-gravimetric-, magnetohydrostatic-, or magnetohydrodynamic separation · CPC title
Holders integrated in container to position an object · CPC title
Flexible containers without fluid transport within · CPC title
Open gradient magnetic separators, i.e. separators in which the gap is unobstructed, characterised by the configuration of the gap · CPC title
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