What technology area does this patent fall under?

Primary CPC classification C12Q1/6883. Mapped technology areas include Chemistry & Metallurgy.

When was this patent published?

Publication date Thu Jul 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.

What related patents are in patentsdb?

We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).

Method for detecting atopic dermatitis

Patent metadata
Field	Value
Publication number	US-2023235399-A1
Application number	US-202117922565-A
Country	US
Kind code	A1
Filing date	Apr 28, 2021
Priority date	May 1, 2020
Publication date	Jul 27, 2023
Grant date	—

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Abstract

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Provided are a marker for detecting atopic dermatitis, and a method for detecting atopic dermatitis using the marker. The method for detecting atopic dermatitis in a test subject comprises a step of measuring an expression level of a gene or an expression product thereof contained in a biological sample collected from the test subject.

First claim

Opening claim text (preview).

1 . A method for detecting adult atopic dermatitis in an adult test subject, comprising a step of measuring an expression level of at least one gene selected from the group of 17 genes consisting of TMPRSS11E, MECR, RASA4CP, ARRDC4, EIF1AD, FDFT1, ZNF706, TEX2, RPS6KB2, CTBP1, ZNF335, DGKA, PPP1R9B, SPDYE7P, DNASE1L1, GNB2 and CSNK1G2 or an expression product thereof in a biological sample collected from the test subject. 2 . The method according to claim 1 , wherein the expression level of the gene or the expression product thereof is measured as an expression level of mRNA. 3 . The method according to claim 1 , wherein the gene or the expression product thereof is RNA contained in skin surface lipids of the test subject. 4 . The method according to claim 1 , wherein the presence or absence of adult atopic dermatitis is evaluated by comparing the measurement value of the expression level with a reference value of the gene or the expression product thereof. 5 . The method according to claim 1 , wherein the presence or absence of adult atopic dermatitis in the test subject is evaluated by the following steps: preparing a discriminant which discriminates between an adult atopic dermatitis patient and an adult healthy subject by using measurement values of an expression level of the gene or the expression product thereof derived from an adult atopic dermatitis patient and an expression level of the gene or the expression product thereof derived from an adult healthy subject as teacher samples; substituting the measurement value of the expression level of the gene or the expression product thereof obtained from the biological sample collected from the test subject into the discriminant; and comparing the obtained results with a reference value. 6 . The method according to claim 5 , wherein expression levels of all the genes of the group of 17 genes or expression products thereof are measured. 7 . The method according to claim 5 , wherein expression levels of the at least one gene selected from the group of 17 genes as well as at least one gene selected from the group of 245 genes shown in the following Table A-a except for the 17 genes, or expression products thereof are measured TABLE A-a ACAT1 CDS1 FABP7 HMHA1 MTSS1 PSMA5 SSH1 ACO1 CEP76 FABP9 IL17RA MVP PSMB4 ST6GALNAC2 ADAP2 CETN2 FAM108B1 IL2RB MYO6 PTPN18 TCHHL1 AKAP17A CHMP4C FAM120A ILF3 NCOR2 RAB11FIP5 TEX2 AKT1 CISD1 FAM190B ISCA1 NCS1 RABL6 TGFB1 ANXA1 COBLL1 FAM26E ITPRIPL2 NDUFA4 RAC1 THBD APOBR COPS2 FBXL17 KIAA0146 NIPSNAP3A RAI14 TM7SF2 ARHGAP23 COX6A1 FBXL18 KIAA0513 NMRK1 RASA4CP TMC5 ARHGAP24 COX7B FBXL6 KLK5 NPEPL1 RB1CC1 TMEM165 ARHGAP29 CREG1 FBXO32 KRT23 NPR1 RGS19 TMEM222 ARHGAP4 CRISPLD2 FDFT1 KRT25 NPR2 RHOC TMPRSS11E ARL8A CRTC2 FIS1 KRT71 NR1D1 RNPEPL1 TNRC18 ARRDC4 CRY2 FMN1 LCE1D NUDT16 RORC TPGS2 ATOX1 CSNK1G2 FOSB LCE2C OAT RPS6KB2 TSTD1 ATP12A CSTB FOXQ1 LENG9 OGFR RRM1 TTC39B ATP5A1 CTBP1 FURIN LEPREL1 PADI1 SAP30BP TWSG1 ATPIF1 CTDSP1 GABARAPL2 LMNA PALD1 SCARB2 TYK2 ATXN7L3B CTSB GDE1 LOC146880 PARP4 SFN U2AF2 BAX CTSL2 GIGYF1 LOC152217 PCDH1 SH3BGRL2 UNC13D BCKDHB CXCL16 GLRX LRP8 PCSK7 SHC1 UQCRQ BCRP3 CYTH2 GNA15 LY6D PCTP SIRT6 USP38 BSG DBNDD2 GNB2 LYNX1 PDZK1 SKP1 VHL C15orf23 DBT GPD1 MAN2A2 PHB SLC12A9 VOPP1 C16orf70 DGKA GPNMB MAPK3 PINK1 SLC25A16 VPS4B C17orf107 DHX32 GRASP MAPKBP1 PLAA SLC25A33 WBSCR16 C19orf71 DNASE1L1 GRN MARK2 PLEKHG2 SLC2A4RG WDR26 C1QB DOPEY2 GSDMA MAZ PLP2 SLC

Assignees

Kao Corp

Inventors

Classifications

C12Q1/6886
for cancer (immunoassay for cancer G01N33/575) · CPC title
C12Q1/686
Polymerase chain reaction [PCR] · CPC title
C12Q1/6883Primary
for diseases caused by alterations of genetic material · CPC title
C12Q2600/158
Expression markers · CPC title
G01N33/6893Primary
related to diseases not provided for elsewhere · CPC title

Patent family

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View patent family 78332005

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What does patent US2023235399A1 cover?: Provided are a marker for detecting atopic dermatitis, and a method for detecting atopic dermatitis using the marker. The method for detecting atopic dermatitis in a test subject comprises a step of measuring an expression level of a gene or an expression product thereof contained in a biological sample collected from the test subject.
Who is the assignee on this patent?: Kao Corp
What technology area does this patent fall under?: Primary CPC classification C12Q1/6883. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?: Publication date Thu Jul 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?: We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).