Method and apparatus for performing single gating in positron emission tomograpy sytems

Patent metadata

Field	Value
Publication number	US-2024225585-A1
Application number	US-202318336807-A
Country	US
Kind code	A1
Filing date	Jun 16, 2023
Priority date	Jan 9, 2023
Publication date	Jul 11, 2024
Grant date	—

Abstract

A method for performing single gating in a positron emission tomography (PET) system includes: receiving list-mode data acquired by scanning an imaging object using the PET system, the list-mode data being affected by quasi-periodic motion of the imaging object; producing a plurality of vectors based on the received list-mode data; generating a reference vector based on the produced plurality of vectors; selecting, from the produced plurality of vectors, a set of vectors corresponding to a single gate, based on respective differences compared with the generated reference vector; and generating an image of the imaging object based on the selected set of vectors.

First claim

What is claimed is:

1 . A method for performing single gating in a positron emission tomography (PET) system, the method comprising:
receiving list-mode data acquired by scanning an imaging object using the PET system, the list-mode data being affected by quasi-periodic motion of the imaging object; producing a plurality of vectors based on the received list-mode data; generating a reference vector based on the produced plurality of vectors; selecting, from the produced plurality of vectors, a set of vectors corresponding to a single gate, based on respective differences compared with the generated reference vector; and generating an image of the imaging object based on the selected set of vectors.

2 . The method of claim 1 , wherein the generating step further comprises:
obtaining a motion waveform with respect to the quasi-periodic motion of the imaging object, the obtained motion waveform having a number of cycles, deriving, based on a predefined criterion, a first number of vectors from the produced plurality of vectors, each of the first number of vectors corresponding to one of the number of cycles of the obtained motion waveform, and calculating, as the generated reference vector, an average of the derived number of vectors.

3 . The method of claim 2 , wherein the deriving step further comprises:
identifying, as the derived first number of vectors, a second number of vectors from the produced plurality of vectors, each of the identified second number of vectors corresponding to a predetermined phase percentage within one of the number of cycles of the obtained motion waveform.

4 . The method of claim 2 , wherein the deriving step further comprises:
identifying, as the derived first number of vectors, a second number of vectors from the produced plurality of vectors, each of the second identified number of vectors corresponding to a smallest amplitude point within one of the number of cycles of the obtained motion waveform.

5 . The method of claim 2 , wherein the deriving step further comprises:
identifying, as the derived first number of vectors, a second number of vectors from the produced plurality of vectors, each of the second identified number of vectors corresponding to a point having a smallest derivative term within one of the number of cycles of the obtained motion waveform, the derivative term being a first-order derivative of the obtained motion waveform, a second-order derivative of the obtained motion waveform, or a combination thereof.

6 . The method of claim 1 , wherein the selecting step further comprises:
obtaining a count percentage (P %) indicating a ratio of a number of the selected set of vectors to a number of the produced plurality of vectors, and determining, as the selected set of vectors, a first P % of the produced plurality of vectors when ranked from smallest difference to largest difference, compared with the generated reference vector.

7 . The method of claim 6 , wherein the obtaining step further comprises:
receiving, as the obtained count percentage, a count percentage from a user of the PET system.

8 . The method of claim 6 , wherein the obtaining step further comprises:
sorting, based on the respective differences compared with the generated reference vector, the produced plurality of vectors to create a curve, the created curve representing a relationship between a count percentage of the produced plurality of vectors and a corresponding variation of the respective differences compared with the generated reference vector, identifying a turning point on the created curve, and deriving, as the obtained count percentage, a count percentage corresponding to the identified turning point on the created curve.

9 . The method of claim 2 , wherein the generating step further comprises:
generating multiple reference vector candidates based on multiple predefined criteria, obtaining a count percentage (P %) indicating a ratio of a number of the selected set of vectors to a number of the produced plurality of vectors, calculating, with respect to each of the multiple reference vector candidates, an averaged difference of a first P % of the produced plurality of vectors when ranked from smallest difference to largest difference, compared with the reference vector candidate, and determining, as the generated reference vector, one of the multiple reference vector candidates that has a smallest calculated averaged difference.

10 . The method of claim 1 , wherein the respective differences compared with the generated reference vector are calculated as one of:
a Euclidian distance compared with the generated reference vector, a covariance compared with the generated reference vector, a mean squared error (MSE) compared with the generated reference vector, and an L 1 norm distance compared with the generated reference vector.

11 . The method of claim 2 , wherein the producing step further comprises:
dividing the received list-mode data into a plurality of segments; and creating, as the produced plurality of vectors, a plurality vectors based on the divided plurality of segments.

12 . The method of claim 11 , wherein the creating step further comprises:
creating, as the produced plurality of vectors, a plurality of sinograms based on the divided plurality of segments.

13 . The method of claim 11 , wherein the creating step further comprises:
creating a plurality of sinograms based on the divided plurality of segments, and performing downsampling on the created plurality of sinograms to obtain downsampled plurality of sinograms, as the produced plurality of vectors.

14 . The method of claim 11 , wherein the creating step further comprises:
creating a plurality of sinograms based on the divided plurality of segments, and extracting, as the produced plurality of vectors, a plurality of latent vectors from the created plurality of sinograms.

15 . The method of claim 11 , wherein the creating step further comprises:
reconstructing, as the produced plurality of vectors, a plurality of images based on the divided plurality of segments.

16 . The method of claim 11 , wherein the creating step further comprises:
reconstructing a plurality of images based on the divided plurality of segments, and performing downsampling on the reconstructed plurality of images to obtain downsampled plurality of vectors, as the produced plurality of vectors.

17 . The method of claim 11 , wherein the creating step further comprises:
reconstructing a plurality of images based on the divided plurality of segments, and extracting, as the produced plurality of vectors, a plurality of latent vectors from the reconstructed plurality of images.

18 . The method of claim 2 , wherein the obtaining step further comprises:
estimating, as the obtained motion waveform, a motion waveform by analyzing the produced plurality of vectors, or receiving, as the obtained motion waveform, a waveform from a device measuring the quasi-periodic motion of the imaging object.

19 . The method of claim 1 , wherein the quasi-periodic motion of the imaging object is respiratory motion of the imaging object, or cardiac motion of the imaging object.

20 . An apparatus for performing single gating in a positron emission tomography (PET) system, the apparatus comprising:
processing circuitry configured to
receive list-mode data acquired by scanning an imaging object using the PET system, the list-mode data being affected by quasi-periodic motion of th

Assignees

• Univ California
• Canon Medical Systems Corp

Inventors

• Qi Wenyuan
• Yang Li
• Kolthammer Jeffrey
• Tsai Yu-Jung
• Asma Evren
• Iatrou Maria
• Qi Jinyi
• Li Tiantian

Classifications

• G06T12/10 Primary

  Image preprocessing, e.g. calibration, positioning of sources or scatter correction · CPC title

• G06T2211/412

  Dynamic · CPC title

• A61B6/037

  Emission tomography · CPC title

• A61B6/541 Primary

  involving acquisition triggered by a physiological signal · CPC title