Apparatus to treat tissue with pulsatile shear waves

Patent metadata

Field	Value
Publication number	US-2024407799-A1
Application number	US-202418752516-A
Country	US
Kind code	A1
Filing date	Jun 24, 2024
Priority date	Jun 30, 2014
Publication date	Dec 12, 2024
Grant date	—

Abstract

An apparatus is configured to provide hemostasis with tissue removal in order to inhibit one or more of blood loss or tissue drainage. In many embodiments, a nozzle releases a liquid jet in a liquid medium in order to provide cavitation and a plurality of shedding pulses. The liquid jet, its cavitation and the plurality of shedding pulses can affect vascular tissue in order to promote clotting in order to inhibit bleeding. In many embodiments, vessels of the vascular tissue are affected at a distance from a region where cavitation of the water jet contacts the tissue. In many embodiments, the cavitation and plurality of shedding pules are related to a pulsatile shear wave propagating along the blood vessel that is related to clot promoting changes of the blood vessel.

First claim

1 . (canceled)

2 . An apparatus to treat tissue, the apparatus comprising,
a pump; a nozzle coupled to the pump, the nozzle sized for immersion in a liquid and configured to generate a plurality of pulsatile shear waves to treat the tissue; and circuitry coupled to the pump to control fluid flow through the nozzle to treat the tissue with the plurality of pulsatile shear waves.

3 . The apparatus of claim 2 , wherein the pump provides a flow rate through the nozzle and the nozzle is configured to provide the plurality of pulsatile shear waves to a cut profile at a distance from the nozzle.

4 . The apparatus of claim 2 , wherein the nozzle is configured to be arranged with the tissue at a distance no more than a threshold transition distance from the tissue.

5 . The apparatus of claim 2 , wherein the nozzle is configured to be arranged with the tissue at a distance greater than a threshold transition distance from the tissue.

6 . The apparatus of claim 2 , wherein the circuitry comprises a processor configured with instructions to treat the tissue with the nozzle, the processor coupled to a linkage to move the nozzle in response to the instructions, wherein the processor comprises instructions to remove the tissue with a tissue removal profile with the nozzle positioned at a distance no more than a threshold transition distance for selective tissue removal from a tissue removal profile.

7 . The apparatus of claim 2 , wherein the pump comprises a piston to deliver a plurality of pump pulses and wherein the nozzle and a flow rate of the pump are configured to provide a plurality of pump pulses and each of the plurality of pump pulses provides a plurality of shedding pulses.

8 . The apparatus of claim 2 , wherein each of a plurality of pump pulses generates the plurality of pulsatile shear waves.

9 . The apparatus of claim 2 , wherein the nozzle is configured to be arranged to be directed toward the tissue to be treated, wherein jet hydrodynamic parameters are configured to allow mechanical disruption of the tissue.

10 . The apparatus of claim 9 , wherein the jet hydrodynamic parameters comprise one or more of a fluid jet velocity or a shear stress field.

11 . The apparatus of claim 2 , wherein jet hydrodynamic parameters are configured to generate the plurality of pulsatile shear waves.

12 . The apparatus of claim 2 , wherein the pulsatile shear wave interacts with an affected location of the tissue and promotes hemostasis at the affected location.

13 . The apparatus of claim 2 , wherein the jet comprises a substantially abrasive jet in order to remove vessels and non-vascular tissue of the vascular tissue at similar rates.

14 . The apparatus of claim 2 , wherein the plurality of pulsatile shear waves is configured to remove the tissue along a removal profile and decrease bleeding at a distance from the removal profile.

Assignees

• Procept Biorobotics Corp

Inventors

• Aljuri Nikolai
• Karpman Edward
• Danek Chris

Classifications

• A61B2017/00172

  Pulse trains, bursts, intermittent continuous operation · CPC title

• A61B2017/00154

  pulsed · CPC title

• A61B2017/32032

  using cavitation of the fluid · CPC title

• A61B2018/00547

  Prostate · CPC title

• A61B2017/32035

  with gas or air · CPC title