Autoinjector

Patent metadata

Field	Value
Publication number	US-2023347054-A1
Application number	US-202318218884-A
Country	US
Kind code	A1
Filing date	Jul 6, 2023
Priority date	Nov 6, 2012
Publication date	Nov 2, 2023
Grant date	—

Abstract

An autoinjector includes a case configured to receive a syringe, a slidable member that is movable axially within the case to cause at least a portion of the syringe to move axially when the syringe is disposed within the case for dispensing a medicament through a needle of the syringe, a locking member configured to prevent actuation of the slidable member when the autoinjector is in a pre-dispense configuration, a sleeve coupled to a distal end of the case and surrounding at least a portion of a needle of the syringe when the syringe is disposed within the case, an elongate member extending proximally from the sleeve and configured to deflect the locking member to allow actuation of the plunger, and two drive springs coupled to the slidable member and configured to apply a biasing force that acts on the slidable member to move the slidable member distally.

First claim

1 . (canceled)

2 . An autoinjector comprising:
a case configured to receive a syringe; a slidable member that is movable axially within the case to cause at least a portion of the syringe to move axially when the syringe is disposed within the case for dispensing a medicament through a needle of the syringe; a locking member configured to prevent actuation of the slidable member when the autoinjector is in a pre-dispense configuration; a sleeve coupled to a distal end of the case and surrounding at least a portion of a needle of the syringe when the syringe is disposed within the case; an elongate member extending proximally from the sleeve and configured to deflect the locking member to allow actuation of the plunger; and two drive springs coupled to the slidable member and configured to apply a biasing force that acts on the slidable member to move the slidable member distally within the case, wherein the two drive springs are parallel to each other and are parallel to a distal direction.

3 . The autoinjector of claim 2 , wherein the sleeve is configured to allow push-actuation of the autoinjector when the sleeve is pushed against an injection site.

4 . The autoinjector of claim 2 , wherein the sleeve is slidable relative to the case between:
a retracted position in which the sleeve is contained within the case along a majority of its length, and an extended position in which the sleeve extends distally from the case by a distance greater than which it extends in the retracted position.

5 . The autoinjector of claim 4 , wherein the extended position of the sleeve corresponds to the pre-dispense configuration of the autoinjector.

6 . The autoinjector of claim 5 , wherein a distal end of the locking member has a first ramped surface, wherein a proximal end of the elongate member has a second ramped surface, and wherein the first and second ramped surfaces abut each other when the autoinjector is in the pre-dispense configuration.

7 . The autoinjector of claim 2 , wherein the elongate member is configured to deflect the locking member when the sleeve is pushed against the injection site.

8 . The autoinjector of claim 7 , wherein deflection of the locking member allows the slidable member to move in the distal direction under the biasing force of the two drive springs.

9 . The autoinjector of claim 2 , wherein a distal end of the locking member has a first ramped surface, wherein a proximal end of the elongate member has a second ramped surface, and wherein the first and second ramped surfaces abut each other when the autoinjector is in the pre-dispense configuration.

10 . The autoinjector of claim 2 , wherein at least one of the two drive springs comprises a tension spring.

11 . The autoinjector of claim 2 , wherein a distal end of the locking member has a first ramped surface, wherein a proximal end of the elongate member has a second ramped surface, and wherein the first and second ramped surfaces abut each other when the autoinjector is in the pre-dispense configuration, wherein the elongate member is configured to deflect the locking member when the sleeve is pushed against the injection site, wherein deflection of the locking member allows the slidable member to move in the distal direction under the biasing force of the two drive springs, and wherein at least one of the two drive springs comprises a tension spring.

12 . The autoinjector of claim 2 , further comprising:
a door hingedly coupled to the case and adjustable between an open position and a closed position; and a linkage that couples the door to the case.

13 . The autoinjector of claim 12 , wherein the linkage is further coupled to at least one of the two drive springs.

14 . The autoinjector of claim 12 , wherein the door is biased to the open position.

15 . The autoinjector of claim 12 , wherein the door is configured to be maintained in the closed position.

16 . The autoinjector of claim 13 , wherein the door is biased to the open position, and wherein the door is configured to be maintained in the closed position.

17 . The autoinjector of claim 2 , further comprising a collar that is configured to engage a needle boot of the syringe when the syringe is disposed within the case.

18 . The autoinjector of claim 2 , further comprising one or more user feedback mechanisms associated with an injection.

19 . The autoinjector of claim 18 , wherein the one or more user feedback mechanisms comprise a visual feedback, and wherein the one or more user feedback mechanisms comprise an audible feedback.

20 . An autoinjector comprising:
a case configured to receive a syringe; a slidable member that is movable axially within the case to cause at least a portion of the syringe to move axially when the syringe is disposed within the case for dispensing a medicament through a needle of the syringe; a locking member configured to prevent actuation of the slidable member when the autoinjector is in a pre-dispense configuration a sleeve coupled to a distal end of the case and surrounding at least a portion of a needle of the syringe when the syringe is disposed within the case; an elongate member extending proximally from the sleeve and configured to deflect the locking member to allow actuation of the plunger; two drive springs coupled to the slidable member and configured to apply a biasing force that acts on the slidable member to move the slidable member distally within the case, wherein the two drive springs are parallel to each other and are parallel to a distal direction; a door hingedly coupled to the case and adjustable between an open position and a closed position; a linkage that couples the door to the case; and a collar that is configured to engage a needle boot of the syringe when the syringe is disposed within the case, wherein the elongate member is configured to deflect the locking member when the sleeve is pushed against the injection site, wherein deflection of the locking member allows the slidable member to move in the distal direction under the biasing force of the two drive springs, wherein the locking member has a first ramped surface, wherein the elongate member has a second ramped surface, and wherein the first and second ramped surfaces abut each other when the autoinjector is in the pre-dispense configuration, and wherein at least one of the two drive springs comprises a tension spring.

21 . A system comprising:
a syringe containing a medicament; and an autoinjector comprising:
a case configured to receive the syringe;
a slidable member that is movable axially within the case to cause at least a portion of the syringe to move axially when the syringe is disposed within the case for dispensing the medicament through a needle of the syringe;
a locking member configured to prevent actuation of the slidable member when the autoinjector is in a pre-dispense configuration;
a sleeve coupled to a distal end of the case and surrounding at least a portion of a needle of the syringe when the syringe is disposed within the case;
an elongate member extending proximally from the sleeve and configured to deflect the locking member to allow actuation of the slidable member; and
two drive springs coupled to the slidable member and configured to apply a biasing force that acts on the slidable member to move the slidable member distally within the case, wherein the two drive springs are parallel to each other and are parallel to a distal direction.

22 . The s

Assignees

• Sanofi Aventis Deutschland

Inventors

• Henderson Charley
• Cross David
• Jennings Douglas Ivan
• Mcginley Ryan Anthony

Classifications

• A61M5/2033 Primary

  Spring-loaded one-shot injectors with or without automatic needle insertion (multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287) · CPC title

• A61M5/3129

  Syringe barrels (A61M5/3205 and A61M5/50 take precedence) · CPC title

• A61M5/3245

  Constructional features thereof, e.g. to improve manipulation or functioning · CPC title

• A61M5/326

  Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user · CPC title

• A61M2005/202

  cocking means, e.g. to bias the main drive spring of an injector · CPC title