Hydration solutions containing volatile solutions and medical device products including the same
US-12201750-B2 · Jan 21, 2025 · US
US2025242088A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2025242088-A1 |
| Application number | US-202519071069-A |
| Country | US |
| Kind code | A1 |
| Filing date | Mar 5, 2025 |
| Priority date | Nov 13, 2020 |
| Publication date | Jul 31, 2025 |
| Grant date | — |
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Catheter assemblies including an interfacial pH controller for maintaining hydration liquid pH are provided.
Opening claim text (preview).
1 . A catheter assembly comprising: a catheter with at least a portion of the catheter having a hydrophilic surface; a sleeve associated with an interfacial pH controller and surrounding at least a section of an outer surface of the catheter; and a hydration liquid at least partially in contact with the interfacial pH controller. 2 . The catheter assembly of claim 1 , wherein the interfacial pH controller is embedded within at least one layer of the sleeve. 3 . The catheter assembly of claim 1 , wherein the interfacial pH controller is coated onto a surface of the sleeve. 4 . The catheter assembly of claim 1 , wherein the interfacial pH controller is a salt. 5 . The catheter assembly of claim 4 , wherein the solubility of the salt is less than 0.005 wt % at 25° C. in water, preferably less than 0.003 wt % at 25° C. 6 . The catheter assembly claim 4 , wherein the salt is comprised of an inorganic salt. 7 . The catheter assembly of claim 4 , wherein the salt includes an alkaline earth metal. 8 . The catheter assembly of claim 7 , wherein the alkaline earth metal is calcium or magnesium. 9 . The catheter assembly of claim 8 , wherein the alkaline earth metal is calcium. 10 . The catheter assembly of claim 4 , wherein the salt includes an anion. 11 . The catheter assembly of claim 10 , wherein the anion is carbonate or phosphate. 12 . The catheter assembly of claim 11 , wherein the anion is carbonate. 13 . The catheter assembly of claim 4 , wherein the salt is calcium carbonate. 14 . The catheter assembly of claim 8 , wherein the salt is magnesium carbonate. 15 . The catheter assembly of claim 9 , wherein the salt is calcium phosphate. 16 . The catheter assembly of claim 1 , wherein the sleeve is a film. 17 . The catheter assembly of claim 16 , wherein the film includes a polymer. 18 . The catheter assembly of claim 17 , wherein the polymer is polyethylene or polyurethane. 19 . The catheter assembly of claim 1 , wherein the pH of the hydration liquid with the interfacial pH controller is from about 4.5 to 8.0, preferably 6.0 to about 7.5. 20 . The catheter assembly of claim 1 , wherein the hydration liquid is within the sleeve and in contact with the hydrophilic surface.
multi-layered, e.g. coated (coating materials A61L29/08) · CPC title
Packages specially adapted therefor (combined with means for introducing catheters, e.g. dispensers, A61M25/0113); catheter kit packages (for surgical articles A61B50/30) · CPC title
Materials for lubricating medical devices · CPC title
Inorganic materials other than carbon · CPC title
Phosphorus-containing compounds, e.g. phosphates, phosphonates · CPC title
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