Devices, systems, and methods for treating volume overload
US-2024423627-A1 · Dec 26, 2024 · US
Macrophage imaging agent
US2022226512A1 · US · A1
| Field | Value |
|---|---|
| Publication number | US-2022226512-A1 |
| Application number | US-202017614753-A |
| Country | US |
| Kind code | A1 |
| Filing date | May 27, 2020 |
| Priority date | May 31, 2019 |
| Publication date | Jul 21, 2022 |
| Grant date | — |
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- Title
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Abstract
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Composite particles, each of which is obtained by forming, on the surface of a gadolinium oxide-containing particle, a cover film that contains a polymer obtained by polymerizing a monomer component containing a monomer having an ethylenically unsaturated bond; a macrophage imaging agent which contains the composite particles; and a method for producing composite particles, wherein a monomer component containing a monomer having an ethylenically unsaturated bond and gadolinium oxide-containing particles are mixed with each other, and after emulsifying the thus-obtained monomer component-containing mixture in water in the presence of a surfactant and a polymerization initiator in water, the monomer component is polymerized, thereby forming cover films on the surfaces of the gadolinium oxide-containing particles.
First claim
Opening claim text (preview).
1 . A macrophage imaging agent used for macrophage imaging by a magnetic resonance imaging method, comprising composite particles in which a coating film containing a polymer made by polymerizing a monomer component containing a monomer having an ethylenically unsaturated bond is formed on the surface of a gadolinium oxide-containing particle. 2 . A composite particle used in a macrophage imaging agent, comprising a gadolinium oxide-containing particle and a coating film containing a polymer made by polymerizing a monomer component containing a monomer having an ethylenically unsaturated bond, wherein the coating film is formed on the surface of the gadolinium oxide-containing particle. 3 . A method for producing the composite particle according to claim 2 , comprising: mixing a monomer component comprising a monomer having an ethylenically unsaturated bond with a gadolinium oxide-containing particle, emulsifying the resulting monomer component-containing mixture in water in the presence of a surfactant and a polymerization initiator, and thereafter polymerizing the monomer component to form a coating film on the surface of the gadolinium oxide-containing particle.
Assignees
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Classifications
- A61B5/055Primary
involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging · CPC title
- A61K49/08Primary
characterised by the carrier · CPC title
the organic macromolecular compound being obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly(meth)acrylate, polyacrylamide, polyvinylpyrrolidone, polyvinylalcohol · CPC title
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- What does patent US2022226512A1 cover?
- Composite particles, each of which is obtained by forming, on the surface of a gadolinium oxide-containing particle, a cover film that contains a polymer obtained by polymerizing a monomer component containing a monomer having an ethylenically unsaturated bond; a macrophage imaging agent which contains the composite particles; and a method for producing composite particles, wherein a monomer co…
- Who is the assignee on this patent?
- Univ Kyoto, Nat Cerebral & Cardiovascular Ct, Jsr Corp
- What technology area does this patent fall under?
- Primary CPC classification A61B5/055. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Thu Jul 21 2022 00:00:00 GMT+0000 (Coordinated Universal Time) (A1). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).