Medical liquid composition for aerial administration
US-2024358636-A1 · Oct 31, 2024 · US
US2025072472A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2025072472-A1 |
| Application number | US-202418812401-A |
| Country | US |
| Kind code | A1 |
| Filing date | Aug 22, 2024 |
| Priority date | Aug 31, 2023 |
| Publication date | Mar 6, 2025 |
| Grant date | — |
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Provided is a nicotine pouch filler including nicotine, a release control excipient, a binder, a pH adjuster, and a flavoring agent, in which a content of the binder is 6 to 10 wt % with respect to a weight of total solid contents of the nicotine pouch filler.
Opening claim text (preview).
What is claimed is: 1 . A nicotine pouch filler comprising: nicotine; a release control excipient; a binder; a pH adjuster; and a flavoring agent, wherein a content of the binder is 6 to 10 wt % with respect to a weight of total solid contents of the nicotine pouch filler. 2 . The nicotine pouch filler of claim 1 , wherein the binder comprises at least one or more selected from a group consisting of Povidone K-25, hydroxypropyl cellulose, low-substituted hydroxypropyl cellulose, hydroxypropylmethyl cellulose (HPMC), and carboxymethylcellulose (CMC). 3 . The nicotine pouch filler of claim 1 , wherein the nicotine comprises nicotine salt, and the nicotine salt comprises at least one or more selected from a group consisting of nicotine salt benzoate, nicotine salt tartrate, nicotine salt malate, and nicotine salt salicylate. 4 . The nicotine pouch filler of claim 1 , wherein the release control excipient comprises one or more selected from a group consisting of cellulose and sugar alcohol. 5 . The nicotine pouch filler of claim 4 , wherein the cellulose comprises one or more of microcrystalline cellulose and methyl cellulose. 6 . The nicotine pouch filler of claim 4 , wherein the sugar alcohol comprises at least one or more selected from a group consisting of erythritol, xylitol, mannitol, sorbitol, maltitol, and isomalt. 7 . The nicotine pouch filler of claim 1 , wherein the pH adjuster comprises at least one or more selected from a group consisting of sodium bicarbonate and sodium carbonate. 8 . The nicotine pouch filler of claim 1 , wherein pH of the nicotine pouch filler is 8.3 to 8.5. 9 . The nicotine pouch filler of claim 1 , wherein the nicotine pouch filler comprises particles with a size of 150 to 300 μm. 10 . The nicotine pouch filler of claim 1 , wherein the nicotine pouch filler has nicotine elution performance of 20% or more within 8 minutes, and nicotine elution performance of 70% or more within 30 minutes. 11 . A nicotine pouch comprising: a nicotine pouch filler; and a packaging material, wherein the nicotine pouch filler comprises: nicotine; a release control excipient; a binder; a pH adjuster; and a flavoring agent, and wherein a content of the binder is 6 to 10 wt % with respect to a weight of total solid contents of the nicotine pouch filler. 12 . A method of preparing a nicotine pouch filler, the method comprising: step S 1 of mixing at least one or more selected from a group consisting of nicotine, a release control excipient, a binder, a pH adjuster, and a flavoring agent; step S 2 of spraying a solvent; and step S 3 of performing granulation, wherein, in step S 1 , a content of the binder is 6 to 10 wt % with respect to a weight of total solid contents of the nicotine pouch filler.
by organic and inorganic substances {(A24B15/281 takes precedence)} · CPC title
by acyclic compounds · CPC title
Plant extracts other than tobacco · CPC title
by organic substances {(A24B15/281 takes precedence)} · CPC title
by inorganic substances only · CPC title
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