Tri-Axis Accelerometers for Patient Physiologic Monitoring and Closed Loop Control of Implantable Ventricular Assist Devices

Patent metadata

Field	Value
Publication number	US-2025090835-A1
Application number	US-202418959115-A
Country	US
Kind code	A1
Filing date	Nov 25, 2024
Priority date	May 26, 2022
Publication date	Mar 20, 2025
Grant date	—

Abstract

Blood circulation assist systems include a ventricular assist device (VAD), a remote accelerometer, and a controller that controls operation of the VAD based on output of the remote accelerometer. A blood circulation assist system includes a VAD, a controller, and a remote accelerometer. The VAD includes an impeller. The remote accelerometer is configured to generate a remote accelerometer output indicative of accelerations measured by the remote accelerometer. The implanted controller controls a rotation speed of the impeller based on the remote accelerometer output.

First claim

1 - 45 . (canceled)

46 . A blood circulation assist system, comprising:
a ventricular assist device (VAD) comprising an inlet, an outlet, an impeller, and a motor stator operable to rotate the impeller to pump a blood flow, wherein the inlet is configured for coupling with a ventricle of a patient to receive the blood flow from the ventricle, wherein the outlet is configured for coupling with a blood vessel of the patient to transfer the blood flow to the blood vessel; and a controller configured to process a remote accelerometer output indicative of accelerations of the patient at a remote accelerometer location and control a rotation speed of the impeller based on the remote accelerometer output; and a remote accelerometer configured to generate the remote accelerometer output, wherein the remote accelerometer is configured to be implanted in the patient at the remote accelerometer location, and wherein the remote accelerometer location is separated from the VAD to isolate the remote accelerometer from noise generated by the VAD.

47 . The system of claim 46 , wherein the remote accelerometer is configured for implantation in a pectoral region of the patient or abdominal wall region of the patient.

48 . The system of claim 46 , wherein:
the VAD further comprises power transistors that are used to control supply of electrical currents to windings of the motor stator; and the remote accelerometer location is separated from the VAD to isolate the remote accelerometer from electrical switching noise generated by the power transistors.

49 . The system of claim 46 , wherein the controller is configured to:
process the remote accelerometer output to determine a heart rate of the patient; and control the rotation speed of the impeller based on the heart rate.

50 . The system of claim 46 , wherein the controller is configured to process the remote accelerometer output to determine a valve opening timing of the patient.

51 . The system of claim 46 , wherein the controller is configured to process the remote accelerometer output to monitor for a valve disorder of the patient.

52 . The system of claim 46 , wherein the controller is configured to process the remote accelerometer output to determine a respiration rate of the patient.

53 . The system of claim 46 , wherein the controller is configured to process the remote accelerometer output to monitor for an occurrence of pump thrombosis in the VAD, an occurrence of an occlusion in the VAD, and/or an occurrence of an instability of the impeller.

54 - 55 . (canceled)

56 . The system of claim 46 , wherein the controller is configured to process the remote accelerometer output to monitor an orientation of the patient.

57 - 61 . (canceled)

62 . The system of claim 46 , wherein the controller is configured to process the remote accelerometer output to monitor for a fall of the patient.

63 . (canceled)

64 . The system of claim 46 , wherein the controller is configured to process the remote accelerometer output to determine whether the patient is active or at rest.

65 . The system of claim 46 , wherein the controller is configured to process the remote accelerometer output to determine a wellness indicator for the patient.

66 . The system of claim 46 , wherein:
the controller is configured to process the remote accelerometer output to detect a cardiac cycle timing of the patient; the cardiac cycle timing comprises a heart rate and a time of occurrence for each of one or more cardiac cycle events; and the controller is configured to vary the rotation speed of the impeller in sync with the cardiac cycle timing.

67 . (canceled)

68 . The system of claim 66 , wherein the controller is configured to:
process the remote accelerometer output to detect a time of occurrence of at least one heart sound; and detect the cardiac cycle timing based on the time of occurrence of the at least one heart sound.

69 . The system of claim 68 wherein the at least one heart sound comprises:
a sound of closure of at least one atrioventricular valve of the patient; and/or
a sound of closure of at least one semilunar valve of the patient.

70 . The system of claim 66 , wherein the controller is configured to vary the rotation speed of the impeller over a target cardiac cycle based on detected timing of one or more cardiac cycles that occur prior to the target cardiac cycle and/or the detected timing of the target cardiac cycle.

71 . (canceled)

72 . The system of claim 66 , wherein the controller is configured to:
process the remote accelerometer output to measure an activity level of the patient; and control the rotation speed of the impeller based on the activity level.

73 . The system of claim 72 , wherein the controller is configured to process the remote accelerometer output to measure a respiration rate for the patient and/or a diaphragm contraction for the patient, and base the activity level on the respiration rate and/or the diaphragm contraction.

74 . The system of claim 46 , wherein the controller is configured to:
process the remote accelerometer output to measure an activity level of the patient; and control the rotation speed of the impeller based on the activity level.

75 . The system of claim 74 , wherein the controller is configured to:
process the remote accelerometer output to measure a respiration rate and/or a diaphragm contraction; and base the activity level on the respiration rate and/or the diaphragm contraction.

76 . (canceled)

Assignees

• Tc1 Llc

Inventors

• Harjes Daniel I
• Anderson Russell
• Toutam Pritika
• Kimball Brian

Classifications

• A61M2230/63

  Motion, e.g. physical activity · CPC title

• A61M2230/62

  Posture · CPC title

• A61M2230/42

  Rate · CPC title

• A61M2230/06

  Heartbeat rate only · CPC title

• A61M2205/50

  with microprocessors or computers · CPC title