Antiviral formulation, antiviral filtering material, methods of preparation thereof and antiviral face mask

Patent metadata

Field	Value
Publication number	US-2024081441-A1
Application number	US-202118269626-A
Country	US
Kind code	A1
Filing date	Dec 17, 2021
Priority date	Dec 30, 2020
Publication date	Mar 14, 2024
Grant date	—

Abstract

A first subject of the present invention has an antiviral formulation with metallic copper particles in an unoxidized form and having a median particle diameter inferior or equal to 200 nm, graphene oxide or reduced graphene oxide, and a bonding matrix material. A second subject of the invention has an antiviral filtering material with a layer of textile and at least one layer of an antiviral coating comprising metallic copper particles in an unoxidized form and having a median particle diameter inferior or equal to 200 nm, graphene oxide or reduced graphene oxide, and a bonding matrix into which both metallic copper particles and graphene oxide or reduced graphene oxide are anchored. The invention also concerns methods of preparation of the antiviral formulation and of the antiviral filtering material. Finally, the invention includes an antiviral face mask with a layer of textile coated with the antiviral formulation.

First claim

What is claimed is:

1 - 28 . (canceled)

29 : Antiviral formulation comprising:
metallic copper particles in an unoxidized form and having a median particle diameter inferior or equal to 200 nm; graphene oxide or reduced graphene oxide; and a bonding matrix material.

30 : The antiviral formulation as recited in claim 29 wherein the metallic copper particles and the graphene oxide or the reduced graphene oxide are chemically bonded.

31 : The antiviral formulation as recited in claim 29 wherein the bonding matrix material includes a water-based resin.

32 : The antiviral formulation as recited in claim 31 wherein the water-based resin is a polyurethane resin, an acrylic resin, a polyester resin, oligomers or mixtures thereof.

33 : The antiviral formulation as recited in claim 32 wherein the water-based resin is polyurethane resin or acrylic resin, wherein the ratio between graphene oxide or reduced graphene oxide, and metallic copper particles is between 62:1 to 1:1, and wherein the ratio between graphene oxide or reduced graphene oxide and copper suspension, and the resin is between 1:1 and 600:1.

34 : The antiviral formulation as recited in claim 32 wherein further comprising a functionalized nanosilica component.

35 : The antiviral formulation as recited in claim 29 wherein the bonding matrix material includes an alkaline hydrolyzed epoxy silane.

36 : The antiviral formulation as recited in claim 35 wherein the copper particles are encapsulated.

37 : Antiviral filtering material comprising:
a layer of textile; and at least one layer of an antiviral coating including: metallic copper particles in an unoxidized form and having a median particle diameter inferior or equal to 200 nm; graphene oxide or reduced graphene oxide; and a bonding matrix, both the metallic copper particles and the graphene oxide or reduced graphene oxide being anchored in the boding matrix.

38 : The antiviral filtering material as recited in claim 37 wherein the bonding matrix further includes a functionalized nanosilica component.

39 : The antiviral filtering material as recited in claim 37 wherein the bonding matrix includes a water-based resin.

40 : The antiviral filtering material as recited in claim 39 wherein the water-based resin is a polyurethane resin, an acrylic resin, a polyester resin, oligomers or mixtures thereof.

41 : The antiviral filtering material as recited in claim 40 wherein the water-based resin is polyurethane resin or acrylic resin, wherein the ratio between graphene oxide or reduced graphene oxide, and metallic copper particles is between 62:1 to 1:1, and wherein the ratio between graphene oxide or reduced graphene oxide and copper suspension and the resin is between 1:1 and 1500:1.

42 : The antiviral filtering material as recited in claim 40 wherein the bonding matrix includes a functionalized nanosilica network into which both graphene oxide and metallic copper particles are chemically bonded.

43 : The antiviral filtering material as recited in claim 37 wherein the textile includes natural fibers, synthetic fibers or a mixture thereof.

44 : A method of preparation of an antiviral formulation, the method comprising at least the following steps:
preparing in alkaline conditions an aqueous dispersion of metallic copper particles having a median particle diameter inferior or equal to 200 nm and stabilized graphene oxide or stabilized reduced graphene oxide; and mixing said aqueous dispersion with a bonding matrix material under alkaline conditions so as to obtain an antiviral formulation comprising metallic copper particles in an unoxidized form, graphene oxide or reduced graphene oxide and a bonding matrix material.

45 : The method as recited in claim 44 wherein the preparation of the aqueous dispersion of metallic copper particles and graphene oxide or reduced graphene oxide includes the following steps:
stabilizing graphene oxide or reduced graphene oxide by mixing with a solvent, for example water, and a dispersing additive
adding metallic copper particles in the solution and high shear mixing the resulting preparation,
centrifugating the resulting preparation, and
collecting the supernatant so as to obtain the aqueous dispersion of metallic copper particles and stabilized graphene oxide or stabilized reduced graphene oxide,
wherein all these operations are conducted under alkaline conditions.

46 : The method as recited in claim 44 wherein the bonding matrix material includes polyurethane resin, acrylic resin, polyester resin, oligomers or a mixture thereof.

47 : The method as recited in claim 44 further comprising adding an aqueous dispersion of functionalized nanosilica after mixing the aqueous dispersion with the bonding matrix material.

48 : A method of preparation of an antiviral formulation, the method comprising at least the following steps:
encapsulating metallic copper particles having a median particle diameter inferior or equal to 200 nm, adding the epoxy silane to the encapsulated metallic copper particles, hydrolyzing the epoxy silane under sol-gel process conditions, adding graphene oxide or reduced graphene oxide under sol-gel process conditions, wherein all the steps are operated under alkaline conditions, so as to obtain an antiviral formulation including metallic copper particles in an unoxidized form, graphene oxide or reduced graphene oxide, and a bonding matrix material.

49 : The method as recited in claim 48 wherein the epoxy silane is 3-glycidoxypropyltrimethoxysilane.

50 : The method as recited in claim 48 wherein the encapsulation of the copper particles is operated with glycerin, polyvinyl acetate, or lignin.

51 : The method as recited in claim 48 further comprising adding a water-based resin after adding graphene oxide or reduced graphene oxide.

52 : A method of preparation of an antiviral filtering material, the method comprising at least the following steps:
preparing an antiviral formulation according to the method as recited in claim 44 ; supplying a textile and coating said textile with said antiviral formulation, and curing the coated textile so as to obtain an antiviral filtering material.

53 : The method as recited in claim 52 wherein the step of coating the textile with the antiviral formulation is a dip coating, screen printing, spray coating or roller coating.

54 : The method as recited in claim 52 wherein the curing of the coated textile is operated at a temperature comprised between 70 and 230° C. during 1 to 13 minutes.

55 : An antiviral face mask made from an antiviral filtering material comprising a layer of textile coated with an antiviral formulation comprising metallic copper particles in an unoxidized form and having a median particle diameter inferior or equal to 200 nm, and graphene oxide or reduced graphene oxide, and a bonding matrix into which both metallic copper particles and graphene oxide or reduced graphene oxide are anchored.

56 : The antiviral face mask as recited in claim 55 wherein the antiviral formulation further comprises a functionalized nanosilica component.

Assignees

• Arcelormittal

Inventors

• Alvarez-Alvarez Abel
• Manjon Fernandez Alvaro
• Sanz Moral Luis Miguel
• NORIEGA PEREZ David
• Rodríguez García Jorge
• Megido Fernandez Laura
• Bohm Sivasambu
• Suarez Sanchez Roberto
• Perez Rodriguez Marcos

Classifications

• A41D13/1192 Primary

  with antimicrobial agent · CPC title

• A01N25/10

  Macromolecular compounds · CPC title

• A01N25/28

  Microcapsules {or nanocapsules} · CPC title

• A01N59/20

  Copper · CPC title

• A01P1/00

  Disinfectants; Antimicrobial compounds or mixtures thereof · CPC title