System and method for compounding medication
US-2015374585-A1 · Dec 31, 2015 · US
US2025221892A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2025221892-A1 |
| Application number | US-202519096304-A |
| Country | US |
| Kind code | A1 |
| Filing date | Mar 31, 2025 |
| Priority date | Nov 25, 2015 |
| Publication date | Jul 10, 2025 |
| Grant date | — |
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A syringe for delivery of liquid to a container has a body with proximal end, a frustoconical distal end, and a cylindrical sidewall extending a longitudinal axis. The syringe includes a nozzle at a distal portion of the syringe, the nozzle having a throughbore providing fluid communication between an interior volume of the syringe and a medical connector configured to be connected to the nozzle. The nozzle includes a plurality of longitudinal ribs formed on an inner surface of the nozzle. The plurality of longitudinal ribs directs a flow of a medical fluid along an inner surface of the frustoconical distal end and along an interior surface of the cylindrical sidewall of the syringe under a Coandă effect. Syringe and methods for reducing a number of bubbles formed in a medical fluid during a syringe filling procedure are described.
Opening claim text (preview).
What is claimed is: 1 . A method for reducing a number of bubbles formed in a fluid during a syringe filling procedure, the method comprising: flowing the fluid past through a central bore of a nozzle of a syringe; flowing the fluid past a plurality of longitudinal ribs formed on an inner surface of the nozzle and extending radially inward from the inner surface; diverting the fluid by in a radially outward direction toward an angled portion of an inner surface of a frustoconical distal end of the syringe; inducing a Coandă effect in the fluid by the diverting and flowing steps such that the number of bubbles formed during the syringe filling procedure in reduced compared to a filling procedure that does not include the diverting and flowing steps; flowing the fluid down the inner surface of the frustoconical distal end of the syringe; flowing the fluid down an interior surface of a cylindrical sidewall of the syringe, wherein the sidewall extends between the frustoconical distal end and a proximal end; and filling an interior volume of the syringe with the fluid. 2 . The method of claim 1 , wherein the plurality of longitudinal ribs induce the diverting of the fluid in the radially outward direction. 3 . The method of claim 1 , wherein the fill rate of the syringe is increased compared to a fill rate of a syringe without the plurality of longitudinal ribs. 4 . The method of claim 1 , wherein flowing the fluid past a plurality of longitudinal ribs formed on the inner surface of the nozzle and extending radially inward from the inner surface comprises flowing the fluid between a plurality of longitudinal channels between the plurality of longitudinal ribs. 5 . The method of claim 1 , wherein the plurality of longitudinal ribs comprises a plurality of longitudinal ribs having rounded edges. 6 . The method of claim 1 , wherein the plurality of longitudinal ribs comprises a plurality of longitudinal ribs having orthogonal edges. 7 . The method of claim 1 , wherein the plurality of longitudinal ribs are configured to enhance a surface adhesion of the fluid to the inner surface of the frustoconical distal end of the syringe. 8 . A syringe for a powered fluid injector, the syringe comprising: a proximal end, a frustoconical distal end, and a cylindrical sidewall extending between the proximal end and the distal end; a nozzle at a distal portion of the frustoconical distal end of the syringe, the nozzle having a throughbore providing fluid communication between an interior volume of the syringe and a connector configured to be connected to the nozzle; and a plurality of longitudinal ribs formed on an inner surface of the nozzle and extending radially inward from the inner surface of the nozzle; wherein the plurality of longitudinal ribs directs a flow of a fluid along the inner surface of the frustoconical distal end and along an interior surface of the cylindrical sidewall of the syringe under a Coandă effect as the syringe is being filled with the fluid. 9 . The syringe of claim 8 , wherein the plurality of longitudinal ribs are configured to enhance a surface adhesion of the fluid to the inner surface of the frustoconical distal end. 10 . The syringe of claim 8 , wherein the fluid flows between a plurality of longitudinal channels between the plurality of longitudinal ribs. 11 . A method for filing a syringe with a fluid, the method comprising: flowing the fluid past through a central bore of a nozzle of a syringe; flowing the fluid past a plurality of longitudinal ribs formed on an inner surface of the nozzle and extending radially inward from the inner surface; diverting the fluid by in a radially outward direction toward an angled portion of an inner surface of a frustoconical distal end of the syringe; inducing a Coandă effect in the fluid by the flowing and diverting steps such that the number of bubbles formed during the syringe filling procedure in reduced compared to a filling procedure that does not include the diverting and flowing steps; flowing the fluid down the inner surface of the frustoconical distal end of the syringe; flowing the fluid down an interior surface of a cylindrical sidewall of the syringe, wherein the sidewall extends between the frustoconical distal end and a proximal end; and filling an interior volume of the syringe with the fluid. 12 . The method of claim 11 , wherein flowing the fluid past a plurality of longitudinal ribs formed on the inner surface of the nozzle and extending radially inward from the inner surface comprises flowing the fluid between a plurality of longitudinal channels between the plurality of longitudinal ribs. 13 . The method of claim 11 , further comprising enhancing a surface adhesion of the fluid to the inner surface of the frustoconical distal end of the syringe.
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