Configuration for ultra high pressure electrolytic eluent generators

Patent metadata

Field	Value
Publication number	US-2025198019-A1
Application number	US-202519071106-A
Country	US
Kind code	A1
Filing date	Mar 5, 2025
Priority date	Dec 30, 2021
Publication date	Jun 19, 2025
Grant date	—

Abstract

An electrolytic eluent generator includes an electrolyte reservoir and at least one eluent generation cartridge. The electrolyte reservoir includes a chamber containing an aqueous electrolyte solution; and a first electrode. The at least one eluent generation cartridge includes a platinum mesh electrode; a polymer screen; a plurality of reinforced membranes; a membrane washer; and a spacer including a central post and an annular projection.

First claim

What is claimed is:

1 . An ion chromatography system comprising:
a pump; a chromatographic separation column; a detector; and an electrolytic eluent generator comprising:
an electrolyte reservoir including:
a chamber containing an aqueous electrolyte solution; and
a first electrode;

at least one eluent generation cartridge including:
a platinum mesh electrode;
a polymer screen;
a plurality of reinforced membranes;
a membrane washer including at least one ion exchange membrane; and
a spacer including a central post and an annular projection,
wherein the membrane washer is deformable into an annular space between the annular projection and the central post during compression such that a gap is formed between the membrane washer and the adjacent ion exchange membrane.

2 . The ion chromatography system of claim 1 , wherein the eluent generation cartridge is configured to operate at a pressure of at least about 5,000 psi.

3 . The ion chromatography system of claim 2 , wherein the eluent generation cartridge is configured to operate at a pressure of at least about 10,000 psi.

4 . The ion chromatography system of claim 2 , wherein the eluent generation cartridge is configured to operate at a pressure of not greater than about 30,000 psi.

5 . The ion chromatography system of claim 4 , wherein the eluent generation cartridge is configured to operate at a pressure of not greater than about 15,000 psi.

6 . The ion chromatography system of claim 1 , wherein the plurality of reinforced membranes includes at least 5 ion exchange membranes.

7 . The ion chromatography system of claim 6 , wherein the plurality of reinforced membranes includes not more than about 100 ion exchange membranes.

8 . The ion chromatography system of claim 1 , wherein the membrane washer includes not more than about 20 ion exchange membranes.

9 . The ion chromatography system of claim 1 , wherein the aqueous electrolyte solution includes potassium hydroxide or sodium hydroxide.

10 . The ion chromatography system of claim 1 , wherein the aqueous electrolyte solution includes methanesulfonic acid.

11 . A method of preparing an eluent for an ion chromatography system:
suppling a liquid to an electrolytic eluent generator, the electrolytic eluent generator including an electrolyte reservoir and at least one eluent generation cartridge, the electrolyte reservoir including a chamber containing an aqueous electrolyte solution and a first electrode, the at least one eluent generation cartridge including a second electrode, a plurality of reinforced membranes, a membrane washer including at least one ion exchange membrane, and a spacer including a central post and an annular projection, wherein the membrane washer is deformable into an annular space between the annular projection and the central post during compression such that a gap is formed between the membrane washer and the adjacent ion exchange membrane; apply a current between the first electrode and the second electrode to cause the migration of ions from the electrolyte reservoir, through the at least one ion exchange membrane, and into the liquid to form an eluent; and providing the eluent to a chromatographic separation column.

12 . The method of claim 11 , wherein the eluent generation cartridge is configured to operate at a pressure of at least about 5,000 psi.

13 . The method of claim 12 , wherein the eluent generation cartridge is configured to operate at a pressure of at least about 10,000 psi.

14 . The method of claim 12 , wherein the eluent generation cartridge is configured to operate at a pressure of not greater than about 30,000 psi.

15 . The method of claim 14 , wherein the eluent generation cartridge is configured to operate at a pressure of not greater than about 15,000 psi.

16 . The method m of claim 11 , wherein the plurality of reinforced membranes includes at least 5 ion exchange membranes.

17 . The method of claim 16 , wherein the plurality of reinforced membranes includes not more than about 100 ion exchange membranes.

18 . The method of claim 11 , wherein the membrane washer includes not more than about 20 ion exchange membranes.

19 . The method of claim 11 , wherein the aqueous electrolyte solution includes potassium hydroxide or sodium hydroxide.

20 . The method of claim 11 , wherein the aqueous electrolyte solution includes methanesulfonic acid.

Assignees

• Dionex Corp

Inventors

• Lu Zhongqing
• Rubero Angelo
• Liu Yan
• Lin Rong

Classifications

• C25B1/16

  Hydroxides (by simultaneous production of alkali metal hydroxides and chlorine, oxyacids or salts of chlorine C25B1/34) · CPC title

• G01N2030/965

  suppressor columns · CPC title

• G01N30/96 Primary

  using ion-exchange (G01N30/02, G01N30/90 take precedence) · CPC title

• C25B13/02

  characterised by shape or form · CPC title

• B01D15/426

  Specific type of solvent · CPC title