Inhibitors of tyk2
US-2024425484-A1 · Dec 26, 2024 · US
US2024408123A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2024408123-A1 |
| Application number | US-202218700603-A |
| Country | US |
| Kind code | A1 |
| Filing date | Oct 18, 2022 |
| Priority date | Oct 22, 2021 |
| Publication date | Dec 12, 2024 |
| Grant date | — |
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The present invention relates to a food composition comprising, in % by weight of the food composition on dry matter basis, i) nucleotides in an amount of at least about 0.05% and ii) oligosaccharides in an amount of at least about 0.1%, wherein said oligosaccharides are selected from xylo-oligosaccharides (XOS), fructo-oligosaccharides (FOS), galacto-oligosaccharides (GOS), and combinations thereof.
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1 . A food composition comprising, in % by weight of the food composition on dry matter basis, i) nucleotides in an amount of at least about 0.05% and ii) oligosaccharides in an amount of at least about 0.1%, wherein said oligosaccharides are selected from xylo-oligosaccharides (XOS), fructo-oligosaccharides (FOS), galacto-oligosaccharides (GOS), and combinations thereof. 2 . The food composition of claim 1 , comprising, in % by weight of the food composition on dry matter basis, i) nucleotides in an amount ranging from about 0.05% to about 0.5%, and ii) oligosaccharides in an amount ranging from about 0.1% to about 2%, wherein said oligosaccharides are selected from xylo-oligosaccharides (XOS), fructo-oligosaccharides (FOS), galacto-oligosaccharides (GOS), and combinations thereof. 3 . The food composition of claim 1 , comprising, in % by weight of the food composition on dry matter basis: (i) nucleotides in an amount ranging from about 0.05% to about 0.5%; (ii) xylo-oligosaccharides (XOS) in an amount ranging from about 0.1% to about 0.7%, and/or (iii) fructo-oligosaccharides (FOS) in an amount ranging from about 0.3% to about 1%. 4 . The food composition of claim 1 , wherein the nucleotides are from a source of nucleotides selected from a yeast extract or a fraction thereof. 5 . The food composition of claim 1 , wherein said nucleotides comprise a combination of pyrimidines and purines. 6 . The food composition of claim 1 , wherein the oligosaccharides are selected from xylo-oligosaccharides (XOS), fructo-oligosaccharides (FOS), and combinations thereof. 7 . The food composition of claim 1 , wherein said XOS comprise XOS composed of xylose units linked by β-(1,4) bonds, with a degree of polymerization (DP) ranging from 2 to 10. 8 . The food composition of claim 1 , further comprising vitamin E in an amount ranging from about 0.01% to about 0.1%, in % by weight of the food composition on dry matter basis. 9 . The food composition of claim 1 , wherein said food composition is a dry composition, a wet composition, or a semi-moist composition. 10 . The food composition of claim 1 , wherein the food composition is a medicament. 11 - 17 . (canceled) 18 . The food composition of claim 4 , wherein the yeast extract is selected from a Kluyveromyces yeast extract or a Saccharomyces cerevisae yeast extract, or a fraction thereof. 19 . The food composition of claim 7 , wherein said FOS comprise at least about 50% of short-chain fructo-oligosaccharides (scFOS) in % by weight of the FOS in the food composition on dry matter basis. 20 . The food composition of claim 1 , further comprising beta-carotene in an amount ranging from about 0.0001% to about 0.001%, in % by weight of the food composition on dry matter basis. 21 . The food composition of claim 1 , further comprising arginine in an amount ranging from about 0.1% to about 10%, in % by weight of the food composition on dry matter basis. 22 . The food composition of claim 9 , wherein said food composition is a dry composition. 23 . A method for improving the immune function of a companion animal, comprising administering to the companion animal a food composition comprising, in % by weight of the food composition on dry matter basis, i) nucleotides in an amount of at least about 0.05% and ii) oligosaccharides in an amount of at least about 0.1%, wherein said oligosaccharides are selected from xylo-oligosaccharides (XOS), fructo-oligosaccharides (FOS), galacto-oligosaccharides (GOS), and combinations thereof. 24 . The method of claim 23 , wherein the immune function is selected from: cytokine production and antibody response to a vaccine, the immune response to an antigen, and combinations. 25 . A method for preventing or treating immune deficiency in a companion animal, comprising administering to the companion animal a food composition comprising, in % by weight of the food composition on dry matter basis, i) nucleotides in an amount of at least about 0.05% and ii) oligosaccharides in an amount of at least about 0.1%, wherein said oligosaccharides are selected from xylo-oligosaccharides (XOS), fructo-oligosaccharides (FOS), galacto-oligosaccharides (GOS), and combinations thereof.
characterised by the immunostimulating additives, e.g. chemical adjuvants · CPC title
Saccharomycetales, e.g. baker's yeast · CPC title
Immunostimulants · CPC title
Dry feed · CPC title
Colouring agents, e.g. pigmenting or dyeing agents · CPC title
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