Eyedrops for ameliorating or preventing retinal circulation disorder and retinal neurovascular coupling disorder

US2024415796A1 · US · A1

Patent metadata
FieldValue
Publication numberUS-2024415796-A1
Application numberUS-202118253096-A
CountryUS
Kind codeA1
Filing dateNov 19, 2021
Priority dateNov 19, 2020
Publication dateDec 19, 2024
Grant date

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

Eyedrops for ameliorating retinal circulation disorder and retinal neurovascular coupling disorder, the eyedrops containing fibrate-containing nanoparticles.

First claim

Opening claim text (preview).

1 . An eyedrop for ameliorating or preventing retinal circulation disorder and a retinal neurovascular coupling disorder, the eyedrop comprising nanoparticles including a fibrate, wherein the nanoparticles are a wet-ground product of a fibrate, and the nanoparticles have a particle diameter in the range of 10 to 300 nm. 2 . (canceled) 3 . The eyedrop according to claim 1 , further comprising a thickener. 4 . The eyedrop according to claim 3 , wherein the thickener is a cellulose-based thickener. 5 . The eyedrop according to claim 4 , wherein the cellulose-based thickener is methylcellulose. 6 . The eyedrop according to claim 1 , further comprising cyclodextrins. 7 . The eyedrop according to claim 6 , wherein the cyclodextrins are 2-hydroxypropyl-β-cyclodextrin. 8 . The method for ameliorating or preventing retinal circulation disorder or retinal neurovascular coupling disorder, the method comprising administering the eyedrop comprising nanoparticles including a fibrate to a subject, wherein the nanoparticles are a wet-ground product of a fibrate, and the nanoparticles have a particle diameter in the range of 10 to 300 nm. 9 . The method according to claim 8 , wherein the eyedrop further comprises a thickener. 10 . The method according to claim 9 , wherein the thickener is a cellulose-based thickener. 11 . The method according to claim 10 , wherein the cellulose-based thickener is methylcellulose. 12 . The method according to claim 8 , wherein the eyedrop further comprises cyclodextrins. 13 . The method according to claim 12 , wherein the cyclodextrins are 2-hydroxypropyl-β-cyclodextrin.

Assignees

Inventors

Classifications

  • Cyclodextrins; Derivatives thereof · CPC title

  • Cellulose; Derivatives thereof · CPC title

  • Nanocapsules; {Nanoparticles; (nanotubes A61K9/0092; polymeric micelles A61K9/1075; polymersomes A61K9/1273; pure drug nanoparticles A61K9/14; drug nanoparticles with adsorbed surface modifiers A61K9/141; conjugates, e.g. between drug and non-active nanoparticles, A61K47/50; preparations for in vivo diagnosis A61K49/00; with radioactive substances A61K51/00)} · CPC title

  • Eye, e.g. artificial tears · CPC title

  • A61P27/02Primary

    Ophthalmic agents · CPC title

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What does patent US2024415796A1 cover?
Eyedrops for ameliorating retinal circulation disorder and retinal neurovascular coupling disorder, the eyedrops containing fibrate-containing nanoparticles.
Who is the assignee on this patent?
Univ Nihon, Univ Kinki
What technology area does this patent fall under?
Primary CPC classification A61P27/02. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Thu Dec 19 2024 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).