Electrophoresis device

Patent metadata

Field	Value
Publication number	US-2023204539-A1
Application number	US-202018008461-A
Country	US
Kind code	A1
Filing date	Jun 26, 2020
Priority date	Jun 26, 2020
Publication date	Jun 29, 2023
Grant date	—

Abstract

An electrophoresis device of the present disclosure includes: a capillary filled with a phoresis medium; a buffer container accommodating a buffer solution; a storage portion storing a sample container accommodating a sample; at least one autosampler transporting each of the sample container and the buffer container; and a control unit controlling driving of the autosampler, in which the control unit drives the autosampler such that, while the buffer container is disposed at a capillary position where one end portion of the capillary is positioned, the sample container is transported from the storage portion to a standby position near the capillary position, and, when the buffer container has been transported from the capillary position to the standby position, the sample container is transported from the standby position to the capillary position.

First claim

1 . An electrophoresis device comprising:
a capillary filled with a phoresis medium; a buffer container accommodating a buffer solution; a storage portion storing a sample container accommodating a sample; at least one autosampler transporting each of the sample container and the buffer container; and a control unit controlling driving of the autosampler, wherein the control unit drives the autosampler such that while the buffer container is disposed at a capillary position where one end portion of the capillary is positioned, the sample container is transported from the storage portion to a standby position near the capillary position, and when the buffer container has been transported from the capillary position to the standby position, the sample container is transported from the standby position to the capillary position.

2 . The electrophoresis device according to claim 1 ,
wherein the autosampler includes a sample autosampler transporting the sample container and a buffer autosampler transporting the buffer container, and the control unit drives the buffer autosampler so as to transport the buffer container between the capillary position and the standby position, and drives the sample autosampler so as to transport the sample container between the storage portion, the standby position, and the capillary position.

3 . The electrophoresis device according to claim 1 , further comprising:
a first fixing unit fixing the sample container or the buffer container at the capillary position; and a second fixing unit fixing the sample container or the buffer container at the standby position, wherein the autosampler is one in number, and the control unit drives the autosampler such that the buffer container is transported between the first fixing unit and the second fixing unit, and the sample container is transported between the storage portion, the first fixing unit, and the second fixing unit.

4 . The electrophoresis device according to claim 1 ,
wherein the control unit drives the autosampler such that the transport of the sample container is started after the capillary is filled with the phoresis medium and the sample container is withdrawn from the capillary position after the sample container is transported to the capillary position and the sample is injected into the capillary and before electrophoresis is started.

5 . The electrophoresis device according to claim 2 , wherein a drive region of the sample autosampler and a drive region of the buffer autosampler are different except for the capillary position.

6 . The electrophoresis device according to claim 1 , wherein the control unit locks the storage portion when the autosampler is not at a predetermined position and unlocks the storage portion when the autosampler is at the predetermined position.

7 . The electrophoresis device according to claim 1 , further comprising an information reading unit in the electrophoresis device,
wherein information on the sample is marked on the sample container, and the control unit drives the autosampler so as to transport the sample container from the storage portion to a reading position of the information reading unit.

8 . The electrophoresis device according to claim 7 ,
wherein the storage portion has a sensor detecting presence or absence of the sample container, and when the sensor detects that the sample container has been disposed, the control unit drives the autosampler so as to transport the sample container from the storage portion to the reading position, and reads the information on the sample based on a read signal of the information reading unit.

9 . The electrophoresis device according to claim 8 ,
wherein the storage portion stores the sample container at a plurality of storage positions, the sensor is provided at each of the plurality of storage positions, and the control unit drives the autosampler so as to transport the sample container to the reading position from the storage position where the sensor has detected that the sample container has been disposed.

10 . The electrophoresis device according to claim 2 , wherein the control unit simultaneously drives the sample autosampler and the buffer autosampler at a predetermined timing.

11 . An electrophoresis device comprising:
a capillary filled with a phoresis medium; a storage portion storing a sample container accommodating a sample; an autosampler transporting the sample container; an information reading unit reading information on the sample marked on the sample container; and a control unit controlling driving of the autosampler, wherein the control unit drives the autosampler so as to transport the sample container from the storage portion to a reading position of the information reading unit.

12 . The electrophoresis device according to claim 11 ,
wherein the storage portion has a sensor detecting presence or absence of the sample container, and when the sensor detects that the sample container has been disposed, the control unit drives the autosampler so as to transport the sample container from the storage portion to the reading position, and reads the information on the sample based on a read signal of the information reading unit.

13 . The electrophoresis device according to claim 12 ,
wherein the storage portion stores the sample container at a plurality of storage positions, the sensor is provided at each of the plurality of storage positions, and the control unit drives the autosampler so as to transport the sample container to the reading position from the storage position where the sensor has detected that the sample container has been disposed.

14 . The electrophoresis device according to claim 11 , further comprising a buffer autosampler transporting a buffer container accommodating a buffer.

15 . The electrophoresis device according to claim 11 , further comprising:
a buffer container accommodating a buffer; a first fixing unit fixing the sample container or the buffer container at a capillary position where one end portion of the capillary is positioned; and a second fixing unit fixing the sample container or the buffer container at a standby position near the capillary position, wherein the control unit drives the autosampler such that the buffer container is transported between the first fixing unit and the second fixing unit, and the sample container is transported between the storage portion, the first fixing unit, and the second fixing unit.

Assignees

• Hitachi High Tech Corp

Inventors

• Noda Kazuki
• Ooura Takeshi
• KARIYA Shunichi

Classifications

• G01N27/44791

  Microapparatus (sample containers with integrated microfluidic structures B01L3/5027) · CPC title

• G01N27/44704 Primary

  Details; Accessories · CPC title

• G01N27/447 Primary

  using electrophoresis · CPC title