Method for purification of 225AC from irradiated 226RA-targets
US-9790573-B2 · Oct 17, 2017 · US
US2023402199A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2023402199-A1 |
| Application number | US-202318238972-A |
| Country | US |
| Kind code | A1 |
| Filing date | Aug 28, 2023 |
| Priority date | Sep 3, 2020 |
| Publication date | Dec 14, 2023 |
| Grant date | — |
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Compositions comprising high levels of high specific activity copper-64, and process for preparing said compositions. The compositions comprise from about 2 Ci to about 15 Ci of copper-64 and have specific activities up to about 3800 mCi copper-64 per microgram of copper. The processes for preparing said compositions comprise bombarding a nickel-64 target with a low energy, high current proton beam, and purifying the copper-64 from other metals by a process comprising ion exchange chromatography or a process comprising a combination of extraction chromatography and ion exchange chromatography.
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What is claimed is: 1 . A composition for use as a radioactive precursor comprising from 2 Ci to 15 Ci of copper-64 ( 64 Cu), wherein the radionuclidic purity of the 64 Cu is greater than 98.5%. 2 . The composition of claim 1 , wherein the radionuclidic purity of the 64 Cu is greater than 99%. 3 . The composition of claim 1 , wherein the radionuclidic purity of the 64 Cu is greater than 99.5%. 4 . The composition of claim 1 , wherein the radionuclidic purity of the 64 Cu is greater than 99.9%.
Recovery of specific isotopes from irradiated targets · CPC title
by bombardment with electrically charged particles (irradiation devices G21K5/00) · CPC title
chelates from cyclic ligands, e.g. DOTA · CPC title
specially adapted for medical application (radiation therapy using radioactive sources A61N5/10) · CPC title
Preparation involving a liquid-liquid extraction, an adsorption or an ion-exchange · CPC title
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