Automatic analysis device

Patent metadata

Field	Value
Publication number	US-2022170956-A1
Application number	US-202017600134-A
Country	US
Kind code	A1
Filing date	Mar 5, 2020
Priority date	Apr 26, 2019
Publication date	Jun 2, 2022
Grant date	—

Abstract

There is provided an automatic analysis device with a structure in which a measurement unit is less susceptible to disturbance as compared to a device in the related art, and a method of designing the automatic analysis device. A first rotation axis 301 of a reaction disk 1, a second rotation axis 302 of a reagent disk 9, and a measurement unit are arranged on the same straight line 311 when an automatic analysis device 100 is viewed from an upper surface side, the first rotation axis 301 of the reaction disk 1 is arranged between the second rotation axis 302 of the reagent disk 9 and the measurement unit, and the measurement unit is arranged on a front side to be accessed by a user of the automatic analysis device 100.

First claim

1 . An automatic analysis device comprising:
a reaction disk that includes a plurality of reaction containers circumferentially arranged thereon, the reaction container being configured to react a sample with the reagent; a reagent disk configured to keep a plurality of reagent containers containing the reagent; a stirring mechanism configured to stir a liquid held in the reaction container; a measurement unit configured to measure physical properties of the liquid held in the reaction container; and a cleaning mechanism configured to clean the reaction container after the measurement, wherein when a housing constituting the automatic analysis device is viewed from a top side, the reaction disk is disposed on a first corner side that is one of two corners located at both ends of a first side on a front surface side of the housing to be accessed by a user, the reagent disk is disposed on a rear surface side of the housing facing the first side, and on a second corner side located diagonally to the first corner among two corners located on both ends of a second side, the measurement unit is disposed on a straight line passing through a rotation axis of the reagent disk and a rotation axis of the reaction disk and on the first corner side than the rotation axis of the reaction disk around the reaction disk, and when an orthogonal line passing through the rotation axis of the reaction disk and orthogonal to the straight line is drawn, the stirring mechanism and the cleaning mechanism are disposed on the reagent disk side of the orthogonal line.

2 . The automatic analysis device according to claim 1 , wherein
the straight line is neither parallel nor vertical to any of sides of the housing.

3 . The automatic analysis device according to claim 1 , wherein
the measurement unit includes a slit that is configured to diffract light passing through the liquid in the reaction container, a diffraction grating that is configured to disperse light passing through the slit, and a multi-wavelength detector that is configured to detect the light dispersed by the diffraction grating, and at least the diffraction grating and the multi-wavelength detector are arranged on the straight line.

4 .- 6 . (canceled)

7 . The automatic analysis device according to claim 1 , further comprising:
a reagent dispensing mechanism that is configured to dispense the reagent into the reaction containers, wherein the reagent dispensing mechanism is arranged at a position adjacent to outer peripheries of the reaction disk and the reagent disk.

8 . The automatic analysis device according to claim 7 , further comprising:
a sample dispensing mechanism that is configured to dispense the sample into the reaction containers, wherein in the reaction containers of the reaction disk stopped during dispensing of the sample by the sample dispensing mechanism or during dispensing of the reagent by the reagent dispensing mechanism, a reaction container arranged at a position closest to the measurement position of the measurement unit is a reaction container during or after cleaning by the cleaning mechanism.

9 . The automatic analysis device according to claim 7 , wherein
the reagent disk has a reagent suction position to be accessed by the reagent dispensing mechanism when the reagent is dispensed into the reaction container, and the reagent suction position is arranged on the straight line.

10 . The automatic analysis device according to claim 7 , further comprising:
a sample dispensing mechanism that is configured to dispense the sample into the reaction containers, wherein the reaction disk is configured to rotationally move and stop the reaction containers at least once within one cycle, and a sample discharging position of the sample dispensing mechanism is set while the reaction disk is rotationally moved from the measurement unit to a reagent disk side.

11 . The automatic analysis device according to claim 7 , wherein the reaction disk rotates and stops the reaction container at least once within one cycle, and
a stirring position of the stirring mechanism is provided while the reaction disk is rotationally moved from the reagent disk to a measurement unit side.

12 . The automatic analysis device according to claim 1 , wherein
when a total number of the reaction containers is set to N, the number of the reaction containers by which the reaction disk moves in one cycle is set to A (N+1≥A), and after B (B≥1) cycles, the reaction disk is set to rotationally move by C (C≥1) rotations±a movement amount equivalent to one reaction container, the N and the A are mutually prime, the B and the C are mutually prime, the B is an odd number, and the reaction disk is rotationally controlled such that the reaction container moves by an amount A in the circumferential direction in one cycle so as to satisfy a relationship of A×B=N×C±1.

13 . The automatic analysis device according to claim 1 , wherein
the reaction disk and the measurement unit are fixed to the same first base.

14 . The automatic analysis device according to claim 13 , further comprising:
a sample dispensing mechanism that is configured to dispense the sample into the reaction containers and a reagent dispensing mechanism that is configured to dispense the reagent into the reaction containers, wherein the sample dispensing mechanism, the reagent dispensing mechanism, and the stirring mechanism are fixed to a second base that is different from the first base.

15 . The automatic analysis device according to claim 14 , wherein
the reagent disk is fixed to a third base that is different from the first base and the second base, and the first base and the third base are connected to each other across the second base.

16 . (canceled)

17 . The automatic analysis device according to claim 1 , wherein
a position at which the physical properties of the liquid held in the reaction container are measured by the measurement unit is a position at which the reaction container is stopped during or after cleaning in which the measurement is finished and cleaning by the cleaning mechanism is started.

18 . The automatic analysis device according to claim 1 , further comprising:
a reagent dispensing mechanism that is configured to dispense the reagent into the reaction containers and has a plurality of rotation axes.

Assignees

• Hitachi High Tech Corp

Inventors

• Yasui Akihiro
• Setomaru Takeshi
• KIYOKAWA Akinori
• Fukaya Masashi

Classifications

• G01N2035/0446

  Combinations of the above · CPC title

• G01N2035/0444

  for cuvettes or reaction vessels · CPC title

• G01N2035/0094

  optimisation; experiment design · CPC title

• G01N35/04

  Details of the conveyor system {(G01N35/021 - G01N35/028 take precedence)} · CPC title

• G01N35/0092

  Scheduling · CPC title