Finishing Apparatus For A Spray Drying System

Patent metadata

Field	Value
Publication number	US-2024125551-A1
Application number	US-202318467130-A
Country	US
Kind code	A1
Filing date	Sep 14, 2023
Priority date	Sep 15, 2022
Publication date	Apr 18, 2024
Grant date	—

Abstract

The present invention includes a spray drying disposable device for use in a spray drying system. The disposable has a spray drying head and a plasma drying chamber. The head has a spray dry nozzle assembly in fluid communication with the plasma source and the pressurized aerosol gas source. The pressurized gas flows in a vortex pattern that atomizes plasma droplets in the chamber. The head also includes a plenum has uniform air pressure of the drying gas. A baffle plate forms the floor of the plenum having drying gas jets that supply drying gas to the chamber. The atomized plasma droplets evaporate in the presence of the drying gas emitted from the jets to obtain dried plasma particles and humid air. A capture filter captures the dried plasma particles and allows the humid air to pass. The humid air passes through the gas outlet and the exhaust port.

First claim

What is claimed is:

1 ) A spray drying finishing apparatus for converting a spray drying disposable having a spray drying head, a drying chamber, and dried plasma into a dried plasma unit having the dried plasma, the spray drying finishing apparatus comprising:
A) an impactor, when in use and when the spray drying disposable having spray dried plasma is attached, allows for the movement of the dried plasma within the drying chamber, B) a sealer that seals the spray dried plasma within a portion of the drying chamber to thereby create a dried plasma unit; and C) a separator which separates the plasma unit from the drying chamber.

2 ) The spray drying finishing apparatus of claim 1 , further comprising:
A) at least one rail; and B) a shuttle that is slidably attached to the rail.

3 ) The spray drying finishing apparatus of claim 1 , further comprising a shuttle that comprises:
A) a spray drying head receiver for securing the spray drying head of the spray drying disposable; B) a locator that aligns the spray drying head within the spray drying head receiver; C) upper stationary shuttle frame; D) lower movable shuttle frame having one or more positioning arrangements for receiving the outer edge of the spray drying disposable, and a gas outlet receiver.

4 ) The spray drying finishing apparatus of claim 1 , wherein the spray drying head receiver further comprising spring activated detents.

5 ) The spray drying finishing apparatus of claim 1 , further comprising a tensioner for stretching the spray drying disposable during sealing, separating or both.

6 ) The spray drying finishing apparatus of claim 5 , wherein the tensioner is mounted to the lower movable shuttle frame.

7 ) The spray drying finishing apparatus of claim 5 , wherein when in use, the tensioner interacts with a ramp on the sealer, separator, or both, whereby the spray drying disposable is stretched during sealing, separating, or both.

8 ) The spray drying finishing apparatus of claim 2 , wherein the shuttle slides along the rail with a guide, wherein the rail is fixed.

9 ) The spray drying finishing apparatus of claim 8 , wherein the shuttle slides along the rail using a lead screw and a motor.

10 ) The spray drying finishing apparatus of claim 1 , wherein the sealer comprises an impulse sealer, a heat sealer, electric heater, radio frequency sealer, or a combination thereof.

11 ) The spray drying finishing apparatus of claim 1 , wherein the separator comprises, cut wire or heat cutter or a combination thereof.

12 ) The spray drying finishing apparatus of claim 1 , wherein the impactor moves dried plasma within the spray drying disposable using mechanical force created electrically, pneumatically, or with magnets or an ultrasound source.

13 ) The spray drying finishing apparatus of claim 1 , wherein the impactor comprises magnets plate arrangement, a pneumatic cylinder plate arrangement, or combination thereof.

14 ) The spray drying finishing apparatus of claim 1 , further including one or more sensors for determining a location of the shuttle as it slides along the at least one rail.

15 ) The spray drying finishing apparatus of claim 3 , wherein the locator comprises a recess/projection arrangement, a complementing shape arrangement, a hook/receiver arrangement, a channel and groove arrangement, a latch and catch arrangement, or a combination thereof.

16 ) The spray drying finishing apparatus of claim 3 , wherein the one or more first positioning arrangements and the one or more second positioning arrangements comprises a pin and opening arrangement, a hook/receiver arrangement, channel and groove arrangement, a latch and catch arrangement or a combination thereof.

17 ) A method for converting a spray drying disposable into a dried plasma unit having the dried plasma, the spray drying disposable having a spray drying head, a drying chamber, and dried plasma, wherein the method uses a spray drying finishing apparatus that comprises an impactor, a sealer, and a separator; wherein the method comprises the steps of;
A) moving the dried plasma within the drying chamber; B) sealing a portion of the drying chamber to thereby create a dried plasma unit; and C) separating the plasma unit from the drying chamber.

18 ) The method of claim 17 , wherein moving the dried plasma within the drying chamber includes impacting the drying chamber to allow for the movement of the dried plasma into a desired compartment.

19 ) The method of claim 17 , wherein the impacting step occurs two or more times, the sealing step occurs two or more times, the separating step occurs two or more times, or a combination thereof.

20 ) A method for converting a spray drying disposable into a dried plasma unit having the dried plasma, the spray drying disposable having a spray drying head, a drying chamber, and dried plasma, wherein the method uses a spray drying finishing apparatus that comprises an impactor, a sealer, and a separator; wherein the method comprises the steps of:
A) moving the dried plasma within the drying chamber into a first desired compartment located at a bottom portion of the spray drying disposable; B) sealing at a first location of the drying chamber to thereby create a sealed spray drying disposable having dried plasma; C) separating the sealed spray drying disposable at or near the first location to thereby create a modified spray drying disposable; D) rotating the modified spray drying disposable to thereby obtain a rotated modified spray drying disposable; E) moving the dried plasma within the drying chamber into a second desired compartment located at a portion of the spray drying disposable to form the plasma unit; F) sealing rotated modified spray drying disposable at a second location to thereby create a dried plasma unit within the rotated modified spay drying disposable; G) separating the dried plasma unit from the rotated modified spay drying disposable at or near the second location to thereby create a dried plasma unit from the spray drying disposable.

Assignees

• Velico Medical Inc

Inventors

• Erickson Kyle D
• Merritt William J

Classifications

• F26B21/50

  Ducting arrangements from the source of air or other gases to the materials or objects being dried · CPC title

• F26B21/35

  Temperature; Pressure · CPC title

• F26B21/37

  Velocity of flow; Quantity of flow · CPC title

• F26B21/331

  by using sorbent or hygroscopic materials, e.g. chemical substances or molecular sieves · CPC title

• F26B3/12 Primary

  in the form of a spray {, i.e. sprayed or dispersed emulsions or suspensions (spray drying of solutions B01D1/18)} · CPC title