Cell penetrating peptide
US-11414456-B2 · Aug 16, 2022 · US
US2022356207A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2022356207-A1 |
| Application number | US-202217854647-A |
| Country | US |
| Kind code | A1 |
| Filing date | Jun 30, 2022 |
| Priority date | Dec 11, 2017 |
| Publication date | Nov 10, 2022 |
| Grant date | — |
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An object of the present invention is to provide a cell penetrating peptide having a penetrating ability into cells. The present inventors provided a cell penetrating peptide consisting of the amino acid sequence of SEQ ID NO: 1, a cell penetrating peptide consisting of the amino acid sequence of SEQ ID NO: 2 and a cell penetrating peptide consisting of the amino acid sequence of SEQ ID NO: 3; and a complex comprising any one of the cell penetrating peptide and a functional molecule.
Opening claim text (preview).
1 . A polynucleotide comprising a nucleotide sequence encoding a peptide consisting of the amino acid sequence of SEQ ID NO: 1. 2 . A polynucleotide comprising a nucleotide sequence encoding the complex comprising the peptide consisting of the amino acid sequence of SEQ ID NO: 1 and a functional molecule, wherein the functional molecule is polypeptides. 3 . A complex comprising the peptide consisting of the amino acid sequence of SEQ ID NO: 1 and a functional molecule, wherein the functional molecule is selected from the group consisting of low molecular compounds, polynucleotides, polypeptides, lipids, carbohydrates, other high molecular compounds, magnetic particles and physiologically active substances. 4 . The complex according to claim 3 , wherein the functional molecule is selected from the group consisting of polynucleotides, polypeptides, lipids, carbohydrates, magnetic particles and liposomes.
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having 5 to 11 amino acids · CPC title
containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP] · CPC title
Fusion polypeptide · CPC title
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