Method to relieve stress in capsule shells to reduce propensity to break

Patent metadata

Field	Value
Publication number	US-2025025377-A1
Application number	US-202418908883-A
Country	US
Kind code	A1
Filing date	Oct 8, 2024
Priority date	Dec 8, 2016
Publication date	Jan 23, 2025
Grant date	—

Abstract

A method of treating a hard capsule shell to reduce or alleviate stress or reduce the propensity for cracking in the capsule shell. The method includes a step of heating at least a portion of the hard capsule shell to a temperature above a glass transition temperature of the capsule shell but below a melt temperature of the hard capsule shell for a time sufficient to reduce internal stress in the hard capsule shell. The method can be used to reduce cracking of hard capsule shells by application of the heat treatment to the filled capsule shells after fabrication and filling.

First claim

What is claimed is:

1 . A method to reduce the propensity of cracking in a completed hard capsule shell that encapsules a hygroscopic fill, comprising a step of:
heating a portion of the completed hard capsule shell to a temperature above a glass transition temperature of the completed capsule shell but 2° C.-10° C. below a melt temperature of the completed hard capsule shell,
wherein the completed hard capsule shell comprises gelatin and has a weight ratio of plasticizer to polymer of from 0 to 0.25.

2 . The method according to claim 1 , wherein the portion of the capsule shell is heated to 2° C.-7° C. below the melt temperature of the completed hard capsule shell.

3 . The method according to claim 1 , wherein the portion of the capsule shell is heated to 2° C.-3° C. below the melt temperature of the completed hard capsule shell.

4 . The method according to claim 1 , wherein the completed hard capsule shell comprises a cap portion and a body portion.

5 . The method according to claim 4 , wherein the portion of the completed hard capsule shell that is heated is the portion where the cap portion overlaps with the body portion.

6 . The method according to claim 1 , wherein the completed hard capsule shell is closed by fitting a cap portion of the hard capsule shell and a body portion of the hard capsule shell together.

7 . The method according to claim 1 , wherein a duration of the heating step is from 2 seconds to 24 hours.

8 . The method according to claim 1 , wherein the heating step is carried out at a relative humidity of less than 60%.

9 . The method according to claim 1 , wherein the heating step heats the entire completed hard capsule shell.

10 . The method according to claim 1 , wherein a duration of the heating step is from 1 hour to 12 hours.

11 . A method of treating a completed hard capsule shell that encapsules a hygroscopic fill, comprising a step of:
heating a portion of the completed hard capsule shell to a temperature above a glass transition temperature of the completed capsule shell but 2° C.-10° C. below a melt temperature of the completed hard capsule shell,
wherein the completed hard capsule shell comprises gelatin and has a weight ratio of plasticizer to polymer of from 0 to 0.25.

12 . The method according to claim 11 , wherein the portion of the capsule shell is heated to 2° C.-7° C. below the melt temperature of the completed hard capsule shell.

13 . The method according to claim 11 , wherein the portion of the capsule shell is heated to 2° C.-3° C. below the melt temperature of the completed hard capsule shell.

14 . The method according to claim 11 , wherein the completed hard capsule shell comprises a cap portion and a body portion.

15 . The method according to claim 14 , wherein the portion of the completed hard capsule shell that is heated is the portion where the cap portion overlaps with the body portion.

16 . The method according to claim 11 , wherein the completed hard capsule shell is closed by fitting a cap portion and a body portion together.

17 . The method according to claim 11 , wherein a duration of the heating step is from 2 seconds to 24 hours.

18 . The method according to claim 11 , wherein the heating step is carried out at a relative humidity of less than 60%.

19 . The method according to claim 11 . wherein the heating step heats the entire completed hard capsule shell.

20 . The method according to claim 1 , wherein a duration of the heating step is from 1 hour to 12 hours.

Assignees

• Scherer Technologies Llc R P

Inventors

• Fulper Lester David
• Hart Norton

Classifications

• F26B21/50

  Ducting arrangements from the source of air or other gases to the materials or objects being dried · CPC title

• F26B21/37

  Velocity of flow; Quantity of flow · CPC title

• F26B21/35 Primary

  Temperature; Pressure · CPC title

• F26B21/33

  Humidity · CPC title

• F26B21/25

  partly outside the drying enclosure · CPC title