Dental restorative curable composition

Patent metadata

Field	Value
Publication number	US-2022218572-A1
Application number	US-202017605951-A
Country	US
Kind code	A1
Filing date	Apr 23, 2020
Priority date	Apr 24, 2019
Publication date	Jul 14, 2022
Grant date	—

Abstract

A dental restorative curable compositions may have a high mechanical strength and excellent water resistance and polishability in the form of a cured product. A dental composite resin may include such compositions. A dental mill blank may include the cured product of such compositions. A dental restorative curable composition may include: a (meth)acrylic acid ester compound (A) having two or more (meth)acryloyloxy groups per molecule; a mono(meth)acrylic acid ester compound (B); an inorganic filler (C) having an average primary particle diameter of 0.01 to 5 μm; and a polymerization initiator (D). The mono(meth)acrylic acid ester compound may include at least one selected from the group consisting of a mono(meth)acrylic acid ester compound (B-1) of formula (I):

and

a mono(meth)acrylic acid ester compound (B-2) of formula (II):

First claim

1 . A dental restorative curable composition, comprising:
a (meth)acrylic acid ester compound (A) comprising two or more (meth)acryloyloxy groups per molecule; a mono(meth)acrylic acid ester compound (B); an inorganic filler (C) having an average primary particle diameter in a range of from 0.01 to 5 μm; and a polymerization initiator (D), wherein the mono(meth)acrylic acid ester compound (B) comprises at least one selected from the group consisting of a mono(meth)acrylic acid ester compound (B-1) of formula (I)

and a mono(meth)acrylic acid ester compound (B-2) represented by the following general formula (II),

X being O or a divalent hydrocarbon group comprising 1 to 6 carbon atoms, and R 1 and R 2 each independently being a first group of formula (i)

or a second group of formula (ii)

R 3 and R 5 each independently being a divalent hydrocarbon group comprising 1 to 10 carbon atoms, R 4 and R 6 each independently being H or a methyl group, and k and l each independently being an integer in a range of from 0 to 6.

2 . The composition of claim 1 , wherein the inorganic filler (C) is present in a range of from 50 to 95 mass % with respect to a total dental restorative curable composition mass.

3 . The composition of claim 1 , wherein the mono(meth)acrylic acid ester compound (B) comprises the mono(meth)acrylic acid ester compound (B-2 of formula (II).

4 . The composition of claim 3 , wherein X is an oxygen atom.

5 . The composition of claim 1 , wherein k and l are each 0 or 1.

6 . The composition of claim 1 , wherein the (meth)acrylic acid ester compound (A) comprises a compound comprising a ring structure.

7 . The composition of claim 6 , wherein the compound having the ring structure is a compound (A-1) having an aromatic ring.

8 . The composition of claim 7 , wherein the compound (A-1) having an aromatic ring is a compound having a bisphenol A skeleton.

9 . The composition of claim 1 , wherein the (meth)acrylic acid ester compound (A) comprises a compound having none of a hydroxy group, a carboxy group, a primary amino group, a secondary amino group, an amide group, a urea bond, and a urethane bond.

10 . The composition of claim 1 , which is essentially free of a compound having a heterocyclic ring having a nitrogen atom and a polymerizable functional group.

11 . The composition of claim 1 , wherein the polymerization initiator (D) comprises a photopolymerization initiator.

12 . The composition of claim 1 , wherein the polymerization initiator (D) comprises a thermal polymerization initiator.

13 . The composition of claim 1 , further comprising:
a polymer.

14 . The composition of claim 13 , wherein the polymer is a prepolymer having art unreacted polymerizable functional group.

15 . The composition of claim 14 , wherein a number of unreacted polymerizable functional groups per molecule in the prepolymer is in a range of from 5 to 1,000.

16 . The composition of claim 14 , wherein a weight-average molecular weight of the prepolymer is in a range of from 1,000 to 1,000,000.

17 . A dental composite resin, comprising:
the dental restorative curable composition of claim 1 .

18 . A dental mill blank, comprising:
the dental restorative curable composition of claim 1 .

Assignees

• Kuraray Noritake Dental Inc

Inventors

• Inoue Masashi
• ICHIKAWA Seiya
• Suzuki Kenji
• Miyakawa Hayato
• Kajikawa Tatsuya
• Horiguchi Hirotaka

Classifications

• A61K6/71 Primary

  Fillers · CPC title

• A61K6/62

  Photochemical radical initiators · CPC title

• A61K6/64

  Thermal radical initiators · CPC title

• A61K6/889 Primary

  Polycarboxylate cements; Glass ionomer cements · CPC title