Methods for controlled heart valve delivery

Patent metadata

Field	Value
Publication number	US-2023414350-A1
Application number	US-202318464234-A
Country	US
Kind code	A1
Filing date	Sep 10, 2023
Priority date	Nov 23, 2015
Publication date	Dec 28, 2023
Grant date	—

Abstract

A prosthetic implant delivery assembly includes a prosthetic implant and a catheter. The prosthetic implant includes a plurality of apices with apertures. Each apex of the plurality of apices is circumferentially-spaced apart relative to an adjacent apex. The catheter includes a plurality of arms and a plurality of locking elements. Each of the arms includes an opening configured to receive a respective apex of the prosthetic implant. Each of the locking elements is configured to extend through the aperture of a respective apex of the prosthetic implant. A length of at least one of the locking elements is different than a length of another locking element such that when the prosthetic implant is coupled to the catheter by the locking elements, a longitudinal axis of the prosthetic implant can be held at a tilted position relative to a longitudinal axis of the catheter.

First claim

What is claimed is:

1 . A prosthetic implant delivery assembly comprising:
a prosthetic implant comprising a plurality of apices with apertures formed therein, wherein each apex of the plurality of apices is circumferentially-spaced apart relative to an adjacent apex; and an elongate catheter comprising a plurality of arms and a plurality of locking elements, wherein each of the arms comprises an opening configured to receive a respective apex of the prosthetic implant, wherein each of the locking elements is configured to extend through the aperture of a respective apex of the prosthetic implant, and wherein a length of at least one of the locking elements is different than a length of another locking element such that when the prosthetic implant is coupled to the catheter by the locking elements, a longitudinal axis of the prosthetic implant can be held at a tilted position relative to a longitudinal axis of the catheter.

2 . The delivery assembly of claim 1 , wherein:
each of the locking elements is axially movable relative to a respective arm between a first position and a second position; in the first position, each of the locking elements extends through the aperture of a respective apex of the prosthetic implant, thereby releasably coupling the prosthetic implant to a respective arm of the catheter when the respective apex of the prosthetic implant is inserted through a respective aperture of the arm; and in the second position, each locking element is retracted from the aperture of the respective apex of the prosthetic implant, thereby releasing the respective apex of the prosthetic implant from the respective arm.

3 . The delivery assembly of claim 2 , wherein all of the locking elements move together from the first position to the second position.

4 . The delivery assembly of claim 2 , wherein at least one of the openings of the arms has a different length than another opening of the arms.

5 . The delivery assembly of claim 1 , wherein at least one of the locking elements is axially moveable relative to another locking element.

6 . The delivery assembly of claim 1 , wherein a length of at least one of the locking elements is different than a length of another locking element, and a length of each of the arms of the catheter is the same length as the other arms such that when the locking elements are retracted relative to the catheter, the at least one of the locking elements releases the prosthetic implant from the catheter and the another locking element retains the prosthetic implant to the catheter, and wherein partially releasing the prosthetic implant from the catheter allows the prosthetic implant to tilt further relative to the longitudinal axis of the catheter than when the prosthetic implant is coupled to the catheter with all of the locking elements.

7 . The delivery assembly of claim 1 , wherein the catheter further comprises a plurality of sleeves, and each sleeve is configured to be axially slidable relative to the opening of a respective arm such that the sleeves can be used to alter an effective size of the openings of the arms, wherein the effective size of each opening is a portion of the opening that is unobstructed by a respective sleeve.

8 . The delivery assembly of claim 1 , wherein at least one arm of the catheter is axially moveable relative to another arm.

9 . The delivery assembly of claim 1 , wherein a length of at least one of the locking elements is different than a length of another locking element, and a length of at least one arm of the catheter is different than a length of another arm.

10 . The delivery assembly of claim 1 , wherein the delivery assembly is configured for implanting the prosthetic implant to a native aortic valve via a retrograde approach.

11 . The delivery assembly of claim 1 , wherein in the tilted position, the longitudinal axis of the prosthetic implant can tilt up to 60 degrees relative to the longitudinal axis of the catheter.

12 . The delivery assembly of claim 1 , wherein in the tilted position, the longitudinal axis of the prosthetic implant can tilt from 0 degrees to 45 degrees relative to the longitudinal axis of the catheter.

13 . A prosthetic implant delivery assembly comprising:
a prosthetic implant comprising a plurality of apices circumferentially spaced around a first end portion of the prosthetic implant, wherein at least some of the apices comprise an aperture; and an elongate catheter comprising:
a plurality of radially expandable arms extending axially from a distal end of a shaft of the catheter, each arm having a hook portion which extends radially inwardly and configured to releasably engage a respective aperture of the prosthetic implant;
a shaft disposed radially within and movable relative to the catheter; and
an expansion element disposed on a distal end portion of the shaft and radially inwardly relative to the arms of the catheter, wherein the expansion element is movable relative to the arms of the catheter to disengage the hook portions of the arms from the prosthetic implant.

14 . The delivery assembly of claim 13 , wherein the hook portions of the arms extend radially inwardly and are angled proximally.

15 . The delivery assembly of claim 13 , wherein the expansion element has a frusto-conical shape.

16 . The delivery assembly of claim 13 , wherein the catheter is configured such that relative rotational motion between the shaft and the expansion element causes relative axial motion between the expansion element and the arms.

17 . The delivery assembly of claim 16 , wherein the expansion element comprises one or more longitudinally-extending slots, wherein the slots are configured for receiving the arms, allowing relative axial motion between the expansion element and the arms, and preventing relative rotational motion between the expansion element and the arms.

18 . The delivery assembly of claim 13 , wherein the catheter is configured such that relative axial motion between the shaft and the arms causes relative axial motion between the expansion element and the arms.

19 . The delivery assembly of claim 13 , wherein:
the expansion element is movable relative to the arms between a first position and a second position; in the first position, the expansion element is disposed distally relative to the second position and is spaced radially inwardly from the arms; and in the second position, the expansion element contacts the arms and forces the arms radially outwardly.

20 . A prosthetic implant delivery assembly comprising:
a prosthetic implant comprising a longitudinal axis extending from a first end portion to a second end portion, wherein the first end portion comprises a plurality of apices which are circumferentially-spaced apart relative to each other, and wherein at least some of the apices comprise an aperture; and an elongate catheter having a longitudinal axis extending from a proximal end portion of the catheter to a distal end portion of the catheter and a plurality of arms extending axially from the distal end of the catheter, wherein each of the arms of the catheter comprises an opening at a distal end of the arm configured to receive a respective apex of the prosthetic implant, and wherein at least one of the openings of the arms has a different length than another opening of the arms, wherein the first end portion of the prosthetic implant is releasably and pivotably coupled to the arms of the catheter such that the prosthetic implant can pivot about the arms so th

Assignees

• Edwards Lifesciences Corp

Inventors

• Desrosiers John J
• White Amanda Kristine Anderson
• Bialas Michael R
• Madrid Gilbert
• Popp Michael J
• Nguyen Thanh V
• Liu Jun
• Metchik Asher L
• Patel Darshin S

Classifications

• A61F2/243 Primary

  Deployment by mechanical expansion · CPC title

• A61F2/2436 Primary

  Deployment by retracting a sheath · CPC title

• A61F2/2418

  Scaffolds therefor, e.g. support stents · CPC title

• A61F2220/0033

  made by longitudinally pushing a protrusion into a complementary-shaped recess, e.g. held by friction fit · CPC title

• A61F2220/0008

  Fixation appliances for connecting prostheses to the body · CPC title