Medical fluid injector

Patent metadata

Field	Value
Publication number	US-2023302220-A1
Application number	US-202318317528-A
Country	US
Kind code	A1
Filing date	May 15, 2023
Priority date	Mar 15, 2013
Publication date	Sep 28, 2023
Grant date	—

Abstract

Systems and methods for intelligently delivering fluid to a targeted tissue are described. The systems and methods may include directing a pump to distribute fluid to a targeted tissue and receiving one or more signals from an intracorporeal sensing system, where the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue. The systems and methods may also include determining whether the one or more sensed feedback parameters are within an acceptable range. If the one or more sensed feedback parameters are not within the acceptable range, the systems and methods may include determining an adjusted velocity for the plunger necessary to adjust the pressure of the fluid in the pump so that the one or more sensed feedback parameters move within the acceptable range and directing the pump to distribute the fluid at the adjusted velocity

First claim

1 . A non-transitory processor-readable storage medium comprising one or more programming instructions that, when executed by one or more processors, cause the one or more processors to:
control a pump to distribute a fluid to a targeted tissue of a patient based on a first predetermined value of a first controlled parameter in accordance with each of a first phase and a second phase of an injection protocol; receive, during each of the first phase and the second phase, one or more signals from a sensing system corresponding to a first limiting parameter, wherein the first limiting parameter comprises at least one of: a pressure at the pump, a flow rate at the pump, a pressure in a receiving vessel, a flow rate in the receiving vessel, a pressure in the targeted tissue, or a flow rate in the targeted tissue; determine, during each of the first phase and the second phase, whether the first limiting parameter is outside an acceptable range of the first limiting parameter; determine, during each of the first phase and the second phase, an adjusted value of the first controlled parameter in response to determining that the first limiting parameter is outside the acceptable range of the first limiting parameter; and control, during each of the first phase and the second phase, the pump to distribute the fluid to the targeted tissue based on the adjusted value of the first controlled parameter, wherein the acceptable range of the first limiting parameter is different during the first phase than during the second phase.

2 . The non-transitory processor-readable storage medium of claim 1 , wherein the first controlled parameter comprises at least one of an injection pressure, an injection flow rate, and an injection volume.

3 . The non-transitory processor-readable storage medium of claim 1 , wherein the acceptable range of the first limiting parameter is based on at least one of a threshold at which the targeted tissue will be damaged and a mechanical capacity of the pump.

4 . The non-transitory processor-readable storage medium of claim 1 , wherein the one or more processors are further configured to:
control the pump to deliver the fluid to the targeted tissue based on a second predetermined value of a second controlled parameter, and wherein the second controlled parameter is equal to or different than the first controlled parameter.

5 . The non-transitory processor-readable storage medium of claim 1 , wherein the one or more signals further correspond to a duration parameter, wherein the duration parameter comprises at least one of: an injection time, the pressure at the pump, the flow rate at the pump, the pressure in the receiving vessel, the pressure in the targeted tissue, a image property, a tissue stretch property, a tissue conductivity, a tissue ultrasound property, the flow rate in the targeted tissue, a fluid cell count, a fluid particle count, and a density of the measurable tracer, and
wherein the one or more processors are further configured to: determine that a target value of the duration parameter has been met; and control the pump to distribute the fluid to the targeted tissue based on a second predetermined value of a second controlled parameter in accordance with the second phase of the injection protocol.

6 . The non-transitory processor-readable storage medium of claim 5 , wherein the second controlled parameter is equal to or different than the first controlled parameter.

7 . The non-transitory processor-readable storage medium of claim 1 , wherein controlling the pump to distribute the fluid to the targeted tissue comprises controlling the pump to distribute the fluid to the targeted tissue at a pressure of about 10 psi to about 2000 psi.

8 . The non-transitory processor-readable storage medium of claim 1 , wherein the one or more processors are further configured to:
generate an alert to a user in response to determining that the first limiting parameter is outside the acceptable range; and control the pump to halt the injection protocol in response to not receiving from the user a response to the alert.

9 . The non-transitory processor-readable storage medium of claim 1 , wherein the pump is selected from a group consisting of a piston pump, a reciprocating pump, a rotational pump, a gear pump, a peristaltic pump and a diaphragm pump.

10 . The non-transitory processor-readable storage medium of claim 1 , wherein the pump is a peristaltic pump.

11 . A non-transitory processor-readable storage medium comprising one or more programming instructions that, when executed by one or more processors, cause the one or more processors to:
direct a pump to distribute a fluid into a targeted tissue of a patient at an initial velocity; receive one or more signals from an intracorporeal sensing system, wherein the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue; determine whether the one or more sensed feedback parameters are within an acceptable range; if the one or more sensed feedback parameters are not within the acceptable range, determine an adjusted velocity; and direct the pump to distribute the fluid into the targeted tissue at the adjusted velocity; thereby enabling the fluid to be delivered automatically into the targeted tissue of the patient.

12 . The non-transitory processor-readable storage medium of claim 11 , further comprising one or more programming instructions, that, when executed, direct the one or more processors to:
receive one or more inputs, wherein the one or more inputs correspond to data that defines the acceptable range.

13 . The non-transitory processor-readable storage medium of claim 11 , wherein the pump is selected from the group consisting of a piston pump, a reciprocating pump, a rotational pump, a gear pump, a peristaltic pump and a diaphragm pump.

14 . The non-transitory processor-readable storage medium of claim 11 , wherein the pump is a peristaltic pump.

15 . The non-transitory processor-readable storage medium of claim 11 , wherein the one or more sensed feedback parameters comprises intravascular pressure, an image property, a tissue stretch property, a tissue conductivity, a tissue ultrasound property, a flow rate in the targeted tissue, a fluid cell count, a fluid particle count, and a density of a measurable tracer.

16 . The non-transitory processor-readable storage medium of claim 11 , wherein the intracorporeal sensing system comprises a sensor that is disposed at or near the targeted tissue.

17 . The non-transitory processor-readable storage medium of claim 11 , further comprising:
a display in operable communication with the one or more processors; and one or more programming instructions that, when executed, direct the one or more processors to direct the display to show data corresponding to the acceptable range in a user-readable format.

18 . The non-transitory processor-readable storage medium of claim 11 , wherein the one or more signals further correspond to a duration parameter, wherein the duration parameter comprises at least one of: an injection time, the pressure at the pump, the flow rate at the pump, the pressure in a receiving vessel, the pressure in the targeted tissue, an image property, a tissue stretch property, tissue conductivity, a tissue ultrasound property, the flow rate in the targeted tissue, a fluid cell count, a fluid particle count, and a density of a measurable tracer, and
wherein the one or more processors are further configured to: determine, by one of the one or more processors,

Assignees

• Bayer Healthcare Llc

Inventors

• Uram Martin
• Yanniello Michael
• Tucker Barry
• Mishler David
• Rhinehart Edward
• Trocki Mark
• Uber Iii Arthur
• Brosovich John

Classifications

• A61M5/1723 Primary

  using feedback of body parameters, e.g. blood-sugar, pressure (measurement of body parameters A61B5/00) · CPC title

• A61M5/14566

  with a replaceable reservoir for receiving a piston rod of the pump · CPC title

• A61M5/16877

  Adjusting flow; Devices for setting a flow rate · CPC title

• A61M5/1452

  pressurised by means of pistons · CPC title

• A61M2205/3576

  with non implanted data transmission devices, e.g. using external transmitter or receiver · CPC title