Antimicrobial compositions

Patent metadata

Field	Value
Publication number	US-2025134790-A1
Application number	US-202218681256-A
Country	US
Kind code	A1
Filing date	Aug 11, 2022
Priority date	Aug 17, 2021
Publication date	May 1, 2025
Grant date	—

Abstract

Described herein are methods and compositions that can be applied to personal cleaning, oral care, deodorant and hard surface cleaning applications, including liquid soap, foaming soap, liquid dishwashing detergent, shower gel, shampoo, emulsified deodorant, mouthwash, toothpaste and facial cleanser, in order to reduce or eliminate microbes on a surface or body part.

First claim

1 . An antimicrobial composition comprising:
a. a perfume ingredient having a bactericidal effect of a 5.5 log reduction in an ethanol solution at a concentration of less than or equal to 0.1% in ethanol solution; b. a surfactant; and c. a hydrotrope.

2 . The antimicrobial composition of claim 1 , wherein the perfume ingredient is at least 0.001% (w/v) of the antimicrobial composition.

3 . The antimicrobial composition of claim 1 , wherein the surfactant is selected from the group consisting of: an anionic surfactant, a non-ionic surfactant, an amphoteric surfactant, and a combination thereof.

4 . The antimicrobial composition of claim 1 , wherein the anionic surfactant is sodium lauryl ether sulfate, the amphoteric surfactant is cocamidopropyl betaine, and the non-ionic surfactant is coco-glucoside.

5 . The antimicrobial composition of claim 1 , wherein the antimicrobial composition comprises less than 4% hydrotrope.

6 . The antimicrobial composition according to claim 5 , wherein the hydrotrope is selected from the group consisting of: short chain alkyl polyglycosides, toluene sulfonate, xylene sulfonate, cumene sulfonate, diisobutyl sulfosuccinate, sodium salicylate, sodium acetate, and a combination thereof; or wherein the hydrotrope is a sodium, ammonium or potassium salt of a hydrotrope selected from the group consisting of: toluene sulfonate, xylene sulfonate, cumene sulfonate, diisobutyl sulfosuccinate; dipropyleneglycol n-butyl ether;
and a combination thereof.

7 . The antimicrobial composition of claim 1 , wherein the antimicrobial composition further comprises an additional agent active against gram-positive or gram-negative bacteria.

8 . The antimicrobial composition of claim 1 , wherein the antimicrobial composition further comprises a chelating agent selected from the group consisting of EDTA, and CDTA, and a combination thereof.

9 . The antimicrobial composition of claim 1 , wherein the perfume ingredient is selected from the group consisting of: 1-phenylethyl acetate, 1-octanol, (1,3,3-trimethylbicyclo[2.2.1]heptan-2-ol, undecanal, (2E)-2-methyl-3-phenyl-2-propenal, (Z)-2-nonenal, 1-(5-propyl-1,3-benzodioxol-2-yl)ethenone, (2E,6Z)-2,6-nonadien-1-ol, ethyl benzoate, 1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol, benzyl butanoate, 1-butoxycarbonylethyl butanoate, ethyl hexanoate, 5-isopropyl-2-methylphenol, (4E,8E)-4,8-cyclododecadien-1-one, (4E,8Z)-4,8-cyclododecadien-1-one, (4Z,8E)-4,8-cyclododecadien-1-one, methyl (2E)-2-methyl-2-hexenoate, ethyl (E)-3-phenyl-2-propenoate, methyl (E)-3-phenyl-2-propenoate, (Z)-3,7-dimethyl-2,6-octadienal, (E)-3,7-dimethyl-2,6-octadienal, 3,5,5-trimethyl-1-hexanol, 3-[4-methyl-3-cyclohexen-1-yl]-1-butanol, (2E)-2-ethyl-4-[2,2,3-trimethyl-3-cyclopenten-1-yl]-2-buten-1-ol, 4-decanolide, (Z)-4-decenal, 2-methoxy-4-propylphenol, 2,6-dimethyl-7-octen-4-one, 2,6-dimethyl-4-heptanol, (E)-3,7-dimethyl-2,6-octadien-1-ol, 2,4,6-trimethyl-3-cyclohexene-1-methanol, 2-methoxy-4-[(1E)-1-propen-1-yl]phenol, (2E)-2-methyl-3-(4-methylphenyl)-2-propen-1-ol, 2,5-dimethyl-2-indanmethanol, 1,2-dimethoxy-4-[(1Z)-1-propen-1-yl]benzene, 1,2-dimethoxy-4-[(1E)-1-propen-1-yl]benzene, (4E)-4-methyl-5-(4-methylphenyl)-4-pentenal, (2,2-dimethyl-3-[(2Z)-3-methyl-2,4-pentadien-1-yl]oxirane, (2,2-dimethyl-3-[(2E)-3-methyl-2,4-pentadien-1-yl]oxirane, 2-ethyl-1-hexanol, (Z)-3,7-dimethyl-2,6-octadien-1-ol, 1-(3-methyl-1-benzofuran-2-yl)ethenone, (Z)-6-nonen-1-ol, (2E,6Z)-2,6-nonadienal, 1,8-p-menthadien-7-ol, 3-methyl-5-phenyl-1-pentanol, 2,6,6-trimethyl-1,3-cyclohexadiene-1-carbaldehyde, ethyl 2-hydroxybenzoate, 2-(5,5,6-trimethylbicyclo[2.2.1]hept-2-yl)-1-cyclohexanol, 3-(5,5,6-trimethylbicyclo [2.2.1]hept-2-yl)-1-cyclohexanol, 4-(5,5,6-trimethylbicyclo[2.2.1]hept-2-yl)-1-cyclohexanol, 2-(1,7,7-trimethylbicyclo[2.2.1]hept-2-yl)-1-cyclohexanol, 3-methylindole, 8-mercapto-3-p-menthanone, 3,7-dimethyl-3-octanol, 1,3,3-trimethylbicyclo[2.2.1]heptan-2-one, 1-isopropyl-4-methylbicyclo[3.1.0]hexan-3-one, 1-isopropyl-4-methylbicyclo [3.1.0] hexan-3-one, thymol, 6-hexyltetrahydro-2H-pyran-2-one, 3-propylphenol, 2-cyclohexylethyl acetate, octanal, 1,3-nonanediyl diacetate, tetrahydro-3-pentyl-4 (2H)-pyranyl acetate, 5-heptyldihydro-2 (3H)-furanone, 3-butylidene-1-benzo[C] furanone, 3,7-dimethyl-6-octen-1-ol, 3,7-dimethyl-6-octenenitrile, coriander oil, cyclopropylmethyl (3Z)-3-hexenoate, cyclopropylmethyl (3E)-3-hexenoate, 3,7-dimethyl-1-octen-3-ol, cinnamon leaf oil, 4-decanolide, 3,5,6-trimethyl-3-cyclohexene-1-carbaldehyde, 2,4,6-trimethyl-3-cyclohexene-1-carbaldehyde, Lavandin Sumian essential oil, peppermint oil, 3,6,7-trimethyl-2,6-octadienal, petitgrain paraguay essential oil, (2Z)-4,8-dimethyl-2,7-nonadien-4-ol, and a combination thereof

10 . The antimicrobial composition of claim 1 , wherein the perfume ingredient is selected from the group consisting of: (4E,8E)-4,8-cyclododecadien-1-one, (4E,8Z)-4,8-cyclododecadien-1-one, (4Z,8E)-4,8-cyclododecadien-1-one, (4E)-4-methyl-5-(4-methylphenyl)-4-pentenal, 3,7-dimethyl-6-octenenitrile, 3,7-dimethyl-6-octen-1-ol, (2Z)-4,8-dimethyl-2,7-nonadien-4-ol, 1,3-nonanediyl diacetate, tetrahydro-3-pentyl-4(2H)-pyranyl acetate, (Z)-4-decenal, 3-[4-methyl-3-cyclohexen-1-yl]-1-butanol, undecanal, (2E)-2-ethyl-4-[2,2,3-trimethyl-3-cyclopenten-1-yl]-2-buten-1-ol, 3,7-dimethyl-3-octanol, 2-(5,5,6-trimethylbicyclo[2.2.1]hept-2-yl)-1-cyclohexanol, 3-(5,5,6-trimethylbicyclo[2.2.1]hept-2-yl)-1-cyclohexanol, 4-(5,5,6-trimethylbicyclo[2.2.1]hept-2-yl)-1-cyclohexanol, 2-(1,7,7-trimethylbicyclo[2.2.1]hept-2-yl)-1-cyclohexanol, 2-cyclohexylethyl acetate, 1,3,3-trimethylbicyclo[2.2.1]heptan-2-one, 1-isopropyl-4-methylbicyclo[3.1.0]hexan-3-one, and a combination thereof.

11 . The antimicrobial composition of claim 1 , wherein the perfume ingredient is selected from the group consisting of: cyclopropylmethyl (3Z)-3-hexenoate or cyclopropylmethyl (3E)-3-hexenoate, 3,6,7-trimethyl-2,6-octadienal, (2Z)-4,8-dimethyl-2,7-nonadien-4-ol, octanal, 5-heptyldihydro-2 (3H)-furanone, 3,7-dimethyl-6-octen-1-ol, 3,7-dimethyl-6-octenenitrile, 3,7-dimethyl-1-octen-3-ol, cinnamon leaf oil, Lavandin Sumian essential oil, 2-cyclohexylethyl acetate, peppermint oil, coriander oil, Petitgrain paraguay essential oil, 3-butylidene-1-benzo[C] furanone, and a combination thereof.

12 . The antimicrobial composition according to claim 1 , further comprising a solvent and/or a water-miscible co-solvent.

13 . The antimicrobial composition according to claim 1 , further comprising ingredients selected from the group consisting of colorants, preservatives, viscosifiers, opacifiers, emollients, humectants, antioxidants, gelling agents, gums, chelators, functional polymers, cellulose derivatives, essential oils, electrolytes, and pH adjusters.

14 . The antimicrobial composition of claim 1 , further comprising a malodor neutralizing system and/or a malodor antagonist system.

15 . A consumer product comprising the antimicrobial composition according to claim 1 , wherein the consumer product is selected from the group consisting of: a hair care product, a body care product, a skin care product, an oral care product, a female care product, a home care product, a laundry care product, a body cleansing product, shampoo, shower gel, facial cleanser, shaving gel, liquid hand soap, foaming soap, hand sanitizer, soap bar, mouthwash, toothpaste, female hygiene composition, fabric cleanser, carpet cleanser, all-purpose cleanser, dishwashing detergent, fresh produce detergent, deodorant, air fresher, and air disinfectant.

16 . A method for eliminating or/and reducing the number of microbes on a surface or body part, the

Assignees

• Firmenich & Cie

Inventors

• Huang Yang
• Ma Qiu-Min
• Fieber Wolfgang

Classifications

• A61K8/463

  containing sulfuric acid derivatives, e.g. sodium lauryl sulfate · CPC title

• A01P1/00

  Disinfectants; Antimicrobial compounds or mixtures thereof · CPC title

• A01N65/36

  Rutaceae [Rue family], e.g. lime, orange, lemon, corktree or pricklyash · CPC title

• A01N65/10

  Apiaceae or Umbelliferae [Carrot family], e.g. parsley, caraway, dill, lovage, fennel or snakebed · CPC title

• A01N65/24

  Lauraceae [Laurel family], e.g. laurel, avocado, sassafras, cinnamon or camphor · CPC title