Slide cleaning apparatus and method

Patent metadata

Field	Value
Publication number	US-2025041912-A1
Application number	US-202218722806-A
Country	US
Kind code	A1
Filing date	Dec 22, 2022
Priority date	Dec 23, 2021
Publication date	Feb 6, 2025
Grant date	—

Abstract

An apparatus for removing contaminants from a slide comprises a manifold including at least one input port and at least one output port in fluid communication with the at least one input port, the at least one output port being adapted to direct a flow of gas onto a surface of the slide such that the flow of gas removes contaminants from the slide; an aperture for receiving the slide; and an enclosure adapted to capture the contaminants removed from the slide.

First claim

1 . An apparatus for removing contaminants from a slide, the apparatus comprising:
a manifold including at least one input port and at least one output port in fluid communication with the at least one input port, the at least one output port being adapted to direct a flow of gas onto a surface of the slide such that the flow of gas removes contaminants from the slide; an aperture for receiving the slide; and an enclosure adapted to capture the contaminants removed from the slide.

2 . The apparatus of claim 1 , wherein the enclosure is removably attachable to the apparatus.

3 . The apparatus of claim 1 , wherein the at least one output port comprises:
one or more nozzles each having a diameter of about 0.5 mm to about 1.5 mm; or one or more nozzles each having a diameter of about 1 mm.

4 . (canceled)

5 . The apparatus of claim 3 , wherein the at least one input port is adapted to removably receive a gas line.

6 . The apparatus of claim 5 , wherein the gas line is connected to a gas source being adapted to supply gas at a pressure of between about 40 KPa and about 60 KPa.

7 . The apparatus of claim 1 , wherein the enclosure is substantially P-shaped, with a basin of the P being adapted to capture the contaminants.

8 . The apparatus of claim 1 , wherein the enclosure includes at least one opening to allow for passage of the gas out of the enclosure.

9 . The apparatus of claim 8 , wherein the at least one opening contains a mesh configured to intercept particulate contaminates removed from the slide.

10 . The apparatus of claim 9 , wherein:
the mesh is comprised of apertures configured to intercept particles having a size greater than about 0.4 mm; and/or. the mesh is removable from the at least one opening of the enclosure; and/or the mesh is constructed of stainless steel or a polymer;

11 - 13 . (canceled)

14 . The apparatus of claim 1 , including a guide for guiding the slide into the enclosure.

15 . The apparatus of claim 14 , wherein the guide comprises opposing ledges or slots.

16 . The apparatus of claim 1 , further comprising a mounting means for mounting the apparatus within a sample processing instrument.

17 . The apparatus of claim 16 , wherein:
the mounting means comprises two or more recesses on the manifold configured to receive mounting projections within the sample processing instrument; or the mounting means comprises two or more projections on the manifold configured to cooperate with two or more recesses in a mounting surface within the sample processing instrument.

18 . (canceled)

19 . The apparatus of claim 1 , wherein the gas is ionized.

20 . (canceled)

21 . A method for removing contaminants from a slide, the method comprising the steps of:
inserting the slide into an enclosure of a slide-cleaning apparatus; applying a flow of gas at a predetermined pressure and/or flow rate to a first surface of the slide to remove contaminants; and removing the slide from the slide-cleaning apparatus.

22 . The method of claim 21 , further including the step of adjusting a height of the slide for insertion into the slide-cleaning apparatus.

23 . The method of claim 21 , wherein the predetermined pressure is between about 40 KPa and about 60 KPa.

24 . The method of claim 21 , wherein the method is performed within a sample processing instrument having a slide handling robot, and wherein the slide handling robot is configured to transfer the slide from a first location in the sample processing instrument into the slide-cleaning apparatus for removal of contaminants.

25 . The method of claim 24 , wherein the slide handling robot adjusts a height of the slide before insertion of the slide into the slide-cleaning apparatus, and removes the slide from the slide-cleaning apparatus after removal of the contaminants.

26 - 27 . (canceled)

28 . The method of claim 22 , further comprising the steps of, after applying the flow of gas to the first surface of the slide to remove contaminants, and before removing the slide from the slide-cleaning apparatus:
moving the slide in relation to the applied gas along a length of the slide, and; adjusting the height of the slide to a height to facilitate cleaning a second surface of the slide, by applying gas to the second surface of the slide.

29 - 33 . (canceled)

Assignees

• Leica Biosystems Melbourne Pty

Inventors

• Koifman Alex
• Dzitac Pavel
• Drummond Michael Houston

Classifications

• B08B6/00

  Cleaning by electrostatic means · CPC title

• B25J11/0085

  Cleaning · CPC title

• B08B2205/00

  Details of machines or methods for cleaning by the use of gas or air flow · CPC title

• B08B15/04

  from a small area, e.g. a tool {(removing chips B23Q11/0042)} · CPC title

• B08B11/02

  Devices for holding articles during cleaning {(B08B9/42 takes precedence)} · CPC title