Oxygenator and extracorporeal membrane oxygenation device

Patent metadata

Field	Value
Publication number	US-2025099661-A1
Application number	US-202318471673-A
Country	US
Kind code	A1
Filing date	Sep 21, 2023
Priority date	Sep 21, 2023
Publication date	Mar 27, 2025
Grant date	—

Abstract

Disclosed are an oxygenator and an extracorporeal membrane oxygenation device. The oxygenator includes a housing; an oxygenation chamber, arranged in the housing, and having a blood flow pipeline extend through a blood inlet and a blood outlet; a partition plate, arranged between the housing and the oxygenation chamber, the partition plate is arranged in a same direction as the upper end cover and divide the interior of the housing into a heat medium chamber and a gas chamber. The oxygenator combines the design of a heat medium chamber and a gas chamber to perform brand-new optimization design on a blood flow path, a gas pipeline and a heat medium pipeline of a membrane lung, so as to obtain the best hemodynamic performance, uniform distribution of internal flow fields and pressure fields, small flow retention zone, low blood flow resistance and high gas blood exchange efficiency and heat exchange efficiency.

First claim

What is claimed is:

1 . An oxygenator, comprising:
a housing ( 100 ), provided with an upper end cover ( 600 ) and a lower end cover ( 700 ) arranged opposite to each other, wherein the upper end cover ( 600 ) is connected to the lower end cover ( 700 ) via a side wall, a blood inlet ( 110 ) is arranged at a center of the upper end cover ( 600 ), and a blood outlet ( 120 ) is arranged at one end of the lower end cover ( 700 ) of the housing ( 100 ) close to the side wall; an oxygenation chamber ( 200 ), arranged in the housing ( 100 ), wherein blood is fed into the oxygenation chamber ( 200 ) through the blood inlet ( 110 ), and the blood oxygenated is discharged through the blood outlet ( 120 ); and a partition plate ( 300 ), arranged between the housing ( 100 ) and the oxygenation chamber ( 200 ), wherein the partition plate ( 300 ) is arranged in a same direction as the upper end cover ( 600 ), and divides an interior of the housing ( 100 ) into a heat medium chamber ( 400 ) and a gas chamber ( 500 ).

2 . The oxygenator according to claim 1 , wherein
the side wall of the housing ( 100 ) is provided with a heat medium inlet ( 130 ) and a heat medium outlet ( 140 ), a heat medium is fed into the heat medium chamber ( 400 ) through the heat medium inlet ( 130 ), and the heat medium subjected to heat exchange is discharged through the heat medium outlet ( 140 ).

3 . The oxygenator according to claim 2 , wherein
an interior of the heat medium chamber ( 400 ) is further provided with a first isolation part ( 410 ) and a second isolation part ( 420 ), and the first isolation part ( 410 ) and the second isolation part ( 420 ) separate the heat medium chamber ( 400 ) into a first heat medium chamber ( 430 ) and a second heat medium chamber ( 440 ); the first heat medium chamber ( 430 ) is communicated with the heat medium inlet ( 130 ), and the second heat medium chamber ( 440 ) is communicated with the heat medium outlet ( 140 ); the first heat medium chamber ( 430 ) is communicated with the second heat medium chamber ( 440 ) via a heat medium pipeline, and the heat medium pipeline extends through the oxygenation chamber ( 200 ).

4 . The oxygenator according to claim 3 , wherein
the first isolation part ( 410 ) is arranged between the housing ( 100 ) and the oxygenation chamber ( 200 ) and at a side close to the blood outlet ( 120 ); the second isolation part ( 420 ) is arranged between the housing ( 100 ) and the oxygenation chamber ( 200 ) and at a side away from the blood outlet ( 120 ); the first isolation part ( 410 ) and the second isolation part ( 420 ) divide the heat medium chamber ( 400 ) into the first heat medium chamber ( 430 ) and a second heat medium chamber ( 440 ) having a same size.

5 . The oxygenator according to claim 4 , wherein
the heat medium inlet ( 130 ) and the heat medium outlet ( 140 ) are arranged on one end of the side wall of the housing ( 100 ) close to the blood outlet ( 120 ); the oxygenation chamber ( 200 ) is of a quadrangular prism structure, and two opposite side surfaces of the oxygenation chamber ( 200 ) are connected via the heat medium pipeline.

6 . The oxygenator according to claim 1 , wherein
the side wall of the housing ( 100 ) is provided with a gas inlet ( 150 ) and a gas outlet ( 160 ), an oxygen-containing gas is fed into the gas chamber ( 500 ) through the gas inlet ( 150 ), and the gas subjected to gas blood exchange is exhausted through the gas outlet ( 160 ).

7 . The oxygenator according to claim 6 , wherein
an interior of the gas chamber ( 500 ) is provided with a third isolation part ( 510 ) and a fourth isolation part ( 520 ), and the third isolation part ( 510 ) and the fourth isolation part ( 520 ) separate the gas chamber ( 500 ) into a first gas chamber ( 530 ) and a second gas chamber ( 540 ); the first gas chamber ( 530 ) is communicated with the gas inlet ( 150 ), and the second gas chamber ( 540 ) is communicated with the gas outlet ( 160 ). the first gas chamber ( 530 ) is communicated with the second gas chamber ( 540 ) via a gas pipeline, and the gas pipeline extends through the oxygenation chamber ( 200 ).

8 . The oxygenator according to claim 7 , wherein
the third isolation part ( 510 ) and the fourth isolation part ( 520 ) are respectively arranged at both ends of the gas chamber ( 500 ); the third isolation part ( 510 ) and the fourth isolation part ( 520 ) divide the gas chamber ( 500 ) into the first gas chamber ( 530 ) and a second gas chamber ( 540 ) having a same size.

9 . The oxygenator according to claim 8 , wherein
the gas inlet ( 150 ) is arranged on one end of the side wall of the housing ( 100 ) away from the blood outlet ( 120 ); the gas outlet ( 160 ) is arranged on one end, close to the blood outlet ( 120 ) of the side wall of the housing ( 100 ) close to the blood outlet ( 120 ); the oxygenation chamber ( 200 ) is of a quadrangular prism structure, and two opposite side surfaces of the oxygenation chamber ( 200 ) are connected via the gas pipeline.

10 . The oxygenator according to claim 2 , wherein
the side wall of the housing ( 100 ) is provided with a gas inlet ( 150 ) and a gas outlet ( 160 ), an oxygen-containing gas is fed into the gas chamber ( 500 ) through the gas inlet ( 150 ), and the gas subjected to gas blood exchange is exhausted through the gas outlet ( 160 ).

11 . The oxygenator according to claim 3 , wherein
the side wall of the housing ( 100 ) is provided with a gas inlet ( 150 ) and a gas outlet ( 160 ), an oxygen-containing gas is fed into the gas chamber ( 500 ) through the gas inlet ( 150 ), and the gas subjected to gas blood exchange is exhausted through the gas outlet ( 160 ).

12 . The oxygenator according to claim 4 , wherein
the side wall of the housing ( 100 ) is provided with a gas inlet ( 150 ) and a gas outlet ( 160 ), an oxygen-containing gas is fed into the gas chamber ( 500 ) through the gas inlet ( 150 ), and the gas subjected to gas blood exchange is exhausted through the gas outlet ( 160 ).

13 . The oxygenator according to claim 5 , wherein
the side wall of the housing ( 100 ) is provided with a gas inlet ( 150 ) and a gas outlet ( 160 ), an oxygen-containing gas is fed into the gas chamber ( 500 ) through the gas inlet ( 150 ), and the gas subjected to gas blood exchange is exhausted through the gas outlet ( 160 ).

14 . An extracorporeal membrane oxygenation device, comprising the oxygenator according to claim 1 .

15 . The extracorporeal membrane oxygenation device according to claim 14 , wherein
the side wall of the housing ( 100 ) is provided with a heat medium inlet ( 130 ) and a heat medium outlet ( 140 ), a heat medium is fed into the heat medium chamber ( 400 ) through the heat medium inlet ( 130 ), and the heat medium subjected to heat exchange is discharged through the heat medium outlet ( 140 ).

16 . The extracorporeal membrane oxygenation device according to claim 15 , wherein
an interior of the heat medium chamber ( 400 ) is further provided with a first isolation part ( 410 ) and a second isolation part ( 420 ), and the first isolation part ( 410 ) and the second isolation part ( 420 ) separate the heat medium chamber ( 400 ) into a first heat medium chamber ( 430 ) and a second heat medium chamber ( 440 ); the first heat medium chamber ( 430 ) is communicated with the heat medium inlet ( 130 ), and the second heat medium chamber ( 440 ) is communicated with the heat medium outlet ( 140 ); the first heat medium chamber ( 430 ) is communicated with the second heat medium chamber ( 440 ) via a heat m

Assignees

• Beijing Aerospace Changfeng Co Ltd
• Univ Beihang

Inventors

• Su Zihua
• Xu Mingzhou
• Yue Minghao
• Li Jinian
• Wang Yawei
• Lin Shihang
• Fan Yubo
• Chen Zengsheng
• Liu Huichao
• Zhang Shiyao
• Cheng Yake
• Li Jinyu
• Yu Wenjie

Classifications

• A61M1/1629

  with integral heat exchanger · CPC title

• A61M2206/20

  having means for promoting or enhancing the flow, actively or passively · CPC title

• A61M2205/366

  by liquid heat exchangers · CPC title

• A61M1/1698 Primary

  Blood oxygenators with or without heat-exchangers (intracorporal A61M1/1678; manufacturing of membranes therefor B01D67/00; semi-permeable membranes for separation processes characterised by their properties B01D69/00; semi-permeable membranes characterised by their material B01D71/00) · CPC title

• A61M1/1621

  Constructional aspects thereof (semi-permeable membranes for separation processes characterised by their properties B01D69/00; semi permeable membranes characterised by their material B01D71/00) · CPC title