Leave-on oral care compositions

Patent metadata

Field	Value
Publication number	US-2024099957-A1
Application number	US-202318530533-A
Country	US
Kind code	A1
Filing date	Dec 6, 2023
Priority date	Jun 14, 2019
Publication date	Mar 28, 2024
Grant date	—

Abstract

Leave-on oral care compositions having good spreadability and improved retention property are provided for promoting Gum Health of a user. Leave-on oral care compositions can comprise a hyaluronic acid or a salt thereof, a polyacrylic acid as a mucoadhesive polymer, and an additional polymer.

First claim

What is claimed is:

1 . A leave-on oral care composition comprising:
a) from about 0.1% to about 10%, by weight of the composition, of a hyaluronic acid or a salt thereof, wherein the hyaluronic acid has a weight average molecular weight of from about 900,000 Daltons to about 2,000,000 Daltons; b) from about 0.5% to about 10%, by weight of the composition, of a polyacrylic acid; c) from about 0.5% to about 10%, by weight of the composition, of an additional polymer, wherein the additional polymer does not include an anionic cellulose; and d) from about 30% to about 75%, by weight of the composition, of total water content.

2 . The leave-on oral care composition of claim 1 , wherein the hyaluronic acid is present in an amount of from about 0.1% to about 5%, by weight of the composition.

3 . The leave-on oral care composition of claim 1 , wherein the polyacrylic acid is present in the amount of from about 0.5% to about 5%, by weight of the composition.

4 . The leave-on oral care composition of claim 1 , further comprising from about 0.01% to about 5%, by weight of the composition, of allantoin.

5 . The leave-on oral care composition of claim 1 , wherein the additional polymer is selected from the group consisting of natural gum, linear sulfated polysaccharide, nonionic cellulose derivative, co-polymers of maleic anhydride with methyl vinyl ether, polyvinyl pyrrolidine, and combinations thereof.

6 . The leave-on oral care composition of claim 5 , wherein the additional polymer is present in the amount of from about 0.2% to about 10%, by weight of the composition.

7 . The leave-on oral care composition of claim 5 , wherein the additional polymer is selected from the group consisting of xanthan gum, carrageenan, hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxymethyl cellulose, co-polymers of maleic anhydride with methyl vinyl ether having a weight average molecular weight of about 30,000 Daltons to about 1,000,000 Daltons, polyvinyl pyrrolidine, and combinations thereof.

8 . The leave-on oral care composition of claim 1 , further comprising a polyol selected from the group consisting of glycerol, erythritol, xylitol, sorbitol, mannitol, and combinations thereof.

9 . The leave-on oral care composition of claim 8 , wherein the polyol is present in the amount of from about 1% to about 30%, by weight of the composition.

10 . The leave-on oral care composition of claim 1 , further comprising a vitamin selected from the group consisting of Vitamin C, Vitamin E, Vitamin B5, and combinations thereof.

11 . The leave-on oral care composition of claim 1 , wherein the total water content is from about 40% to about 75%, by weight of the composition.

12 . The leave-on oral care composition of claim 1 , wherein the oral care composition is in a gel form.

13 . The leave-on oral care composition of claim 1 , wherein the oral care composition is substantially free of abrasives.

14 . A method of improving Gum Health of a subject, the method comprising the steps of applying the leave-on oral care composition of claim 1 onto intraoral tissue of the subject, and leaving the oral care composition on the intraoral tissue a duration of time of from about 1 minute to about 1000 minutes.

15 . The method of claim 14 , wherein the applying step is conducted as the last step of an oral hygiene regimen.

16 . The method of claim 14 , wherein the leave-on oral care composition is applied onto the intraoral tissue of the subject with an applicator comprising a handle and a head to spread the oral care composition onto the intraoral tissue of the subject.

17 . A method of improving Gum Health of a subject, the method comprising the steps of:
(a) brushing teeth of the subject with an antibacterial toothpaste; and (b) subsequently, applying the leave-on oral care composition of claim 1 onto intraoral tissue of the subject, and leaving the oral care composition on the intraoral tissue for a duration of time of from about 1 minute to about 1000 minutes.

18 . The method of claim 17 , wherein the oral care composition is applied onto the intraoral tissue of the subject with an applicator comprising a handle and a head to spread the oral care composition onto the intraoral tissue of the subject.

19 . A kit comprising a toothpaste and the leave-on oral care composition of claim 1 .

20 . A kit comprising the leave-on oral care composition of claim 1 and a delivery carrier, wherein the delivery carrier comprises strip, film of material, dental tray, aligner, sponge material, applicator, or mixtures thereof.

Assignees

• Procter & Gamble

Inventors

• Strand Ross
• Su Yang
• Shi Yunming
• Shanmugam Thanigaivel
• Wang Guannan
• Li Xiaoxiao

Classifications

• A61K8/735 Primary

  Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof · CPC title

• A61K8/042

  Gels · CPC title

• A61K8/4946

  Imidazoles or their condensed derivatives, e.g. benzimidazoles · CPC title

• A61K8/8147

  Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers · CPC title

• A61Q11/00 Primary

  Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses · CPC title