Apparatus for producing radionuclide and method for producing radionuclide

Patent metadata

Field	Value
Publication number	US-2022199277-A1
Application number	US-202017601467-A
Country	US
Kind code	A1
Filing date	Feb 12, 2020
Priority date	May 9, 2019
Publication date	Jun 23, 2022
Grant date	—

Abstract

An object of the invention is to efficiently produce a radionuclide. While a fluid containing a raw material is circulated along a circulation passage, a first radionuclide is generated in the fluid from the raw material by irradiating the fluid with radiation rays midway along the circulation passage. Further, while the fluid is circulated along the circulation passage, a substance containing at least a part of the first radionuclide and a second radionuclide generated from the first radionuclide is taken out from the fluid, and the fluid containing the remaining raw material is returned to the circulation passage again for circulation.

First claim

1 . An apparatus for producing a radionuclide, comprising:
a circulation passage along which a fluid containing a raw material is circulated; a radiation generator configured to emit radiation rays to at least a part of the circulation passage to generate a first radionuclide from the raw material; and a separation device configured to take out, from the fluid circulating in the circulation passage, a substance containing at least a part of the first radionuclide and a second radionuclide generated from the first radionuclide, and return the fluid containing the remaining raw material to the circulation passage.

2 . The apparatus for producing a radionuclide according to claim 1 , wherein
the radiation generator includes an electron beam accelerator configured to emit an accelerated electron beam and a holding unit configured to hold a target for braking radiation rays at a position to be irradiated with the electron beam emitted from the electron beam accelerator, and the radiation generator is configured to irradiate the fluid with braking radiation rays generated from the target for braking radiation rays irradiated with the electron beam.

3 . The apparatus for producing a radionuclide according to claim 1 , wherein
the fluid is any one of a solution in which the raw material is dissolved in a solvent, a dispersion solution in which the raw material is dispersed in a solvent, and dispersion gas in which the raw material is dispersed in gas.

4 . The apparatus for producing a radionuclide according to claim 1 , wherein
a part of the circulation passage has a linear region in a direction in which the fluid flows, the radiation generator is disposed such that a central axis of the radiation rays emitted by the radiation generator passes through the linear region of the circulation passage.

5 . The apparatus for producing a radionuclide according to claim 1 , wherein
the circulation passage is provided with a discharge port through which a gaseous nuclide generated by decay of the radionuclide contained in the fluid is discharged.

6 . The apparatus for producing a radionuclide according to claim 1 , wherein
the at least a part of the circulation passage is made of a material that generates braking radiation rays by being irradiated with an electron beam, the radiation generator is an electron beam accelerator configured to emit an accelerated electron beam, and is configured to emit the electron beam toward the circulation passage made of the material that generates the braking radiation rays so as to irradiate the fluid flowing in the circulation passage with the braking radiation rays.

7 . The apparatus for producing a radionuclide according to claim 1 , further comprising:
a pump provided in the circulation passage; and a control unit configured to control the pump, wherein the control unit is configured to adjust at least one of an operation time and a stop time of the pump, and a flow rate during a pump operation.

8 . The apparatus for producing a radionuclide according to claim 1 , wherein
the circulation passage is provided with a cooling unit configured to cool the fluid.

9 . The apparatus for producing a radionuclide according to claim 2 , wherein
the radiation generator includes a plurality of radiation generators, and the radiation generators are configured to respectively irradiate different portions of the circulation passage with braking radiation rays.

10 . The apparatus for producing a radionuclide according to claim 1 , wherein
the circulation passage is provided with a bypass passage configured to bypass the separation device.

11 . A method for producing a radionuclide, comprising:
irradiating, while a fluid containing a raw material is circulated along a circulation passage, the fluid with radiation rays midway along the circulation passage to generate a first radionuclide in the fluid from the raw material; and while the fluid is circulated along the circulation passage, taking out, from the fluid, a substance containing at least a part of the first radionuclide and a second radionuclide generated from the first radionuclide, and returning the fluid containing the remaining raw material to the circulation passage again for circulation.

12 . The method for producing a radionuclide according to claim 11 , wherein
the radiation rays are braking radiation rays generated by irradiating a target with accelerated electrons.

13 . The method for producing a radionuclide according to claim 11 , wherein
the raw material is radium-226 (Ra-226), the first radionuclide is radium-225 (Ra-225), and the second radionuclide is actinium-225 (Ac-225).

14 . The method for producing a radionuclide according to claim 11 , wherein
the raw material is molybdenum-100 (Mo-100) or molybdenum trioxide 100, the first radionuclide is molybdenum-99 (Mo-99), and the second radionuclide is technetium-99m (Te-99m).

15 . The method for producing a radionuclide according to claim 11 , wherein
the fluid is any one of a solution in which the raw material is dissolved in a solvent, a dispersion solution in which the raw material is dispersed in a solvent, and dispersion gas in which the raw material is dispersed in gas.

Assignees

• Hitachi Ltd

Inventors

• Tadokoro Takahiro
• Ueno Yuichiro
• KANI Yuuko

Classifications

• G21G2001/0089

  Actinium · CPC title

• G21G1/12 Primary

  by electromagnetic irradiation, e.g. with gamma or X-rays (applications of radiation G21H5/00; irradiation devices G21K5/00) · CPC title

• G21G2001/0036

  Molybdenum · CPC title

• G21K5/08

  Holders for targets or for other objects to be irradiated · CPC title