Single molecule genome-wide mutation and fragmentation profiles of cell-free dna
US-2025131982-A1 · Apr 24, 2025 · US
US2025077888A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2025077888-A1 |
| Application number | US-202318459803-A |
| Country | US |
| Kind code | A1 |
| Filing date | Sep 1, 2023 |
| Priority date | Sep 1, 2023 |
| Publication date | Mar 6, 2025 |
| Grant date | — |
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Predicting local layout effects using a variational autoencoder with integrated regression and classification network including identifying a vector of features and a vector of output metrics from a dataset; performing basic training of a neural network machine learning variational autoencoder (VAE) combined with a regression network using the vector of features and the vector of output targets constrained to a latent space of the VAE; performing interpolation training of the VAE and combined regression network; determining a set of influential features of an integrated circuit layout based on an input gradient using an output of the VAE and combined regression network with interpolation training; using the set of influential features as input into a parallel neural network to generate a function for each influential feature; and creating a compact model to calculate local layout effects based on the functions for each influential feature.
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What is claimed is: 1 . A method for predicting local layout effects using a variational autoencoder with integrated regression and classification network, the method comprising: identifying a dataset from a database of integrated circuit layouts of integrated circuits and electrical measurements of the integrated circuits; identifying a vector of features and a vector of output metrics from the dataset; performing basic training of a neural network machine learning variational autoencoder (VAE) combined with a regression network using the vector of features and the vector of output targets constrained to a latent space of the VAE; performing interpolation training of the VAE and combined regression network using the vector of features and the vector of output metrics to generate interpolated vectors for interpolation training; determining a set of influential features of an integrated circuit layout based on an input gradient using an output of the VAE and combined regression network with interpolation training; using the set of influential features as input into a parallel neural network to generate a function for each influential feature; and creating a compact model to calculate local layout effects based on the functions for each influential feature. 2 . The method of claim 1 , further comprising: determining that the influential features of the integrated circuit layout are within a domain of training data points in latent space by examining a location of a test data point relative to training data points in the latent space. 3 . The method of claim 1 , wherein the integrated circuit layout is a layer of an integrated circuit design. 4 . The method of claim 1 , wherein the compact model is based on a sum of the functions for each influential feature. 5 . The method of claim 1 , wherein the functions for each influential feature are magnitudes of effects on an electrical parameter. 6 . The method of claim 1 , wherein the local layout effects comprise one from a group consisting of threshold voltage, drive current, circuit power, and circuit delay. 7 . The method of claim 1 , wherein the local layout effects comprise one from a group consisting of yield, defectively, measured line width, and measured space. 8 . An apparatus for predicting local layout effects using a variational autoencoder with integrated regression and classification network, the apparatus comprising: a computer processor; and a computer memory operatively coupled to the computer processor, the computer memory having disposed within it computer program instructions that, when executed by the computer processor, cause the apparatus to: identifying a dataset from a database of integrated circuit layouts of integrated circuits and electrical measurements of the integrated circuits; identifying a vector of features and a vector of output metrics from the dataset; performing basic training of a neural network machine learning variational autoencoder (VAE) combined with a regression network using the vector of features and the vector of output targets constrained to a latent space of the VAE; performing interpolation training of the VAE and combined regression network using the vector of features and the vector of output metrics to generate interpolated vectors for interpolation training; determining a set of influential features of an integrated circuit layout based on an input gradient using an output of the VAE and combined regression network with interpolation training; using the set of influential features as input into a parallel neural network to generate a function for each influential feature; and creating a compact model to calculate local layout effects based on the functions for each influential feature. 9 . The apparatus of claim 8 , wherein the computer program instructions further cause the apparatus to carry out the step of: determining that the influential features of the integrated circuit layout are within a domain of training data points in latent space by examining a location of a test data point relative to training data points in the latent space. 10 . The apparatus of claim 8 , wherein the integrated circuit layout is a layer of an integrated circuit design. 11 . The apparatus of claim 8 , wherein the compact model is based on a sum of the functions for each influential feature. 12 . The apparatus of claim 8 , wherein the functions for each influential feature are magnitudes of effects on an electrical parameter. 13 . The apparatus of claim 8 , wherein the local layout effects comprise one from a group consisting of threshold voltage, drive current, circuit power, and circuit delay. 14 . The apparatus of claim 8 , wherein the local layout effects comprise one from a group consisting of yield, defectively, measured line width, and measured space. 15 . A computer program product for predicting local layout effects using a variational autoencoder with integrated regression and classification network, the computer program product disposed upon a computer readable medium, the computer program product comprising computer program instructions that, when executed, cause a computer to: identify a dataset from a database of integrated circuit layouts of integrated circuits and electrical measurements of the integrated circuits; identify a vector of features and a vector of output metrics from the dataset; perform basic training of a neural network machine learning variational autoencoder (VAE) combined with a regression network using the vector of features and the vector of output targets constrained to a latent space of the VAE; perform interpolation training of the VAE and combined regression network using the vector of features and the vector of output metrics to generate interpolated vectors for interpolation training; determine a set of influential features of an integrated circuit layout based on an input gradient using an output of the VAE and combined regression network with interpolation training; use the set of influential features as input into a parallel neural network to generate a function for each influential feature; and create a compact model to calculate local layout effects based on the functions for each influential feature. 16 . The computer program product of claim 15 , wherein the computer program instructions further cause the apparatus to carry out the step of: determining that the influential features of the integrated circuit layout are within a domain of training data points in latent space by examining a location of a test data point relative to training data points in the latent space. 17 . The computer program product of claim 15 , wherein the integrated circuit layout is a layer of an integrated circuit design. 18 . The computer program product of claim 15 , wherein the compact model is based on a sum of the functions for each influential feature. 19 . The computer program product of claim 15 , wherein the functions for each influential feature are magnitudes of effects on an electrical parameter. 20 . The computer program product of claim 15 , wherein the local layout effects comprise one from a group consisting of threshold voltage. drive current, circuit power, and circuit delay.
Non-supervised learning, e.g. competitive learning · CPC title
Probabilistic or stochastic networks · CPC title
Combinations of networks · CPC title
Distributed learning, e.g. federated learning · CPC title
Auto-encoder networks; Encoder-decoder networks · CPC title
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