Accurate diaphragm thickness and function evaluation using ultrasound and mechanical ventilator signals

Patent metadata

Field	Value
Publication number	US-2023419527-A1
Application number	US-202318213286-A
Country	US
Kind code	A1
Filing date	Jun 23, 2023
Priority date	Jun 23, 2022
Publication date	Dec 28, 2023
Grant date	—

Abstract

A diaphragm measurement device ( 1 ) includes at least one electronic processor ( 13 ) programmed to perform a diaphragm measurement method ( 100 ) including receiving ultrasound imaging data of a dimension of a diaphragm of a patient during inspiration and expiration while the patient undergoes mechanical ventilation therapy with a mechanical ventilator ( 2 ); receiving respiratory data of the patient during inspiration and expiration while the patient undergoes the mechanical ventilation therapy; calculating a diaphragm thickness metric based on the received ultrasound imaging data of the diaphragm of the patient and the received respiratory data; and displaying, on a display device ( 14 ), a representation ( 30 ) of the calculated diaphragm thickness metric.

First claim

1 . A diaphragm measurement device ( 1 ), comprising:
at least one electronic processor ( 13 ) programmed to perform a diaphragm measurement method ( 100 ) including: receiving ultrasound imaging data of a dimension of a diaphragm of a patient during inspiration and expiration while the patient undergoes mechanical ventilation therapy with a mechanical ventilator ( 2 ); receiving respiratory data of the patient during inspiration and expiration while the patient undergoes the mechanical ventilation therapy; calculating a diaphragm thickness metric based on the received ultrasound imaging data of the diaphragm of the patient and the received respiratory data; and displaying, on a display device ( 14 ), a representation ( 30 ) of the calculated diaphragm thickness metric.

2 . The device ( 1 ) of claim 1 , wherein the diaphragm thickness metric includes a diaphragm thickening ratio indicative of a diaphragm thickness during inspiration relative to a diaphragm thickness during expiration.

3 . The device ( 1 ) of either one of claims 1 and 2 , wherein the diaphragm thickness metric includes a mean diaphragm thickness over multiple respiratory cycles.

4 . The device ( 1 ) of any one of claims 1 - 3 , further comprising:
an ultrasound imaging device ( 18 ) including an ultrasound patch ( 20 ) attached to a portion of the patient, wherein the at least one electronic processor ( 13 ) controls the ultrasound imaging device to receive the ultrasound imaging data of the diaphragm of the patient from the ultrasound patch.

5 . The device ( 1 ) of any one of claims 1 - 4 , wherein the respiratory data of the patient comprises one of an airway pressure or airway flow in an airway of the patient, and the at least one electronic processor ( 13 ) is further programmed to calculate the diaphragm thickness metric based on the airway pressure or the airway flow.

6 . The device ( 1 ) of claim 5 , wherein the respiratory data comprises a mean airway pressure or airway flow value at an end of inspiration and at an end of expiration.

7 . The device ( 1 ) of claim 5 , wherein the respiratory data comprises a maximum airway pressure or airway flow value and a minimum airway pressure or airway flow value at an end of inspiration and at an end of expiration.

8 . The device ( 1 ) of any one of claims 1 - 7 , wherein the at least one electronic processor ( 13 ) is further programmed to calculate the diaphragm thickness metric as a ratio of a diaphragmatic thickness of the diaphragm and an airway pressure in an airway of the patient.

9 . The device ( 1 ) of any one of claims 1 - 7 , wherein the at least one electronic processor ( 13 ) is further programmed to calculate the diaphragm thickness metric as a ratio of a diaphragmatic thickness of the diaphragm and an airway flow in an airway of the patient.

10 . The device ( 1 ) of claim 9 , wherein the at least one electronic processor ( 13 ) is further programmed to:
calculate a responsiveness index of a patient as a ratio of a change in a compliance of the airway of the patient to a change in one or more mechanical ventilation settings of an associated mechanical ventilator ( 2 ).

11 . The device ( 1 ) of claim 10 , wherein the at least one electronic processor ( 13 ) is further programmed to:
control an associated mechanical ventilator ( 2 ) to adjust one or more parameters of the mechanical ventilation therapy delivered to the patient based on the calculated responsiveness index.

12 . The device ( 1 ) of claim 11 , wherein the at least one electronic processor ( 13 ) is further programmed to:
display, on the display device ( 14 ), a representation ( 30 ) of the calculated responsiveness index.

13 . The device ( 1 ) of any one of claims 1 - 12 , wherein the at least one electronic controller ( 13 ) is configured to:
control an associated mechanical ventilator ( 2 ) to adjust one or more parameters of the mechanical ventilation therapy delivered to the patient based on the calculated diaphragm thickness metric.

14 . The device ( 1 ) of any one of claims 1 - 13 , further comprising:
a mechanical ventilator ( 2 ) configured to deliver mechanical ventilation therapy to the patient.

15 . A diaphragm measurement method ( 100 ) comprising, with at least one electronic controller ( 13 ):
receiving ultrasound imaging data of a dimension of a diaphragm of a patient during inspiration and expiration while the patient undergoes mechanical ventilation therapy with a mechanical ventilator ( 2 ); receiving respiratory data of the patient during inspiration and expiration while the patient undergoes the mechanical ventilation therapy; calculating a diaphragm thickness metric based on the received ultrasound imaging data of the diaphragm of the patient and the received respiratory data; and displaying, on a display device ( 14 ), a representation ( 30 ) of the calculated diaphragm thickness metric.

Assignees

• Koninklijke Philips Nv

Inventors

• Hendriks Cornelis Petrus
• Buizza Roberto
• Polkey Michael
• Haartsen Jaap Roger
• Sabczynski Joerg
• Wlemker Rafael
• Koehler Thomas

Classifications

• A61B5/085

  Measuring impedance of respiratory organs or lung elasticity · CPC title

• G06T7/60 Primary

  Analysis of geometric attributes · CPC title

• G06T7/0012

  Biomedical image inspection · CPC title

• A61B8/08

  Clinical applications (A61B8/02, A61B8/04, A61B8/06 take precedence) · CPC title

• A61M16/0003

  Accessories therefor, e.g. sensors, vibrators, negative pressure · CPC title