Sutureless connectors and methods of preparing and using same

Patent metadata

Field	Value
Publication number	US-2023346368-A1
Application number	US-202318306351-A
Country	US
Kind code	A1
Filing date	Apr 25, 2023
Priority date	Apr 27, 2022
Publication date	Nov 2, 2023
Grant date	—

Abstract

A tissue connector may include a body formed of one or more layers of material, and at least one barbed suture attached to the body. A related method of forming a tissue connector may include forming a body from one or more layers of a material, and attaching at least one barbed suture to the body. In addition, a related method of repairing tissue using a tissue connector may include orienting the tissue connector around coapted or damaged tissue, so that the coapted or damaged tissue contacts the inner surface of the tissue connector, and twisting ends of the at least one barbed suture so that the at least one barbed suture engages the coapted or damaged tissue.

First claim

What is claimed is:

1 . A tissue connector, comprising:
a body formed of one or more layers of at least one material; and at least one barbed suture attached to the body so that at least a portion of the at least one barbed suture is exposed along a surface of the body.

2 . The tissue connector of claim 1 , wherein the body is a hollow tube, and wherein the surface is an innermost surface of the hollow tube.

3 . The tissue connector of claim 1 , wherein the body is a sheet.

4 . The tissue connector of claim 1 , wherein the at least one material is small intestinal submucosa (SIS).

5 . The tissue connector of claim 1 , wherein the at least one barbed suture is sewn through the one or more layers that form the body so that portions of the at least one barbed suture pass through all of the one or more layers.

6 . The tissue connector of claim 1 , wherein the one or more layers includes two or more layers, and wherein the at least one barbed suture is sewn within or between layers, of the two or more layers, so that portions of the at least one barbed suture are entrapped within or between the two or more layers.

7 . The tissue connector of claim 1 , wherein the body is a hollow tube, the one or more layers includes two or more layers, and the at least one barbed suture is sewn into the body with portions of the at least one barbed suture being exposed on an innermost surface of the hollow tube, and alternating portions of the at least one barbed suture being buried within the two or more layers.

8 . The tissue connector of claim 1 , wherein the one or more layers includes 1 layer to about 12 layers.

9 . The tissue connector of claim 1 , wherein the at least one barbed suture is oriented, relative to the body of the tissue connector, in one of:
a longitudinal configuration; a circumferential configuration; a net configuration; and a spiral configuration.

10 . A method of forming a tissue connector, the method comprising:
forming a body from one or more layers of at least one material; and attaching at least one barbed suture to the body so that at least a portion of the at least one barbed suture is exposed along a surface of the body.

11 . The method of claim 10 , wherein the at least one material is small intestinal submucosa (SIS).

12 . The method of claim 10 , wherein the body is a sheet.

13 . The method of claim 10 , wherein the attaching the at least one barbed suture includes:
inserting each suture, of the at least one barbed suture, through all of the one or more layers of the body, (a) from an outer surface to an inner surface near one end of the body, and (b) from the inner surface to the outer surface near another end of the body; and tying a knot at at least one of an end of each suture.

14 . The method of claim 13 , wherein the forming the body includes:
providing the one or more layers in a wet state; and allowing the one or more layers to dry, wherein the inserting of each suture is performed after the one or more layers have dried.

15 . The method of claim 10 , wherein the one or more layers includes two or more layers, and the attaching the at least one barbed suture includes:
inserting each suture, of the at least one barbed suture, (a) from an inner surface through an innermost layer, of the two or more layers of the body, at one or more locations along a length of the body, and (b) back through the innermost layer to the inner surface at alternating locations along the length of the body.

16 . The method of claim 15 , wherein attaching at least one barbed suture to the body includes inserting each suture while the innermost layer of material is in a wet state, and wherein the method further comprises:
allowing, after the inserting of each suture, the innermost layer of material to dry; and adding one or more additional layers of material on an outer surface of the dried innermost layer.

17 . The method of claim 10 , wherein the forming the body includes:
aligning layers of the material; and rolling the layers of material into a tube shape.

18 . The method of claim 10 , wherein the one or more layers includes 1 layer to about 12 layers.

19 . The method of claim 10 , wherein the at least one barbed suture is oriented, relative to the body of the tissue connector, in one of:
a longitudinal configuration; a circumferential configuration; a net configuration; and a spiral configuration.

20 . A method of repairing tissue using a tissue connector according to claim 1 , the method comprising:
orienting the tissue connector around coapted or damaged tissue, so that the coapted or damaged tissue contacts an inner surface of the tissue connector; and twisting ends of the at least one barbed suture so that the at least one barbed suture engages the coapted or damaged tissue.

Assignees

• Axogen Corp

Inventors

• Hamaker Kiri K
• Simon Alec
• Agrawal Nik
• Diluccio Robert
• Scopelianos Angelo

Classifications

• A61B2017/00526

  Methods of manufacturing · CPC title

• A61B2017/1132

  End-to-end connections · CPC title

• A61B2017/06176

  with protrusions, e.g. barbs · CPC title

• A61B17/1128

  of nerves · CPC title

• A61B17/06166 Primary

  Sutures (suture materials A61L17/00; manufacture of artificial threads D01D; treatment of threads D06M) · CPC title