Method of recovering and reusing phosphoric acid from fermentation broth or fermentation waste liquid

Patent metadata

Field	Value
Publication number	US-2025236522-A1
Application number	US-202318849211-A
Country	US
Kind code	A1
Filing date	Mar 20, 2023
Priority date	Mar 24, 2022
Publication date	Jul 24, 2025
Grant date	—

Abstract

Provided are a method of recovering phosphoric acid in the form of ammonium phosphate or a hydrate thereof from a fermentation broth or a waste liquid thereof, and/or a method of reusing the recovered phosphoric acid in fermentation.

First claim

1 : A method of recovering phosphoric acid from a fermentation broth or a fermentation waste liquid, the method comprising the steps of:
(a) concentrating a phosphoric acid-containing fermentation broth or fermentation waste liquid; (b) adjusting pH of the concentrated solution to 8 to 11 by adding ammonia gas or an ammonia solution to the concentrated solution; and (c) separating ammonium phosphate or a hydrate thereof from the pH-adjusted concentrated solution.

2 : A method of reusing phosphoric acid from a fermentation broth or fermentation waste liquid, the method comprising the steps of:
(a) concentrating a phosphoric acid-containing fermentation broth or fermentation waste liquid; (b) adjusting pH of the concentrated solution to 8 to 11 by adding ammonia gas or an ammonia solution to the concentrated solution; (c) separating ammonium phosphate or a hydrate thereof from the pH-adjusted concentrated solution; and (d) adding the ammonium phosphate or the hydrate thereof to a medium.

3 : The method of claim 1 , wherein the ammonium phosphate is diammonium hydrogen phosphate.

4 : The method of claim 1 , wherein the fermentation broth comprises (i) O-phosphoserine, (ii) O-phosphohomoserine, or (iii) an amino acid or derivative thereof, prepared by adding O-phosphoserine or O-phosphohomoserine, a converting enzyme or a microorganism expressing the same, and a sulfide.

5 : The method of claim 1 , further comprising a step of cooling the pH-adjusted concentrated solution, and/or a step of adding a crystal of ammonium phosphate or a hydrate thereof as a crystal nucleus between step (b) and step (c), or in step (c).

6 : The method of claim 1 , further comprising a step of cooling the pH-adjusted concentration solution, and/or a step of adding a crystal of ammonium phosphate or a hydrate thereof as a crystal nucleus between step (b) and step (c), or in step (c).

7 : The method of claim 1 , wherein the hydrate is diammonium hydrogen phosphate heptahydrate or diammonium hydrogen phosphate dodecahydrate.

8 : The method of claim 1 , further comprising a step of crystallizing the ammonium phosphate or the hydrate thereof of step (c) from a mother liquor.

9 : The method of claim 8 , wherein step (c) comprises (i) a step of concentrating a mother liquor, (ii) a step of adjusting pH of the mother liquor to 8 to 11, and (iii) a step of crystallizing ammonium phosphate or the hydrate thereof from the pH-adjusted mother liquor and separating the same.

10 : The method of claim 9 , further comprising a step of adding a crystal of the ammonium phosphate or the hydrate thereof as a crystal nucleus to the mother liquor between step (ii) and step (iii) or in step (iii).

11 : The method of claim 1 , further comprising a step of adjusting pH of the fermentation broth or the fermentation waste liquid to 8 to 11, before step (a).

12 : The method of claim 1 , further comprising a step of adding an alcohol in step (b); or between step (b) and step (c).

13 : The method of claim 12 , wherein the alcohol is methanol, ethanol, propanol, butanol, or a combination thereof.

14 : The method of claim 2 , wherein the ammonium phosphate is diammonium hydrogen phosphate.

15 : The method of claim 2 , wherein the fermentation broth comprises (i) O-phosphoserine, (ii) O-phosphohomoserine, or (iii) an amino acid or derivative thereof, prepared by adding O-phosphoserine or O-phosphohomoserine, a converting enzyme or a microorganism expressing the same, and a sulfide.

16 : The method of claim 2 , wherein the hydrate is diammonium hydrogen phosphate heptahydrate or diammonium hydrogen phosphate dodecahydrate.

Assignees

• Cj Cheiljedang Corp

Inventors

• Lee Kang Hoon
• Lee Seung-Je
• Kim Jun-Woo
• Kim Jaeik
• Lee In Sung
• Jung Jun Young

Classifications

• C01B25/28 Primary

  Ammonium phosphates · CPC title

• C01B25/234 Primary

  Purification; Stabilisation; Concentration (purification concomitant with preparation C01B25/22; preparation involving solvent-solvent extraction C01B25/46) · CPC title

• C05B7/00

  Fertilisers based essentially on alkali or ammonium orthophosphates (C05B11/00 takes precedence) · CPC title

• C12P3/00 Primary

  Preparation of elements or inorganic compounds except carbon dioxide {(recovery of carbon dioxides as by-products C12F3/02)} · CPC title