High-throughput methodology for identifying rna-protein interactions transcriptome-wide
US-2015355173-A1 · Dec 10, 2015 · US
Compositions and methods for using fixed biological samples in partition-based assays
US2025003956A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2025003956-A1 |
| Application number | US-202418828673-A |
| Country | US |
| Kind code | A1 |
| Filing date | Sep 9, 2024 |
| Priority date | Dec 23, 2019 |
| Publication date | Jan 2, 2025 |
| Grant date | — |
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Abstract
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The present disclosure provides compositions and methods for using fixed biological samples in partition-based assays. In at least one embodiment, the disclosure provides a composition comprising a fixed biological sample and an un-fixing agent contained in a partition, such as a discrete droplet. In some embodiments, the disclosure provides un-fixing agent compounds capable of catalytically cleaving crosslinks in fixed biological samples, particularly crosslinked nucleic acids, such as RNA.
First claim
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What is claimed is: 1 . A composition comprising a compound selected from compound (8), compound (9), compound (10), or a combination thereof:
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acting on peptide bonds (3.4) · CPC title
acting on peptide bonds (3.4) · CPC title
having three or more double bonds between ring members or between ring members and non-ring members · CPC title
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- What does patent US2025003956A1 cover?
- The present disclosure provides compositions and methods for using fixed biological samples in partition-based assays. In at least one embodiment, the disclosure provides a composition comprising a fixed biological sample and an un-fixing agent contained in a partition, such as a discrete droplet. In some embodiments, the disclosure provides un-fixing agent compounds capable of catalytically cl…
- Who is the assignee on this patent?
- 10X Genomics Inc
- What technology area does this patent fall under?
- Primary CPC classification G01N33/5308. Mapped technology areas include Physics.
- When was this patent published?
- Publication date Thu Jan 02 2025 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).