Dose delivery mechanism and method for providing a dose delivery mechanism

Patent metadata

Field	Value
Publication number	US-2023398307-A1
Application number	US-202217837951-A
Country	US
Kind code	A1
Filing date	Jun 10, 2022
Priority date	Jun 10, 2022
Publication date	Dec 14, 2023
Grant date	—

Abstract

A dose delivery mechanism includes a housing, a piston rod that acts on a plunger sealing a fluid compartment and moves in an axial direction relative to the housing to deliver a set dose, and a dose setting member that is movable relative to the housing during dose setting. A position of the dose setting member relative to the housing defines the set dose, and in an as-delivered condition the dose setting member is preset to a position that corresponds to a set dose higher than zero.

First claim

1 . A dose delivery mechanism comprising:
a housing; a piston rod configured to act on a plunger sealing a fluid compartment and to move in an axial direction relative to the housing to deliver a set dose; and a dose setting member movable relative to the housing during dose setting; a position of the dose setting member relative to the housing defining the set dose, and in an as-delivered condition the dose setting member being preset to a position that corresponds to a set dose higher than zero.

2 . The dose delivery mechanism according to claim 1 , wherein in the as-delivered condition the position of the dose setting member corresponds to a dose between a zero-dose and a minimum dose deliverable by the dose delivery mechanism.

3 . The dose delivery mechanism according to claim 1 , further comprising a dose indication member configured to indicate a set dose depending on a position of the dose indication member relative to the housing.

4 . The dose delivery mechanism according to claim 3 , wherein the dose setting member is the dose indication member.

5 . The dose delivery mechanism according to claim 3 , wherein in the as-delivered condition the dose indication member indicates the set dose to be different from a zero-dose.

6 . The dose delivery mechanism according to claim 1 , wherein the dose setting member is configured to move relative to the housing to set a dose that differs from a preset dose.

7 . The dose delivery mechanism according to claim 6 , wherein the dose setting member is not directly movable from the position that is preset to a zero-dose position.

8 . The dose delivery mechanism according to claim 1 , further comprising an activation member configured to be moved to initiate delivery of the set dose, and
the activation member is blocked from initiating delivery of the set dose when the dose setting member is in the position that is preset.

9 . The dose delivery mechanism according to claim 8 , wherein a separate element prevents premature moving of the activation member relative to the housing before the separate element is removed.

10 . The dose delivery mechanism according to claim 8 , wherein two parts arranged inside the housing of the dose delivery mechanism are configured to cooperate with each other to prevent unintended movement of the activation member relative to the housing starting from the position that is preset.

11 . The dose delivery mechanism according to claim 10 , wherein a first part of the two parts forms a blocking structure and a second part of the two parts forms an engagement feature configured to engage the blocking structure when the two parts are moved relative to each other in order to block the activation member from initiating delivery of the set dose when the dose setting member is in the position that is preset.

12 . The dose delivery mechanism according to claim 10 , wherein two parts arranged inside the housing of the dose delivery mechanism comprise respective dose definition elements that are configured to cooperate with each other to define multiple relative positions to each other corresponding to settable doses.

13 . The dose delivery mechanism according to claim 12 , wherein the multiple relative positions are defined by dose stops formed on a first part of the two parts which are configured to contact with a snap element on a second part of the two parts.

14 . A medicament delivery device, comprising:
a dose delivery mechanism according to claim 1 .

15 . A method for providing a dose delivery mechanism having a housing, a piston rod configured to act on a plunger sealing a fluid compartment and to move in an axial direction relative to the housing to deliver a set dose, and a dose setting member that is movable relative to the housing during dose setting, a position of the dose setting member relative to the housing defining the set dose, the method comprising:
delivering the dose delivery mechanism to a costumer in a state preset to a dose higher than zero.

16 . The dose delivery mechanism according to claim 1 , wherein in the as-delivered condition the position of the dose setting member corresponds to a dose between a zero-dose and a minimum dose for which therapy the dose delivery mechanism is intended.

17 . The dose delivery mechanism according to claim 1 , further comprising a dose indication member configured to indicate a set dose depending on a rotational or axial position of the dose indication member relative to the housing.

18 . The dose delivery mechanism according to claim 1 , wherein the dose setting member is configured to rotate relative to the housing to set a dose for therapy that differs from a preset dose.

19 . The dose delivery mechanism according to claim 8 , wherein a clip prevents premature moving of the activation member relative to the housing before the separate element is removed.

20 . The dose delivery mechanism according to claim 10 , wherein a first part of the two parts forms a circumferentially extending rib and a second part of the two parts forms an engagement feature configured to engage the blocking structure when the two parts are moved relative to each other in order to block the activation member from initiating delivery of the set dose when the dose setting member is in the position that is preset.

Assignees

• Medmix Switzerland Ag

Inventors

• Bechtold Herbert
• Costello Peter Calvin
• Focht Kenneth Allen
• Smith Daniel P

Classifications

• A61M5/31578 Primary

  based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod · CPC title

• A61M5/31568 Primary

  Means keeping track of the total dose administered, e.g. since the cartridge was inserted · CPC title

• A61M2005/3126

  Specific display means related to dosing · CPC title

• A61M5/3158

  performed by axially moving actuator operated by user, e.g. an injection button · CPC title

• A61M5/31553

  without axial movement of dose setting member · CPC title